13 items (Theileria annulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TA10535	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	TA08265	Histone H2B; Belongs to the histone H2B family. (107 aa)
	TA07845	Histone H2A; Belongs to the histone H2A family. (127 aa)
	TA07840	Histone H3; Belongs to the histone H3 family. (136 aa)
	TA07290	Histone H2B; Belongs to the histone H2B family. (123 aa)
	TA04740	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (681 aa)
	TA05395	Histone H3; Belongs to the histone H3 family. (136 aa)
	TA12910	Histone h3-like, putative. (324 aa)
	TA12985	Uncharacterized protein. (418 aa)
	TA14155	Histone H2A; Belongs to the histone H2A family. (152 aa)
	TA14555	CDC6-like ATPase, putative. (458 aa)
	TA15035	Uncharacterized protein. (2184 aa)
	TA19765	Origin recognition complex-like protein, putative. (509 aa)

Your Current Organism:

Theileria annulata

NCBI taxonomy Id: 5874
Other names: T. annulata

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TA04740	TA05395	Q4UBW0	Q4UCS5	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Histone H3; Belongs to the histone H3 family.	0.761
TA04740	TA07290	Q4UBW0	Q4UAL4	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Histone H2B; Belongs to the histone H2B family.	0.719
TA04740	TA07840	Q4UBW0	Q4U9Y6	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Histone H3; Belongs to the histone H3 family.	0.761
TA04740	TA07845	Q4UBW0	Q4U9Y5	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Histone H2A; Belongs to the histone H2A family.	0.709
TA04740	TA08265	Q4UBW0	Q4U9Q8	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Histone H2B; Belongs to the histone H2B family.	0.719
TA04740	TA10535	Q4UBW0	Q4U907	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.910
TA04740	TA12910	Q4UBW0	Q4UDB1	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Histone h3-like, putative.	0.761
TA04740	TA12985	Q4UBW0	Q4UEA6	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Uncharacterized protein.	0.964
TA04740	TA14155	Q4UBW0	Q4UEX0	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Histone H2A; Belongs to the histone H2A family.	0.640
TA04740	TA15035	Q4UBW0	Q4UFU6	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Uncharacterized protein.	0.964
TA04740	TA19765	Q4UBW0	Q4UFZ9	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Origin recognition complex-like protein, putative.	0.972
TA05395	TA04740	Q4UCS5	Q4UBW0	Histone H3; Belongs to the histone H3 family.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.761
TA05395	TA07290	Q4UCS5	Q4UAL4	Histone H3; Belongs to the histone H3 family.	Histone H2B; Belongs to the histone H2B family.	0.915
TA05395	TA07840	Q4UCS5	Q4U9Y6	Histone H3; Belongs to the histone H3 family.	Histone H3; Belongs to the histone H3 family.	0.501
TA05395	TA07845	Q4UCS5	Q4U9Y5	Histone H3; Belongs to the histone H3 family.	Histone H2A; Belongs to the histone H2A family.	0.936
TA05395	TA08265	Q4UCS5	Q4U9Q8	Histone H3; Belongs to the histone H3 family.	Histone H2B; Belongs to the histone H2B family.	0.915
TA05395	TA10535	Q4UCS5	Q4U907	Histone H3; Belongs to the histone H3 family.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.967
TA05395	TA12910	Q4UCS5	Q4UDB1	Histone H3; Belongs to the histone H3 family.	Histone h3-like, putative.	0.482
TA05395	TA14155	Q4UCS5	Q4UEX0	Histone H3; Belongs to the histone H3 family.	Histone H2A; Belongs to the histone H2A family.	0.938
TA05395	TA14555	Q4UCS5	Q4UF40	Histone H3; Belongs to the histone H3 family.	CDC6-like ATPase, putative.	0.761