(65 nodes) ATPases associated with a variety of cellular activities network (Theileria annulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TA20175	DEAD-box helicase, putative. (1925 aa)
	TA03020	DEAD-box family helicase, putative. (945 aa)
	TA03000	(Subtelomeric) ABC-transporter protein family member, putative. (1527 aa)
	TA02880	Minichromosome maintenance (MCM), putative; Belongs to the MCM family. (983 aa)
	TA06255	26S proteasome subunit, putative; Belongs to the AAA ATPase family. (435 aa)
	TA05950	26S proteasome subunit 4, putative; Belongs to the AAA ATPase family. (438 aa)
	TA06500	Transitional endoplasmic reticulum ATPase (CDC48 homologue), putative. (822 aa)
	TA04080	AAA family ATPase, putative; Belongs to the AAA ATPase family. (409 aa)
	TA04320	DEAD-box family helicase, putative. (1001 aa)
	TA04525	Replication factor, putative. (299 aa)
	TA04575	RuvB-like helicase; Belongs to the RuvB family. (492 aa)
	TA04740	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (681 aa)
	TA04855	Cell divison cycle CDC48 homologue, putative or transitional endoplasmic reticulum ATPase, putative. (905 aa)
	TA18495	Uncharacterized protein. (3913 aa)
	TA18630	Replication factor C subunit 1. (961 aa)
	TA17835	AAA family ATPase, putative. (557 aa)
	TA18045	U5 small nuclear ribonucleoprotein-specific helicase, putative. (2248 aa)
	TA17365	(Subtelomeric) ABC-transporter protein family member, putative. (1526 aa)
	TA05590	(Subtelomeric) ABC-transporter protein family member, putative. (1525 aa)
	TA17150	ABC transporter, putative. (1527 aa)
	TA17160	ABC transporter, putative. (1527 aa)
	TA17170	ABC transporter, putative. (1527 aa)
	TA17225	26s protease regulatory subunit, putative; Belongs to the AAA ATPase family. (396 aa)
	TA09310	26S proteasome ATPase subunit, putative; Belongs to the AAA ATPase family. (448 aa)
	TA07095	ClpB protein, putative. (1150 aa)
	TA07350	DNA repair (Rad51 homologue) protein, putative; Belongs to the RecA family. (369 aa)
	TA08130	Replication factor C subunit, putative. (347 aa)
	TA08135	ATPase_AAA_core domain-containing protein. (445 aa)
	TA08725	Metallopeptidase, putative; Belongs to the AAA ATPase family. (691 aa)
	TA10790	Replication factor C, putative. (840 aa)
	TA10610	RuvB-like helicase; Belongs to the RuvB family. (494 aa)
	TA09910	Endopeptidase (CLP homologue) ATP-binding chain, putative. (916 aa)
	TA11220	RNAse L inhibitor protein, putative. (636 aa)
	TA10970	AAA domain-containing protein. (788 aa)
	TA10030	(Subtelomeric) ABC-transporter protein family member, putative. (1709 aa)
	TA06625	ATP binding protein (Maybe ABC transporter), putative. (937 aa)
	TA13125	Mitochondrial respiratory chain complexes assembly protein (AFG3 homologue), putative. (818 aa)
	TA16350	Replication factor C subunit (RPC2 homologue), putative. (336 aa)
	TA12925	(Subtelomeric) ABC-transporter family member, putative. (1563 aa)
	TA12920	(Subtelomeric) ABC-transporter protein family member, putative. (1527 aa)
	TA12900	(Subtelomeric) ABC-transporter protein family member, putative. (1539 aa)
	TA12745	Lon protease homolog 2, mitochondrial, putative; Belongs to the peptidase S16 family. (1103 aa)
	TA11700	N-ethylmaleimide-sensitive factor, putative. (711 aa)
	TA13575	Aaa family ATPase, putative. (881 aa)
	TA11425	ABC-transporter protein family, putative. (1527 aa)
	TA17350	(Subtelomeric) ABC-transporter protein family member, putative. (1526 aa)
	TA02730	ABC transporter, putative. (1491 aa)
	TA02720	ABC protein, putative. (1525 aa)
	TA05455	ABC transporter, putative. (1652 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (827 aa)
	TA16855	DEAD-box family helicase, putative. (729 aa)
	TA16460	Metalloprotease/cell division cycle protein (FtsH homologue), putative. (805 aa)
	TA16645	ATPase, putative. (719 aa)
	TA13290	ABC transporter protein, putative. (722 aa)
	TA13680	DNA helicase. (903 aa)
	TA14825	MDR-family, ABC transporter, putative. (743 aa)
	TA15700	26S proteasome ATPase subunit (Rpt6A homologue), putative; Belongs to the AAA ATPase family. (393 aa)
	TA15825	26S protease subunit, putative; Belongs to the AAA ATPase family. (634 aa)
	TA15955	(Subtelomeric) ABC-transporter protein family member, putative. (1511 aa)
	TA16015	(Subtelomeric) ABC-transporter protein family member, putative. (1516 aa)
	TA19175	ABC transporter protein, putative. (1525 aa)
	TA19645	ABC transporter, putative. (650 aa)
	TA21405	226S proteasome regulatory particle, putative; Belongs to the AAA ATPase family. (419 aa)
	TA20945	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (583 aa)
	TA20515	DNA replication licensing factor Mcm2, putative; Belongs to the MCM family. (1019 aa)

