STRINGSTRING
secA secA aceF aceF ycaD_2 ycaD_2 frmA frmA APC12577.1 APC12577.1 ndk ndk bcr_3 bcr_3 bcr_2 bcr_2 proP_4 proP_4 bcp bcp ftnA ftnA secE secE tufA_1 tufA_1 dppC_1 dppC_1 dppB dppB dppA_1 dppA_1 rpoZ rpoZ pstS pstS sspH1 sspH1 proP_2 proP_2 emrB_2 emrB_2 APC09900.1 APC09900.1 emrB_1 emrB_1 sodA sodA asnC asnC smvA smvA APC09739.1 APC09739.1 mdtL_1 mdtL_1 sotB sotB oppC oppC shlA_2 shlA_2 shlA_1 shlA_1 sodB sodB dppA_2 dppA_2 APC10556.1 APC10556.1 APC10549.1 APC10549.1 APC10542.1 APC10542.1 APC10539.1 APC10539.1 APC10538.1 APC10538.1 hpmA hpmA fhaB_1 fhaB_1 mdlB mdlB mlaD mlaD tetA_2 tetA_2 oppD_4 oppD_4 gsiC_3 gsiC_3 hbpA hbpA secG secG msrA msrA yheI yheI lrp_1 lrp_1 APC10459.1 APC10459.1 yajR yajR ribD ribD secF secF secD secD tsaA_1 tsaA_1 ycaD_1 ycaD_1 APC10261.1 APC10261.1 APC10184.1 APC10184.1 rpoC rpoC rpoB rpoB sodC1 sodC1 ynfM_2 ynfM_2 APC11900.1 APC11900.1 APC11899.1 APC11899.1 ymfD ymfD ydhP ydhP APC11885.1 APC11885.1 ybjJ ybjJ APC11880.1 APC11880.1 ahpC ahpC mdtH mdtH lrp_3 lrp_3 APC10561.1 APC10561.1 APC10565.1 APC10565.1 APC10570.1 APC10570.1 inlA inlA trxA_1 trxA_1 appA_1 appA_1 gsiC_1 gsiC_1 dppC_2 dppC_2 wzb_1 wzb_1 lplT lplT emrB_3 emrB_3 ynfM_1 ynfM_1 imm imm ydhC_1 ydhC_1 sucB sucB trxB trxB lrp_2 lrp_2 rhmT_1 rhmT_1 APC10987.1 APC10987.1 msbA msbA tetA_1 tetA_1 APC11431.1 APC11431.1 ahpD_2 ahpD_2 stp_1 stp_1 csbX_2 csbX_2 limB limB APC10559.1 APC10559.1 ydhC_2 ydhC_2 oppB oppB wzb_2 wzb_2 viuB viuB emrD emrD tufA_2 tufA_2 bfr bfr secY secY rpoA rpoA trxA_3 trxA_3 appA_2 appA_2 gsiC_2 gsiC_2 dppC_3 dppC_3 hsrA_2 hsrA_2 tpx tpx shlA_3 shlA_3 fhaB_2 fhaB_2 fsr fsr trxA_2 trxA_2 APC12947.1 APC12947.1 aac aac APC12814.1 APC12814.1 iolT iolT
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (903 aa)
aceFDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (622 aa)
ycaD_2Putative MFS-type transporter YcaD. (387 aa)
frmAS-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (370 aa)
APC12577.1S-(hydroxymethyl)mycothiol dehydrogenase. (364 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa)
bcr_3Bicyclomycin resistance protein. (156 aa)
bcr_2Bicyclomycin resistance protein. (237 aa)
proP_4Proline/betaine transporter. (451 aa)
bcpPutative peroxiredoxin bcp. (156 aa)
ftnAFerritin-1; Iron-storage protein. (167 aa)
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (128 aa)
tufA_1Elongation factor Tu. (394 aa)
dppC_1Dipeptide transport system permease protein DppC. (300 aa)
dppBDipeptide transport system permease protein DppB. (339 aa)
dppA_1Periplasmic dipeptide transport protein precursor. (535 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (91 aa)
pstSPhosphate-binding protein PstS precursor; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (347 aa)
sspH1E3 ubiquitin-protein ligase sspH1. (318 aa)
proP_2Proline/betaine transporter. (500 aa)
emrB_2Multidrug export protein EmrB; Belongs to the major facilitator superfamily. (507 aa)
APC09900.1Hypothetical protein. (194 aa)
emrB_1Multidrug export protein EmrB. (504 aa)
sodASuperoxide dismutase [Mn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (208 aa)
asnCRegulatory protein AsnC. (153 aa)
smvAMethyl viologen resistance protein SmvA. (495 aa)
APC09739.1Putative multidrug-efflux transporter. (469 aa)
mdtL_1Multidrug resistance protein MdtL. (394 aa)
sotBSugar efflux transporter; Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites; Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family. (401 aa)
oppCOligopeptide transport system permease protein OppC. (302 aa)
shlA_2Hemolysin precursor. (719 aa)
shlA_1Hemolysin precursor. (716 aa)
sodBSuperoxide dismutase [Fe]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (192 aa)
dppA_2Periplasmic dipeptide transport protein precursor. (561 aa)
APC10556.1Hypothetical protein. (150 aa)
APC10549.1Hypothetical protein. (531 aa)
APC10542.1Hypothetical protein. (291 aa)
APC10539.1Hypothetical protein. (81 aa)
APC10538.1Hypothetical protein. (512 aa)
hpmAHemolysin precursor. (3919 aa)
fhaB_1Filamentous hemagglutinin. (1764 aa)
mdlBMultidrug resistance-like ATP-binding protein MdlB. (594 aa)
mlaDPutative phospholipid ABC transporter-binding protein MlaD. (165 aa)
tetA_2Tetracycline resistance protein, class B. (400 aa)
oppD_4Oligopeptide transport ATP-binding protein OppD; Belongs to the binding-protein-dependent transport system permease family. (597 aa)
gsiC_3Glutathione transport system permease protein GsiC. (315 aa)
hbpAHeme-binding protein A precursor. (519 aa)
secGProtein-export membrane protein SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (114 aa)
msrAPeptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (213 aa)
yheIPutative multidrug resistance ABC transporter ATP-binding/permease protein YheI. (581 aa)
lrp_1Leucine-responsive regulatory protein. (153 aa)
APC10459.1Muropeptide transporter. (500 aa)
yajRInner membrane transport protein YajR. (425 aa)
ribDRiboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (371 aa)
secFPreprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (322 aa)
secDPreprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (604 aa)
tsaA_1Putative peroxiredoxin. (200 aa)
ycaD_1Putative MFS-type transporter YcaD. (398 aa)
APC10261.1Multidrug efflux system protein MdtL. (349 aa)
APC10184.1Hypothetical protein. (327 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1406 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1342 aa)
sodC1Superoxide dismutase [Cu-Zn] 1 precursor; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (174 aa)
ynfM_2Inner membrane transport protein YnfM. (422 aa)
APC11900.1Putative transporter. (155 aa)
APC11899.1Putative transporter. (240 aa)
ymfDBacillibactin exporter. (388 aa)
ydhPInner membrane transport protein YdhP. (392 aa)
APC11885.1Acetyltransferase (GNAT) family protein. (260 aa)
ybjJInner membrane protein YbjJ. (386 aa)
APC11880.1Acetyltransferase (GNAT) family protein. (257 aa)
ahpCAlkyl hydroperoxide reductase subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
mdtHMultidrug resistance protein MdtH. (401 aa)
lrp_3Leucine-responsive regulatory protein. (153 aa)
APC10561.1Hypothetical protein. (294 aa)
APC10565.1Hypothetical protein. (554 aa)
APC10570.1Hypothetical protein. (77 aa)
inlAInternalin-A precursor. (291 aa)
trxA_1Thioredoxin. (114 aa)
appA_1Oligopeptide-binding protein AppA precursor. (529 aa)
gsiC_1Glutathione transport system permease protein GsiC. (322 aa)
dppC_2Dipeptide transport system permease protein DppC. (268 aa)
wzb_1Low molecular weight protein-tyrosine-phosphatase wzb. (142 aa)
lplTLysophospholipid transporter LplT. (400 aa)
emrB_3Multidrug export protein EmrB; Belongs to the major facilitator superfamily. (511 aa)
ynfM_1Inner membrane transport protein YnfM. (399 aa)
immColicin-E3 immunity protein. (85 aa)
ydhC_1Inner membrane transport protein YdhC. (377 aa)
sucBDihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (403 aa)
trxBThioredoxin reductase. (319 aa)
lrp_2Leucine-responsive regulatory protein. (164 aa)
rhmT_1Inner membrane transport protein RhmT. (437 aa)
APC10987.1Putative multidrug-efflux transporter. (471 aa)
msbALipid A export ATP-binding/permease protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (581 aa)
tetA_1Tetracycline resistance protein, class B. (408 aa)
APC11431.1Transposase DDE domain protein. (259 aa)
ahpD_2Alkyl hydroperoxide reductase AhpD; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (143 aa)
stp_1Multidrug resistance protein stp. (470 aa)
csbX_2Alpha-ketoglutarate permease. (429 aa)
limBLimonene 1,2-monooxygenase. (334 aa)
APC10559.1Hypothetical protein. (212 aa)
ydhC_2Inner membrane transport protein YdhC. (407 aa)
oppBOligopeptide transport system permease protein OppB. (306 aa)
wzb_2Low molecular weight protein-tyrosine-phosphatase wzb. (142 aa)
viuBVibriobactin utilization protein ViuB. (279 aa)
emrDMultidrug resistance protein D. (394 aa)
tufA_2Elongation factor Tu. (394 aa)
bfrBacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (157 aa)
secYPreprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (441 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (329 aa)
trxA_3Thioredoxin-1; Belongs to the thioredoxin family. (108 aa)
appA_2Oligopeptide-binding protein AppA precursor. (525 aa)
gsiC_2Glutathione transport system permease protein GsiC. (322 aa)
dppC_3Dipeptide transport system permease protein DppC. (270 aa)
hsrA_2Putative transport protein HsrA. (443 aa)
tpxThiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (167 aa)
shlA_3Hemolysin precursor. (1394 aa)
fhaB_2Filamentous hemagglutinin. (312 aa)
fsrFosmidomycin resistance protein. (407 aa)
trxA_2Thioredoxin. (285 aa)
APC12947.1Phage tail protein. (161 aa)
aacAminoglycoside 2'-N-acetyltransferase. (178 aa)
APC12814.1TPR repeat-containing protein precursor. (484 aa)
iolTMajor myo-inositol transporter IolT; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (468 aa)
Your Current Organism:
Providencia rettgeri
NCBI taxonomy Id: 587
Other names: ATCC 29944, Bacterium rettgeri, CCUG 14804, CIP 103182, DSM 4542, LMG 3259, LMG:3259, NCTC 11801, P. rettgeri, Proteus rettgeri, Shigella rettgeri
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