(51 nodes) Nucleic acid-binding, OB-fold network (Theileria annulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TA03865	Elong-fact-P_C domain-containing protein. (464 aa)
	TA17025	60S ribosomal protein L2/L8, putative. (258 aa)
	TA06205	Eukaryotic translation initiation factor 5A. (159 aa)
	TA06015	Eukaryotic translation initiation factor 2 alpha subunit, putative. (334 aa)
	TA05950	26S proteasome subunit 4, putative; Belongs to the AAA ATPase family. (438 aa)
	TA05825	Asparaginyl-tRNA synthetase (Chloroplast/mitochondrial), putative. (590 aa)
	TA06695	DNA replication licensing factor (MCM5 homologue), putative; Belongs to the MCM family. (770 aa)
	TA06255	26S proteasome subunit, putative; Belongs to the AAA ATPase family. (435 aa)
	TA02880	Minichromosome maintenance (MCM), putative; Belongs to the MCM family. (983 aa)
	TA03035	Elongation factor (Prokaryotic EFP homologue), putative. (153 aa)
	TA20515	DNA replication licensing factor Mcm2, putative; Belongs to the MCM family. (1019 aa)
	TA20525	Ribosomal protein s12, putative. (288 aa)
	TA20585	Exosome complex exonuclease rrp44, putative; Belongs to the RNR ribonuclease family. (955 aa)
	TA20915	Possible ribonuclease ii family protein. (1062 aa)
	TA21305	3'-5' exoribonuclease (CSL4 homologue), putative. (180 aa)
	TA21405	226S proteasome regulatory particle, putative; Belongs to the AAA ATPase family. (419 aa)
	TA19550	Rna-associated protein, putative. (690 aa)
	TA19535	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (145 aa)
	TA19500	DNA-directed RNA polymerase ii, putative. (175 aa)
	TA14970	Translation initiation factor eif-1A, putative; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (155 aa)
	TA15700	26S proteasome ATPase subunit (Rpt6A homologue), putative; Belongs to the AAA ATPase family. (393 aa)
	TA15415	Uncharacterized protein. (200 aa)
	TA14880	Asparaginyl-trna synthetase, putative. (704 aa)
	TA13680	DNA helicase. (903 aa)
	TA13200	Replication factor A-related protein, putative. (466 aa)
	TA12700	mRNA capping enzyme, putative. (421 aa)
	TA12390	40S ribosomal protein S11, putative; Belongs to the universal ribosomal protein uS17 family. (156 aa)
	TA11475	Methionine-trna ligase, putative. (350 aa)
	TA16080	Replication licensing factor, putative; Belongs to the MCM family. (1021 aa)
	TA15495	Replication protein A subunit. (625 aa)
	TA14785	ECR1_N domain-containing protein. (293 aa)
	TA11650	Uncharacterized protein. (308 aa)
	TA02595	Uncharacterized protein. (162 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (827 aa)
	TA03645	50S ribosomal protein L2, putative. (334 aa)
	TA03665	Uncharacterized protein. (275 aa)
	TA04275	Lysine--tRNA ligase. (470 aa)
	TA04505	40S ribosomal protein S28, putative. (67 aa)
	TA04845	Aspartyl-tRNA synthetase, putative. (629 aa)
	TA05175	DNA ligase. (899 aa)
	TA18610	Cold shock protein, putative. (95 aa)
	TA18035	40s ribosomal protein s23, putative; Belongs to the universal ribosomal protein uS12 family. (145 aa)
	TA17225	26s protease regulatory subunit, putative; Belongs to the AAA ATPase family. (396 aa)
	TA17345	DNA helicase; Belongs to the MCM family. (916 aa)
	TA09310	26S proteasome ATPase subunit, putative; Belongs to the AAA ATPase family. (448 aa)
	TA07425	Zf-primase domain-containing protein. (438 aa)
	TA08620	Lysyl t-RNA synthetase, putative. (679 aa)
	TA08800	DNA replication protein (MCM homologue), putative; Belongs to the MCM family. (945 aa)
	TA11015	S1 motif domain-containing protein. (953 aa)
	TA11085	Uncharacterized protein. (1059 aa)
	TA10305	Ribosomal protein S17, putative. (129 aa)

Your Current Organism:

Theileria annulata

NCBI taxonomy Id: 5874
Other names: T. annulata

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	TA02880	Q4UCK0	Q4UHJ8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Minichromosome maintenance (MCM), putative; Belongs to the MCM family.	0.984
MCM7	TA05175	Q4UCK0	Q4UBN2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA ligase.	0.713
MCM7	TA06695	Q4UCK0	Q4UHR0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA replication licensing factor (MCM5 homologue), putative; Belongs to the MCM family.	0.999
MCM7	TA07425	Q4UCK0	Q4UA61	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Zf-primase domain-containing protein.	0.996
MCM7	TA08800	Q4UCK0	Q4U9G0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA replication protein (MCM homologue), putative; Belongs to the MCM family.	0.982
MCM7	TA11650	Q4UCK0	Q4UD89	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.821
MCM7	TA13200	Q4UCK0	Q4UEE5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication factor A-related protein, putative.	0.766
MCM7	TA13680	Q4UCK0	Q4UEN3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase.	0.989
MCM7	TA15495	Q4UCK0	Q4UDF8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication protein A subunit.	0.766
MCM7	TA16080	Q4UCK0	Q4UDH3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication licensing factor, putative; Belongs to the MCM family.	0.990
MCM7	TA17345	Q4UCK0	Q4UAM8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	TA20515	Q4UCK0	Q4UH54	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA replication licensing factor Mcm2, putative; Belongs to the MCM family.	0.999
TA02595	TA04505	Q4UD22	Q4UC12	Uncharacterized protein.	40S ribosomal protein S28, putative.	0.501
TA02595	TA11015	Q4UD22	Q4U995	Uncharacterized protein.	S1 motif domain-containing protein.	0.768
TA02595	TA12390	Q4UD22	Q4UDZ8	Uncharacterized protein.	40S ribosomal protein S11, putative; Belongs to the universal ribosomal protein uS17 family.	0.500
TA02595	TA14785	Q4UD22	Q4UDE6	Uncharacterized protein.	ECR1_N domain-containing protein.	0.999
TA02595	TA18035	Q4UD22	Q4UB42	Uncharacterized protein.	40s ribosomal protein s23, putative; Belongs to the universal ribosomal protein uS12 family.	0.503
TA02595	TA19535	Q4UD22	Q4UGH4	Uncharacterized protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.404
TA02595	TA19550	Q4UD22	Q4UGH7	Uncharacterized protein.	Rna-associated protein, putative.	0.807
TA02595	TA20525	Q4UD22	Q4UH52	Uncharacterized protein.	Ribosomal protein s12, putative.	0.417