Your Current Organism:

Theileria annulata

NCBI taxonomy Id: 5874
Other names: T. annulata

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	TA02880	Q4UCK0	Q4UHJ8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Minichromosome maintenance (MCM), putative; Belongs to the MCM family.	0.984
MCM7	TA04525	Q4UCK0	Q4UC08	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication factor, putative.	0.778
MCM7	TA04740	Q4UCK0	Q4UBW0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.967
MCM7	TA07350	Q4UCK0	Q4UA75	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA repair (Rad51 homologue) protein, putative; Belongs to the RecA family.	0.411
MCM7	TA08130	Q4UCK0	Q4U9T3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication factor C subunit, putative.	0.797
MCM7	TA10790	Q4UCK0	Q4U954	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication factor C, putative.	0.617
MCM7	TA13680	Q4UCK0	Q4UEN3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase.	0.989
MCM7	TA16350	Q4UCK0	Q4UIH2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication factor C subunit (RPC2 homologue), putative.	0.805
MCM7	TA18630	Q4UCK0	Q4UBG2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication factor C subunit 1.	0.485
MCM7	TA20515	Q4UCK0	Q4UH54	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA replication licensing factor Mcm2, putative; Belongs to the MCM family.	0.999
MCM7	TA20945	Q4UCK0	Q4UGW6	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.549
TA02720	TA04855	Q4UD47	Q4UBT9	ABC protein, putative.	Cell divison cycle CDC48 homologue, putative or transitional endoplasmic reticulum ATPase, putative.	0.538
TA02720	TA05950	Q4UD47	Q4UI30	ABC protein, putative.	26S proteasome subunit 4, putative; Belongs to the AAA ATPase family.	0.493
TA02720	TA06255	Q4UD47	Q4UHP7	ABC protein, putative.	26S proteasome subunit, putative; Belongs to the AAA ATPase family.	0.493
TA02720	TA06500	Q4UD47	Q4UID0	ABC protein, putative.	Transitional endoplasmic reticulum ATPase (CDC48 homologue), putative.	0.538
TA02720	TA08135	Q4UD47	Q4U9T2	ABC protein, putative.	ATPase_AAA_core domain-containing protein.	0.487
TA02720	TA09310	Q4UD47	Q4UAE5	ABC protein, putative.	26S proteasome ATPase subunit, putative; Belongs to the AAA ATPase family.	0.400
TA02720	TA11700	Q4UD47	Q4UDM4	ABC protein, putative.	N-ethylmaleimide-sensitive factor, putative.	0.502
TA02720	TA13290	Q4UD47	Q4UEG2	ABC protein, putative.	ABC transporter protein, putative.	0.494
TA02720	TA13575	Q4UD47	Q4UDC4	ABC protein, putative.	Aaa family ATPase, putative.	0.538