86 items (Theileria annulata) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	CRK3	Cyclin-dependent kinase CRK3 (CDK7 homologue), putative. (411 aa)
	MT-CO1	Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (480 aa)
	TA09705	DUF862 domain-containing protein. (365 aa)
	TA17090	Uncharacterized protein. (1764 aa)
	TA16825	Actin, putative; Belongs to the actin family. (468 aa)
	TA16805	DWNN domain-containing protein. (637 aa)
	TA06295	Uncharacterized protein. (687 aa)
	TA06230	Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (138 aa)
	TA06185	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (247 aa)
	TA02790	Cytochrome C oxidase subunit II (COX2 homologue), putative. (159 aa)
	TA20305	Transcription elongation factor, putative. (418 aa)
	TA20350	Membrane protein, putative. (460 aa)
	TA20675	Thioredoxin-like protein, putative. (214 aa)
	TA20705	Histone acetyltransferase gcn5-related, putative. (632 aa)
	TA21145	Genomic DNA chromosome 1 part 1. (516 aa)
	TA19355	Actin-related protein, putative; Belongs to the actin family. (538 aa)
	TA19240	Type ii proteins geranylgeranyltransferase beta subunit, putative. (404 aa)
	PIN1	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis/trans isomerase (PPIase) that acts as a key virulence factor by promoting host leukocyte transformation. Binds to and isomerizes specific phosphorylated Ser/Thr-Pro (pSer/Thr-Pro) motifs in a subset of proteins, resulting in conformational changes in the proteins. Promotes host leukocyte transformation by binding to phosphorylated host FBXW7, disrupting dimerization and promoting FBXW7 autoubiquitination and subsequent degradation. Degradation of host FBXW7, leads to stabilization of JUN, which promotes cell tr [...] (142 aa)
	TA20075	Cytochrome c oxidase assembly protein-like, putative. (285 aa)
	TA20025	Cytochrome c oxidase subunit 2a, putative. (262 aa)
	TA16035	Theileria-specific sub-telomeric protein, SVSP family, putative. (403 aa)
	TA15970	CTD-like phosphatase, putative. (767 aa)
	TA15345	Uncharacterized protein. (582 aa)
	TA15140	B box-type domain-containing protein. (250 aa)
	TA15125	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (2446 aa)
	TA14940	Uncharacterized protein. (307 aa)
	TA14685	Actin-related protein, putative; Belongs to the actin family. (451 aa)
	TA14115	14-3-3 protein homologue, putative; Belongs to the 14-3-3 family. (256 aa)
	TA13995	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (236 aa)
	TA13780	TAFII55_N domain-containing protein. (383 aa)
	TA13585	Chromatin-binding protein, putative. (470 aa)
	TA13565	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (875 aa)
	TA13555	Uncharacterized protein. (2471 aa)
	TA13310	Cell differentiation protein (RCD1 homologue), putative. (327 aa)
	TA13250	Uncharacterized protein. (556 aa)
	TA13230	Uncharacterized protein. (555 aa)
	TA13200	Replication factor A-related protein, putative. (466 aa)
	TA12555	Histone acetyltransferase, GCN5-like, putative. (391 aa)
	TA12515	Cyclin-dependent protein kinase, PHO85 homologue, putative. (524 aa)
	TA12095	Sco1/2-like protein, putative. (219 aa)
	TA12090	Protein kinase, putative. (208 aa)
	TA11845	1-phosphatidylinositol-4-phosphate 5-kinase. (776 aa)
	TA11795	Serine/threonine kinase, putative; Belongs to the protein kinase superfamily. (363 aa)
	TA15495	Replication protein A subunit. (625 aa)
	TA12915	Cytochrome c oxidase subunit, putative. (270 aa)
	TA12690	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (446 aa)
	TA12365	Thioredoxin, putative. (149 aa)
	TA02675	PUB domain-containing protein. (468 aa)
	TA02635	DNA-directed RNA polymerase II, putative. (124 aa)
	TA03190	NOT2_3_5 domain-containing protein. (181 aa)
	TA05285	TFIIS central domain-containing protein. (333 aa)
	TA04045	Glucose-6-phosphate isomerase; Belongs to the GPI family. (560 aa)
	TA04475	Uncharacterized protein. (165 aa)
	MED6	Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (214 aa)
	TA04900	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (345 aa)
	TA05220	Glucose-6-phosphate-1-dehydrogenase, putative. (878 aa)
	TA17590	Histone deacetylase family protein, putative. (1598 aa)
	TA18690	Uncharacterized protein. (1347 aa)
	TA17660	Ferrodoxin reductase-like protein, putative. (607 aa)
	TA17755	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (607 aa)
	TA17825	Serine/threonine kinase, putative. (638 aa)
	TA18115	SWIB domain-containing protein. (390 aa)
	TA18470	Serine/threonine-protein kinase, putative. (699 aa)
	TA07290	Histone H2B; Belongs to the histone H2B family. (123 aa)
	TA07780	Uncharacterized protein. (1228 aa)
	TA09185	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (490 aa)
	TA07275	Thioredoxin; Belongs to the thioredoxin family. (115 aa)
	TA07800	Transcription modulator, putative. (1026 aa)
	TA07815	Proteasome subunit, putative. (199 aa)
	TA08225	NOT2 / NOT3 / NOT5 family, putative. (273 aa)
	TA08265	Histone H2B; Belongs to the histone H2B family. (107 aa)
	TA08470	Cyclin-dependent serimne/threonine kinase (Cdk)-related protein, putative. (843 aa)
	TA08755	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (925 aa)
	TA08790	Uncharacterized protein. (1545 aa)
	TA08925	SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (468 aa)
	TA09110	Uncharacterized protein. (1429 aa)
	TA11030	mRNA turnover/deadenylation component (POP2 homologue), putative. (544 aa)
	TA10630	Casein kinase II subunit alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site (By similarity). (348 aa)
	TA10435	BSD domain-containing protein. (612 aa)
	TA10160	S27 ribosomal protein, putative. (162 aa)
	TA09960	Cell-cycle-related serine/threonine protein kinase, CDK homologue, putative. (548 aa)
	TA09890	Uncharacterized protein. (3595 aa)
	TA11340	RING-type domain-containing protein. (286 aa)
	TA11140	Rab geranylgeranyltransferase, putative. (667 aa)
	MT-CO3	Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (255 aa)
	CRK2	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity). (298 aa)

