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| | rne | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1077 aa) |
| | rsmG | 16S rRNA methyltransferase; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (214 aa) |
| | mnmG | tRNA uridine 5-carboxymethylaminomethyl modification protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (630 aa) |
| | mnmE | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (456 aa) |
| | rnpA | Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (65 aa) |
| | glyS | glycyl-tRNA synthetase; TIGRFAM: glyS: glycine--tRNA ligase, beta subunit; PRINTS: Glycyl-tRNA synthetase beta subunit signature; Pfam: Glycyl-tRNA synthetase beta subunit. (684 aa) |
| | glyQ | Pfam: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glyQ: glycine--tRNA ligase, alpha subunit; PRINTS: Glycyl-tRNA synthetase alpha subunit signature. (317 aa) |
| | AKA27503.1 | 16S rRNA methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (441 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (319 aa) |
| | tsaC | tRNA threonylcarbamoyladenosine biosynthesis protein RimN; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. (185 aa) |
| | AKA27490.1 | LysR family transcriptional regulator; TIGRFAM: chol_sulf_TF: putative choline sulfate-utilization transcription factor; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (316 aa) |
| | AKA27484.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (297 aa) |
| | AKA27403.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (299 aa) |
| | AKA27397.1 | TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family; Pfam: Sigma-70 region 2; Pfam: Sigma-70, region 4. (166 aa) |
| | AKA27370.1 | Hypothetical protein; Pfam: NYN domain. (229 aa) |
| | AKA27364.1 | prolyl-tRNA synthetase; Pfam: Aminoacyl-tRNA editing domain. (151 aa) |
| | AKA27347.1 | TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family; Pfam: Sigma-70, region 4; Pfam: Sigma-70 region 2. (204 aa) |
| | AKA27339.1 | TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family; Pfam: Sigma-70, region 4. (179 aa) |
| | AKA27296.1 | CMP deaminase; Pfam: Cytidine and deoxycytidylate deaminase zinc-binding region. (153 aa) |
| | AKA27261.1 | Transcriptional regulator; Pfam: LysR substrate binding domain; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Belongs to the LysR transcriptional regulatory family. (290 aa) |
| | vapC-2 | Plasmid stability protein StbB; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (142 aa) |
| | trmL | RNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (151 aa) |
| | thiI | tRNA s(4)U8 sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (484 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (145 aa) |
| | AKA27111.1 | 16S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (235 aa) |
| | argS | Pfam: tRNA synthetases class I (R); TIGRFAM: argS: arginine--tRNA ligase; SMART: DALR anticodon binding domain; Pfam: DALR anticodon binding domain; Pfam: Arginyl tRNA synthetase N terminal domain; PRINTS: Arginyl-tRNA synthetase signature; SMART: Arginyl tRNA synthetase N terminal dom. (578 aa) |
| | priA | Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (739 aa) |
| | rlmJ | Protein involved in catabolism of external DNA; Specifically methylates the adenine in position 2030 of 23S rRNA. (278 aa) |
| | orn | Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (180 aa) |
| | queG | Putative iron-sulfur cluster-binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (359 aa) |
| | AKA26973.1 | ATPase; TIGRFAM: T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE; Pfam: Uncharacterised P-loop hydrolase UPF0079. (156 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (323 aa) |
| | rnr | Exoribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (868 aa) |
| | rlmB | 23S rRNA (guanosine-2'-O-)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. (255 aa) |
| | dnaB | DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (465 aa) |
| | AKA26942.1 | Pfam: LysR substrate binding domain; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; PRINTS: LysR bacterial regulatory protein HTH signature; Belongs to the LysR transcriptional regulatory family. (301 aa) |
| | AKA26922.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (303 aa) |
| | dusB | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. (337 aa) |
| | cmoM | SmtA protein; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family. (249 aa) |
| | AKA26819.1 | Pfam: LysR substrate binding domain; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Belongs to the LysR transcriptional regulatory family. (309 aa) |
| | AKA26769.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (303 aa) |
