(34 nodes) Carbon metabolism, and Thiamin diphosphate-binding fold network (Theileria annulata)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Predicted Interactions

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protein homology

Your Input:
	TA11105	Glutamate dehydrogenase, putative. (1170 aa)
	TA10340	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (454 aa)
	TA10425	Enolase, putative. (442 aa)
	TA10465	Phosphoglycerate mutase, putative. (273 aa)
	TA10540	Triosephosphate isomerase. (371 aa)
	TA10625	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (329 aa)
	TA10850	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (459 aa)
	TA08590	Triosephosphate isomerase. (329 aa)
	TA08530	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (422 aa)
	TA08145	Glyceraldehyde-3-phosphate dehydrogenase. (339 aa)
	TA17295	50s ribosomal protein l16, putative. (175 aa)
	TA18725	Ribose 5-phosphate epimerase, putative. (240 aa)
	TA05220	Glucose-6-phosphate-1-dehydrogenase, putative. (878 aa)
	TA04045	Glucose-6-phosphate isomerase; Belongs to the GPI family. (560 aa)
	TA03455	Succinate dehydrogenase (Flavoprotein) subunit, putative. (592 aa)
	TA03445	Dihydrolipoyl dehydrogenase. (451 aa)
	TA05275	2-oxoglutarate dehydrogenase E1 component, putative. (1021 aa)
	TA04645	Thioredoxin reductase, putative; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (604 aa)
	TA12970	Aspartate aminotransferase, cytoplasmic, putative. (412 aa)
	TA13950	Probable ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily. (1725 aa)
	TA14450	Citrate synthase; Belongs to the citrate synthase family. (673 aa)
	TA15530	Glyceraldehyde 3-phosphate dehydrogenase, putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
	TA20060	Fructose-bisphosphate aldolase 2, putative. (377 aa)
	TA19350	6-phosphogluconate dehydrogenase, putative. (443 aa)
	TA19430	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (277 aa)
	TA19690	2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase). (457 aa)
	TA20880	Asparagine synthetase domain-containing protein. (618 aa)
	TA20470	1-deoxy-D-xylulose 5-phosphate synthase, putative. (761 aa)
	TA02815	Succinyl-coA ligase, subunit, putative. (433 aa)
	TA06600	Transketolase subunit, putative. (373 aa)
	TA06655	Phosphoglycerate kinase. (417 aa)
	TA16730	Phosphoribosyl pyrophosphate synthetase, putative. (325 aa)
	TA17020	Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (929 aa)
	TA09590	L-lactate dehydrogenase, putative; Belongs to the LDH/MDH superfamily. (367 aa)

Your Current Organism:

Theileria annulata

NCBI taxonomy Id: 5874
Other names: T. annulata

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TA02815	TA03445	Q4UHL1	Q4UCK8	Succinyl-coA ligase, subunit, putative.	Dihydrolipoyl dehydrogenase.	0.954
TA02815	TA03455	Q4UHL1	Q4UCK6	Succinyl-coA ligase, subunit, putative.	Succinate dehydrogenase (Flavoprotein) subunit, putative.	0.997
TA02815	TA04045	Q4UHL1	Q4UC94	Succinyl-coA ligase, subunit, putative.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.713
TA02815	TA04645	Q4UHL1	Q4UCW3	Succinyl-coA ligase, subunit, putative.	Thioredoxin reductase, putative; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.874
TA02815	TA05220	Q4UHL1	Q4UBM4	Succinyl-coA ligase, subunit, putative.	Glucose-6-phosphate-1-dehydrogenase, putative.	0.679
TA02815	TA05275	Q4UHL1	Q4UCU9	Succinyl-coA ligase, subunit, putative.	2-oxoglutarate dehydrogenase E1 component, putative.	0.991
TA02815	TA06600	Q4UHL1	Q4UIE9	Succinyl-coA ligase, subunit, putative.	Transketolase subunit, putative.	0.837
TA02815	TA06655	Q4UHL1	Q4UIF9	Succinyl-coA ligase, subunit, putative.	Phosphoglycerate kinase.	0.719
TA02815	TA08145	Q4UHL1	Q4U9T0	Succinyl-coA ligase, subunit, putative.	Glyceraldehyde-3-phosphate dehydrogenase.	0.544
TA02815	TA08530	Q4UHL1	Q4U9K9	Succinyl-coA ligase, subunit, putative.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.948
TA02815	TA08590	Q4UHL1	Q4U9J9	Succinyl-coA ligase, subunit, putative.	Triosephosphate isomerase.	0.543
TA02815	TA09590	Q4UHL1	Q4UJ29	Succinyl-coA ligase, subunit, putative.	L-lactate dehydrogenase, putative; Belongs to the LDH/MDH superfamily.	0.958
TA02815	TA10340	Q4UHL1	Q4U8X2	Succinyl-coA ligase, subunit, putative.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.789
TA02815	TA10425	Q4UHL1	Q4U8Y7	Succinyl-coA ligase, subunit, putative.	Enolase, putative.	0.753
TA02815	TA10465	Q4UHL1	Q4U8Z5	Succinyl-coA ligase, subunit, putative.	Phosphoglycerate mutase, putative.	0.742
TA02815	TA10540	Q4UHL1	Q4U908	Succinyl-coA ligase, subunit, putative.	Triosephosphate isomerase.	0.543
TA02815	TA10625	Q4UHL1	Q4U924	Succinyl-coA ligase, subunit, putative.	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.999
TA02815	TA10850	Q4UHL1	Q4U966	Succinyl-coA ligase, subunit, putative.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.925
TA02815	TA11105	Q4UHL1	Q4U8H1	Succinyl-coA ligase, subunit, putative.	Glutamate dehydrogenase, putative.	0.726
TA02815	TA12970	Q4UHL1	Q4UDB3	Succinyl-coA ligase, subunit, putative.	Aspartate aminotransferase, cytoplasmic, putative.	0.495