Your Current Organism:

Theileria annulata

NCBI taxonomy Id: 5874
Other names: T. annulata

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRK2	TA07290	Q26671	Q4UAL4	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	Histone H2B; Belongs to the histone H2B family.	0.474
CRK2	TA07815	Q26671	Q4U9Z1	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	Proteasome subunit, putative.	0.446
CRK2	TA08265	Q26671	Q4U9Q8	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	Histone H2B; Belongs to the histone H2B family.	0.474
CRK2	TA08755	Q26671	Q4U9G9	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.543
CRK2	TA09890	Q26671	Q4U8P1	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	Uncharacterized protein.	0.416
CRK2	TA10160	Q26671	Q4U8U0	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	S27 ribosomal protein, putative.	0.695
CRK2	TA11795	Q26671	Q4UDP1	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	Serine/threonine kinase, putative; Belongs to the protein kinase superfamily.	0.818
CRK2	TA12690	Q26671	Q4UDA7	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.434
CRK2	TA13200	Q26671	Q4UEE5	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	Replication factor A-related protein, putative.	0.593
CRK2	TA13230	Q26671	Q4UEF1	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	Uncharacterized protein.	0.751
CRK2	TA13250	Q26671	Q4UEF4	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	Uncharacterized protein.	0.751
CRK2	TA13565	Q26671	Q4UEL3	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.543
CRK2	TA14115	Q26671	Q4UEW2	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	14-3-3 protein homologue, putative; Belongs to the 14-3-3 family.	0.745
CRK2	TA14685	Q26671	Q4UF64	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	Actin-related protein, putative; Belongs to the actin family.	0.508
CRK2	TA15125	Q26671	Q4UFC0	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.792
CRK2	TA15495	Q26671	Q4UDF8	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	Replication protein A subunit.	0.593
CRK2	TA16825	Q26671	Q4UIK3	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	Actin, putative; Belongs to the actin family.	0.508
CRK2	TA17755	Q26671	Q4UB92	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.451
CRK2	TA18115	Q26671	Q4UB28	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	SWIB domain-containing protein.	0.424
CRK2	TA19355	Q26671	Q4UGE2	Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity).	Actin-related protein, putative; Belongs to the actin family.	0.508