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| | AII44795.1 | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (328 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (216 aa) |
| | trpA | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (271 aa) |
| | hisI | phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; In the N-terminal section; belongs to the PRA-CH family. (222 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (435 aa) |
| | AII44960.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (127 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (315 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (310 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (370 aa) |
| | ilvA | L-threonine dehydratase biosynthetic IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (509 aa) |
| | hisZ | Hypothetical protein; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (392 aa) |
| | mtnP | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (298 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (368 aa) |
| | dapF | Hypothetical protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (365 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (322 aa) |
| | AII45261.1 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1194 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the IlvD/Edd family. (557 aa) |
| | AII45416.1 | Glutamine synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (473 aa) |
| | carA | Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (390 aa) |
| | trpD | Hypothetical protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (338 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (441 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (459 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (330 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (325 aa) |
| | AII45633.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (318 aa) |
| | AII45644.1 | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (441 aa) |
| | metAA | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (297 aa) |
| | carB | Carbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1104 aa) |
| | AII45673.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (266 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (277 aa) |
| | AII45677.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (216 aa) |
| | accD | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (293 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (357 aa) |
| | proB | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (359 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (255 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (293 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (540 aa) |
| | hisH | Hypothetical protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa) |
| | AII45812.1 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (438 aa) |
| | AII45846.1 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (176 aa) |
| | proC | Hypothetical protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (266 aa) |
| | mtnD | Hypothetical protein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (186 aa) |
| | bioD | Hypothetical protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (219 aa) |
| | AII45903.1 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (430 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (437 aa) |
| | fabZ | 3-hydroxyacyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (151 aa) |
| | AII46020.1 | 3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa) |
| | AII46114.1 | Acyl carrier protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (93 aa) |
| | AII46115.1 | 3-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (422 aa) |
| | AII46156.1 | acetyl-CoA carboxylase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (191 aa) |
| | AII46261.1 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (265 aa) |
| | AII44803.1 | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (322 aa) |
| | plsX | Glycerol-3-phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (436 aa) |
| | fabH | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (339 aa) |
| | AII46294.1 | Malonyl CoA-ACP transacylase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (298 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (418 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (409 aa) |
| | AII46430.1 | Chorismate lyase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (178 aa) |
| | AII46479.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (269 aa) |
| | AII46528.1 | Anthranilate phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (356 aa) |
| | AII46536.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (355 aa) |
| | aroE | Hypothetical protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (289 aa) |
| | argG | Argininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (403 aa) |
| | AII46562.1 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (368 aa) |
| | argH | Argininosuccinate lyase; Catalyzes the formation of arginine from (N-L-arginino)succinate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (472 aa) |
| | AII46593.1 | Carboxylesterase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (156 aa) |
| | AII46607.1 | Class V aminotransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (388 aa) |
| | AII46629.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (227 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (302 aa) |
| | AII46633.1 | Aspartate kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (601 aa) |
| | AII46662.1 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (248 aa) |
| | AII46696.1 | Hydrolase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (389 aa) |
| | AII46703.1 | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (415 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (80 aa) |
| | AII46732.1 | Hypothetical protein; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (256 aa) |
| | kdsA | 2-dehydro-3-deoxyphosphooctonate aldolase; Catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the KdsA family. (283 aa) |
| | AII46761.1 | UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (467 aa) |
| | AII46776.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (159 aa) |
| | AII46784.1 | enoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (260 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (202 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (429 aa) |
| | leuC | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa) |
| | AII46819.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the LeuD family. (203 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (362 aa) |
| | dapL | Aspartate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (408 aa) |
| | pheA | Chorismate mutase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (288 aa) |
| | AII46886.1 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1534 aa) |
| | lipA-2 | Radical SAM protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (289 aa) |
| | AII46915.1 | Hypothetical protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (375 aa) |
| | AII46937.1 | Arogenate dehydrogenase; Catalyzes the formation of tyrosine from arogenate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (288 aa) |
| | AII46943.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (291 aa) |
| | panC/cmk | Hypothetical protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. (478 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (147 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (425 aa) |
| | AII47111.1 | Hypothetical protein; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (127 aa) |
| | AII47146.1 | 3-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (250 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (293 aa) |
| | AII47251.1 | Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (618 aa) |
| | AII47260.1 | Fatty aldehyde?generating acyl-ACP reductase; in cyanobacteria this enzyme functions in alkane biosynthesis along with aldehyde decarbonylase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (346 aa) |
| | accA | acetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (329 aa) |
| | trpF | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TrpF family. (223 aa) |
| | AII47301.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (425 aa) |
| | AII47302.1 | Asparagine synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (674 aa) |
| | hisF | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (256 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (271 aa) |
| | argD | Acetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (393 aa) |
| | trpC | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TrpC family. (251 aa) |