| | AKA26723.1 | RNA-binding protein; SMART:; Pfam: CRS1 / YhbY (CRM) domain. (102 aa) |
| | rlmE | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (209 aa) |
| | nusA | Peptidase M54; Participates in both transcription termination and antitermination. (493 aa) |
| | rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (131 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (305 aa) |
| | pnp | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (701 aa) |
| | AKA26638.1 | Ribonuclease G; SMART: Ribosomal protein S1-like RNA-binding domain; TIGRFAM: RNaseEG: ribonuclease, Rne/Rng family; Pfam: S1 RNA binding domain; Pfam: Ribonuclease E/G family. (485 aa) |
| | AKA26623.1 | RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (489 aa) |
| | AKA26557.1 | Pfam: LysR substrate binding domain; PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Belongs to the LysR transcriptional regulatory family. (316 aa) |
| | AKA26551.1 | RNA polymerase sigma factor; Pfam: Sigma-70 region 2; Pfam: Sigma-70, region 4; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family. (162 aa) |
| | rhlB | RNA helicase; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (490 aa) |
| | rlmF | 16S rRNA methyltransferase; Specifically methylates the adenine in position 1618 of 23S rRNA. (341 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (948 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (225 aa) |
| | rimM | 16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (178 aa) |
| | trmD | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (199 aa) |
| | lysS | PRINTS: Lysyl-tRNA synthetase signature; Pfam: OB-fold nucleic acid binding domain; Pfam: tRNA synthetases class II (D, K and N); TIGRFAM: lysS_bact: lysine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family. (508 aa) |
| | AKA26411.1 | Pfam: Bacterial regulatory proteins, tetR family. (238 aa) |
| | AKA26401.1 | Universal bacterial protein YeaZ; TIGRFAM: T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ; Pfam: Glycoprotease family. (224 aa) |
| | rsmJ | SAM-dependent methyltransferase; Specifically methylates the guanosine in position 1516 of 16S rRNA. (281 aa) |
| | AKA26382.1 | Dinucleotide-utilizing enzyme; Pfam: ThiF family; possibly involved in molybdopterin or thiamin biosynthesis. (256 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (210 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (442 aa) |
| | truD | tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (352 aa) |
| | rpoS | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. (334 aa) |
| | AKA26291.1 | Hypothetical protein; Pfam: DTW domain. (236 aa) |
| | AKA26286.1 | Pfam: Uncharacterised protein family UPF0066; TIGRFAM: YaeB_AF0241: putative methyltransferase, YaeB/AF_0241 family. (231 aa) |
| | AKA26284.1 | Pfam: S4 domain; SMART: S4 RNA-binding domain. (236 aa) |
| | rimO | Ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (445 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (571 aa) |
| | AKA26236.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (302 aa) |
| | AKA26167.1 | RNA polymerase sigma factor; Pfam: Sigma-70, region 4; Pfam: Sigma-70 region 2; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family. (179 aa) |
| | AKA26166.1 | Hypothetical protein; Pfam: Domain of unknown function (DUF1508). (111 aa) |
| | AKA26128.1 | SMART: S4 RNA-binding domain; TIGRFAM: TIGR00093: pseudouridine synthase; Pfam: RNA pseudouridylate synthase; Pfam: S4 domain; Belongs to the pseudouridine synthase RsuA family. (230 aa) |
| | rpoE | TIGRFAM: RpoE_Sigma70: RNA polymerase sigma factor RpoE; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family; Pfam: Sigma-70 region 2; Pfam: Sigma-70, region 4. (193 aa) |
| | rnd | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (377 aa) |
| | AKA26072.1 | 23S rRNA methyltransferase; Pfam: SpoU rRNA Methylase family. (155 aa) |
| | AKA26034.1 | RNA helicase; SMART: DEAD-like helicases superfamily; SMART: Helicase associated domain (HA2) Add an annotation; SMART: ATPases associated with a variety of cellular activities; Pfam: Oligonucleotide/oligosaccharide-binding (OB)-fold; Pfam: DEAD/DEAH box helicase; Pfam: Domain of unknown function (DUF3418); Pfam: Helicase conserved C-terminal domain; TIGRFAM: DEAH_box_HrpA: ATP-dependent helicase HrpA; SMART: helicase superfamily c-terminal domain; Pfam: Helicase associated domain (HA2). (1303 aa) |
| | AKA26031.1 | RNA polymerase subunit sigma-24; Pfam: Sigma-70, region 4; Pfam: Sigma-70 region 2; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family. (204 aa) |
| | AKA25994.1 | Hypothetical protein; Pfam: DTW domain. (206 aa) |
