(42 nodes) RNA degradation network (Theileria annulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TA10140	Uncharacterized protein. (332 aa)
	TA10425	Enolase, putative. (442 aa)
	TA10935	Uncharacterized protein. (378 aa)
	TA11030	mRNA turnover/deadenylation component (POP2 homologue), putative. (544 aa)
	TA08755	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (925 aa)
	TA08225	NOT2 / NOT3 / NOT5 family, putative. (273 aa)
	TA08085	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (937 aa)
	TA08050	DEAD-family helicase, putative. (1069 aa)
	TA07745	U6 snRNP protein Lsm2, putative. (112 aa)
	TA07065	Chaperonin (HSP60), putative; Belongs to the chaperonin (HSP60) family. (583 aa)
	TA17980	U6 snrna-associated sm-like protein, putative. (87 aa)
	LSM4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (105 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (113 aa)
	TA04265	3'-5' exonuclease, putative. (790 aa)
	TA03350	Chaperonin CPN60, putative; Belongs to the chaperonin (HSP60) family. (639 aa)
	TA03190	NOT2_3_5 domain-containing protein. (181 aa)
	TA02540	Nudix hydrolase domain-containing protein. (341 aa)
	TA02595	Uncharacterized protein. (162 aa)
	TA14785	ECR1_N domain-containing protein. (293 aa)
	LSM3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (94 aa)
	TA11675	5'-3' exoribonuclease 2, putative. (1467 aa)
	TA12470	Topoisomerase-related nucleotidyltransferase, putative. (532 aa)
	TA13280	Exonuclease, putative. (1120 aa)
	TA13310	Cell differentiation protein (RCD1 homologue), putative. (327 aa)
	TA13555	Uncharacterized protein. (2471 aa)
	TA13610	ATP-dependent RNA helicase, putative. (1027 aa)
	TA14185	ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family. (416 aa)
	TA14515	R3H domain-containing protein. (623 aa)
	TA14920	Heat shock protein HSP70 homologue, putative; Belongs to the heat shock protein 70 family. (681 aa)
	TA19335	Exosome complex exonuclease, putative. (322 aa)
	TA21305	3'-5' exoribonuclease (CSL4 homologue), putative. (180 aa)
	TA21145	Genomic DNA chromosome 1 part 1. (516 aa)
	TA20905	Exosome complex exonuclease rrp41, putative. (245 aa)
	TA20585	Exosome complex exonuclease rrp44, putative; Belongs to the RNR ribonuclease family. (955 aa)
	LSM5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (90 aa)
	TA05935	5'-3' exoribonuclease (XRN2, DHM1 homologue), putative. (619 aa)
	TA06285	Exosome ribonuclease PH (Rrp42 homologue), putative. (268 aa)
	TA06325	Exosome complex exonuclease (Rrp46 homologue), putative. (265 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (161 aa)
	TA06545	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (664 aa)
	TA16725	U6 snRNA-associated Sm-lke protein, putative. (76 aa)
	TA17090	Uncharacterized protein. (1764 aa)

Your Current Organism:

Theileria annulata

NCBI taxonomy Id: 5874
Other names: T. annulata

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSM1	LSM3	Q4UID3	Q4UDG7	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.999
LSM1	LSM4	Q4UID3	Q4UBR6	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.999
LSM1	LSM5	Q4UID3	Q4UHZ4	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	0.999
LSM1	LSM8	Q4UID3	Q4UC24	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.995
LSM1	TA02540	Q4UID3	Q4UD11	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	Nudix hydrolase domain-containing protein.	0.947
LSM1	TA05935	Q4UID3	Q4UI27	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	5'-3' exoribonuclease (XRN2, DHM1 homologue), putative.	0.901
LSM1	TA06545	Q4UID3	Q4UID9	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.606
LSM1	TA07745	Q4UID3	Q4UA02	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	U6 snRNP protein Lsm2, putative.	0.999
LSM1	TA08050	Q4UID3	Q4U9U7	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	DEAD-family helicase, putative.	0.637
LSM1	TA08085	Q4UID3	Q4U9U2	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.461
LSM1	TA10140	Q4UID3	Q4U8T6	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	Uncharacterized protein.	0.901
LSM1	TA11030	Q4UID3	Q4U997	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	mRNA turnover/deadenylation component (POP2 homologue), putative.	0.402
LSM1	TA11675	Q4UID3	Q4UDL9	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	5'-3' exoribonuclease 2, putative.	0.901
LSM1	TA13280	Q4UID3	Q4UEG0	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	Exonuclease, putative.	0.419
LSM1	TA14185	Q4UID3	Q4UEX3	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	0.999
LSM1	TA16725	Q4UID3	Q4UII3	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	U6 snRNA-associated Sm-lke protein, putative.	0.999
LSM1	TA17980	Q4UID3	Q4UB53	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	U6 snrna-associated sm-like protein, putative.	0.999
LSM3	LSM1	Q4UDG7	Q4UID3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	0.999
LSM3	LSM4	Q4UDG7	Q4UBR6	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.999
LSM3	LSM5	Q4UDG7	Q4UHZ4	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	0.999