STRINGSTRING
TA09840 TA09840 TA10525 TA10525 TA10790 TA10790 TA10845 TA10845 TA08835 TA08835 TA08800 TA08800 TA08755 TA08755 TA08510 TA08510 TA08130 TA08130 TA08125 TA08125 TA07425 TA07425 TA07350 TA07350 TA07075 TA07075 TA09295 TA09295 TA17345 TA17345 TA17195 TA17195 TA18370 TA18370 TA17755 TA17755 TA18630 TA18630 TA18575 TA18575 TA18570 TA18570 TA05175 TA05175 TA04865 TA04865 TA04740 TA04740 TA04590 TA04590 TA04525 TA04525 TA04485 TA04485 TA04325 TA04325 TA04250 TA04250 MCM7 MCM7 TA03330 TA03330 TA03325 TA03325 TA02630 TA02630 TA02660 TA02660 TA11650 TA11650 TA13190 TA13190 TA14175 TA14175 TA15495 TA15495 TA16080 TA16080 TA11630 TA11630 TA12280 TA12280 TA12895 TA12895 TA12985 TA12985 TA13200 TA13200 TA13340 TA13340 TA13565 TA13565 TA13680 TA13680 TA14075 TA14075 TA14555 TA14555 TA15125 TA15125 TA15420 TA15420 TA15780 TA15780 FEN1 FEN1 TA15860 TA15860 TA15035 TA15035 TA19765 TA19765 TA19305 TA19305 TA20735 TA20735 TA20730 TA20730 TA20515 TA20515 TA02880 TA02880 TA06695 TA06695 TA06710 TA06710 TA06860 TA06860 TA05745 TA05745 TA05995 TA05995 TA06200 TA06200 TA06290 TA06290 TA16350 TA16350 TA16745 TA16745 TA17080 TA17080
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TA09840DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2210 aa)
TA10525Protein kinase, putative. (511 aa)
TA10790Replication factor C, putative. (840 aa)
TA10845Double-strand break repair protein, putative. (870 aa)
TA08835Uncharacterized protein. (305 aa)
TA08800DNA replication protein (MCM homologue), putative; Belongs to the MCM family. (945 aa)
TA08755ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (925 aa)
TA08510RECA_2 domain-containing protein. (73 aa)
TA08130Replication factor C subunit, putative. (347 aa)
TA08125CBFD_NFYB_HMF domain-containing protein. (182 aa)
TA07425Zf-primase domain-containing protein. (438 aa)
TA07350DNA repair (Rad51 homologue) protein, putative; Belongs to the RecA family. (369 aa)
TA07075Meiotic recombination (DMC1-like) protein, putative; Belongs to the RecA family. (409 aa)
TA09295Exonuclease 1, putative. (868 aa)
TA17345DNA helicase; Belongs to the MCM family. (916 aa)
TA17195Uncharacterized protein. (300 aa)
TA18370Sld5 domain-containing protein. (459 aa)
TA17755DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (607 aa)
TA18630Replication factor C subunit 1. (961 aa)
TA18575Uncharacterized protein. (129 aa)
TA18570Hypothtical protein. (227 aa)
TA05175DNA ligase. (899 aa)
TA04865DNA mismatch repair protein, putative. (847 aa)
TA04740Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (681 aa)
TA04590Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (274 aa)
TA04525Replication factor, putative. (299 aa)
TA04485DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (510 aa)
TA04325DNA repair (RAD6) endonuclease, putative. (1422 aa)
TA04250ERCC4 domain-containing protein. (894 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (827 aa)
TA03330DNA polymerase. (1074 aa)
TA03325Uncharacterized protein. (145 aa)
TA02630Mcl1_mid domain-containing protein. (1012 aa)
TA02660Endonuclease, putative. (586 aa)
TA11650Uncharacterized protein. (308 aa)
TA13190Nuclear transport factor 2, putative. (154 aa)
TA14175Uncharacterized protein. (1166 aa)
TA15495Replication protein A subunit. (625 aa)
TA16080Replication licensing factor, putative; Belongs to the MCM family. (1021 aa)
TA11630DNA repair protein rad50, putative. (1139 aa)
TA12280DNA_pol_E_B domain-containing protein. (627 aa)
TA12895Uncharacterized protein. (926 aa)
TA12985Uncharacterized protein. (418 aa)
TA13200Replication factor A-related protein, putative. (466 aa)
TA13340DNA polymerase delta small subunit, putative. (437 aa)
TA13565ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (875 aa)
TA13680DNA helicase. (903 aa)
TA14075Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
TA14555CDC6-like ATPase, putative. (458 aa)
TA15125PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (2446 aa)
TA15420DNA primase; Belongs to the eukaryotic-type primase small subunit family. (397 aa)
TA15780Uncharacterized protein. (286 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (506 aa)
TA15860UmuC domain-containing protein. (667 aa)
TA15035Uncharacterized protein. (2184 aa)
TA19765Origin recognition complex-like protein, putative. (509 aa)
TA19305DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1279 aa)
TA20735DNA mismatch repair protein msh2, putative. (651 aa)
TA20730MutS domain II, putative. (129 aa)
TA20515DNA replication licensing factor Mcm2, putative; Belongs to the MCM family. (1019 aa)
TA02880Minichromosome maintenance (MCM), putative; Belongs to the MCM family. (983 aa)
TA06695DNA replication licensing factor (MCM5 homologue), putative; Belongs to the MCM family. (770 aa)
TA06710MutS_I domain-containing protein. (887 aa)
TA06860DNA mismatch repair (MLH1 homologue), putative. (904 aa)
TA05745Recombinational repair (RAD54 homologue) protein. (806 aa)
TA05995DNA repair protein (RAD2 nuclease homologue), putative. (312 aa)
TA06200Uncharacterized protein. (968 aa)
TA06290DNA polymerase. (1088 aa)
TA16350Replication factor C subunit (RPC2 homologue), putative. (336 aa)
TA16745DNA repair protein (RAD10 homologue), putative. (216 aa)
TA17080Replication factor C subunit, putative. (351 aa)
Your Current Organism:
Theileria annulata
NCBI taxonomy Id: 5874
Other names: T. annulata
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