(32 nodes) Endoplasmic reticulum membrane network (Theileria annulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TA11365	ER lumen protein-retaining receptor. (223 aa)
	TA10110	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (239 aa)
	TA10130	Glycosyl transferase, putative. (468 aa)
	TA10570	Uncharacterized protein. (354 aa)
	TA10705	Uncharacterized protein. (562 aa)
	TA08609	Signal peptidase, putative. (173 aa)
	TA17425	Pre-protein translocase (SEC61 homologue), putative. (464 aa)
	TA17465	GPI anchor transamidase, putative. (405 aa)
	TA18300	Signal peptidase I. (183 aa)
	TA18065	Uncharacterized protein. (144 aa)
	TA18045	U5 small nuclear ribonucleoprotein-specific helicase, putative. (2248 aa)
	TA17685	Aspartyl(Acid) protease, putative; Belongs to the peptidase A1 family. (457 aa)
	TA04855	Cell divison cycle CDC48 homologue, putative or transitional endoplasmic reticulum ATPase, putative. (905 aa)
	TA04580	Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling. (203 aa)
	TA04335	Uncharacterized protein. (769 aa)
	TA04175	Protein translocation complex subunit (SEC61 gamma chain), putative. (82 aa)
	TA11460	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (209 aa)
	TA13100	Signal recognition particle receptor alpha subunit, putative. (547 aa)
	TA13145	ThiF domain-containing protein. (345 aa)
	TA13480	DNAJ-like sec63 homologue, putative. (656 aa)
	TA13655	Calcium-transporting ATPase, putative; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1305 aa)
	TA13670	Ubiquitin fusion degradation protein (UFD1 homologue), putative. (270 aa)
	TA14655	G_PROTEIN_RECEP_F1_2 domain-containing protein. (511 aa)
	TA15910	Uncharacterized protein. (1337 aa)
	TA18965	Udp-N-acetylglucosamine--dolichyl-phosphate n-acetylglucosaminephosphotransferase, putative. (392 aa)
	TA19480	Glycerol-3-phosphate acyltransferase, putative. (467 aa)
	TA02935	RING-type domain-containing protein. (625 aa)
	TA06685	Cation ATPase, putative; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1358 aa)
	TA06010	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (495 aa)
	TA06240	Protein-transport (SEC61 homologue), beta subunit, putative. (74 aa)
	TA06500	Transitional endoplasmic reticulum ATPase (CDC48 homologue), putative. (822 aa)
	TA16520	Ubiquitin-fusion degradation pathway component, UFD1 homologue, putative. (321 aa)

Your Current Organism:

Theileria annulata

NCBI taxonomy Id: 5874
Other names: T. annulata

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TA02935	TA04855	Q4UHI7	Q4UBT9	RING-type domain-containing protein.	Cell divison cycle CDC48 homologue, putative or transitional endoplasmic reticulum ATPase, putative.	0.869
TA02935	TA06500	Q4UHI7	Q4UID0	RING-type domain-containing protein.	Transitional endoplasmic reticulum ATPase (CDC48 homologue), putative.	0.869
TA02935	TA10110	Q4UHI7	Q4U8T0	RING-type domain-containing protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.891
TA02935	TA11460	Q4UHI7	Q4UDI1	RING-type domain-containing protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.891
TA02935	TA13480	Q4UHI7	Q4UEJ6	RING-type domain-containing protein.	DNAJ-like sec63 homologue, putative.	0.437
TA02935	TA13670	Q4UHI7	Q4UEN1	RING-type domain-containing protein.	Ubiquitin fusion degradation protein (UFD1 homologue), putative.	0.629
TA02935	TA15910	Q4UHI7	Q4UFR3	RING-type domain-containing protein.	Uncharacterized protein.	0.891
TA02935	TA16520	Q4UHI7	Q4UIX9	RING-type domain-containing protein.	Ubiquitin-fusion degradation pathway component, UFD1 homologue, putative.	0.629
TA02935	TA17425	Q4UHI7	Q4UAV1	RING-type domain-containing protein.	Pre-protein translocase (SEC61 homologue), putative.	0.735
TA04175	TA04580	Q4UC71	Q4UBZ7	Protein translocation complex subunit (SEC61 gamma chain), putative.	Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling.	0.732
TA04175	TA06010	Q4UC71	Q4UI41	Protein translocation complex subunit (SEC61 gamma chain), putative.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.563
TA04175	TA06240	Q4UC71	Q4UI84	Protein translocation complex subunit (SEC61 gamma chain), putative.	Protein-transport (SEC61 homologue), beta subunit, putative.	0.999
TA04175	TA08609	Q4UC71	Q4UAJ0	Protein translocation complex subunit (SEC61 gamma chain), putative.	Signal peptidase, putative.	0.518
TA04175	TA10570	Q4UC71	Q4U914	Protein translocation complex subunit (SEC61 gamma chain), putative.	Uncharacterized protein.	0.745
TA04175	TA13100	Q4UC71	Q4UEC8	Protein translocation complex subunit (SEC61 gamma chain), putative.	Signal recognition particle receptor alpha subunit, putative.	0.768
TA04175	TA13480	Q4UC71	Q4UEJ6	Protein translocation complex subunit (SEC61 gamma chain), putative.	DNAJ-like sec63 homologue, putative.	0.978
TA04175	TA17425	Q4UC71	Q4UAV1	Protein translocation complex subunit (SEC61 gamma chain), putative.	Pre-protein translocase (SEC61 homologue), putative.	0.999
TA04175	TA18300	Q4UC71	Q4UAZ5	Protein translocation complex subunit (SEC61 gamma chain), putative.	Signal peptidase I.	0.454
TA04335	TA10130	Q4UC42	Q4U8T4	Uncharacterized protein.	Glycosyl transferase, putative.	0.594
TA04335	TA10705	Q4UC42	Q4U939	Uncharacterized protein.	Uncharacterized protein.	0.999