| | AKA25966.1 | Phosphoesterase; SMART: DNA polymerase alpha chain like domain; Pfam: PHP domain. (287 aa) |
| | AKA25965.1 | Translation factor Sua5; TIGRFAM: TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family; Pfam: Telomere recombination; Belongs to the SUA5 family. (209 aa) |
| | AKA25962.1 | Ribosomal large subunit pseudouridine synthase B; Pfam: RNA pseudouridylate synthase; TIGRFAM: TIGR00093: pseudouridine synthase; Pfam: S4 domain; SMART: S4 RNA-binding domain; Belongs to the pseudouridine synthase RsuA family. (407 aa) |
| | AKA25955.1 | RNA helicase; Pfam: Domain of unknown function (DUF927). (595 aa) |
| | AKA25954.1 | Topoisomerase; Pfam: Toprim domain. (261 aa) |
| | AKA25914.1 | SMART: ATPases associated with a variety of cellular activities; Pfam: Flagellar regulatory protein FleQ; Pfam: Sigma-54 interaction domain; PRINTS: FIS bacterial regulatory protein HTH signature; Pfam: Bacterial regulatory protein, Fis family. (491 aa) |
| | fliA | RNA polymerase sigma 70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (246 aa) |
| | AKA25865.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (297 aa) |
| | AKA25842.1 | methionyl-tRNA formyltransferase; Pfam: Formyl transferase. (200 aa) |
| | AKA25773.1 | Pfam: tRNA synthetases class II (A); Pfam: Threonyl and Alanyl tRNA synthetase second additional domain. (208 aa) |
| | AKA25772.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (327 aa) |
| | rluC | 23S rRNA pseudouridylate synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (319 aa) |
| | AKA25725.1 | Termination factor Rho. (126 aa) |
| | AKA25721.1 | Phosphohydrolase; SMART: Metal dependent phosphohydrolases with conserved 'HD' motif; Pfam: HD domain. (215 aa) |
| | AKA25635.1 | PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (307 aa) |
| | sigX | RNA polymerase sigma factor SigX; Pfam: Sigma-70, region 4; Pfam: Sigma-70 region 2; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family. (128 aa) |
| | rlmL | 23S rRNA methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. (753 aa) |
| | rlmM | 23S rRNA methyltransferase; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. (356 aa) |
| | tusA | Sulfurtransferase; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. (83 aa) |
| | dusA | tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (312 aa) |
| | AKA25499.1 | Hypothetical protein; Pfam: Bifunctional DNA primase/polymerase, N-terminal; SMART: Bifunctional DNA primase/polymerase, N-terminal. (852 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (493 aa) |
| | dusC | tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. (319 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (274 aa) |
| | csrA-2 | Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (64 aa) |
| | thrS-2 | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (640 aa) |
| | pheS | Pfam: Aminoacyl tRNA synthetase class II, N-terminal domain; Pfam: tRNA synthetases class II core domain (F); TIGRFAM: pheS: phenylalanine--tRNA ligase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (338 aa) |
| | pheT | phenylalanyl-tRNA synthetase; SMART: Ferredoxin-fold anticodon binding domain; Pfam: Putative tRNA binding domain; SMART: tRNA synthetase B5 domain; Pfam: B3/4 domain; Pfam: Ferredoxin-fold anticodon binding domain; SMART: B3/4 domain; Pfam: tRNA synthetase B5 domain; TIGRFAM: pheT_bact: phenylalanine--tRNA ligase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (792 aa) |
| | selU | tRNA 2-selenouridine synthase; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2- selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain. (367 aa) |
| | AKA25299.1 | RtcB family protein; Pfam: tRNA-splicing ligase RtcB. (408 aa) |
| | rtcA | RNA 3'-terminal-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (353 aa) |
| | AKA25265.1 | Pfam: Sigma-70 region 2; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family; Pfam: Sigma-70, region 4. (168 aa) |
| | AKA25232.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (314 aa) |
| | AKA25228.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (308 aa) |
| | AKA25197.1 | Hypothetical protein. (359 aa) |
| | AKA25177.1 | PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain. (291 aa) |
| | AKA25100.1 | RNA polymerase subunit sigma24; Pfam: Sigma-70, region 4; Pfam: Sigma-70 region 2; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family. (315 aa) |
| | AKA25005.1 | Hypothetical protein; Pfam: tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE). (53 aa) |
| | AKA24997.1 | Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA; Pfam: tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE). (184 aa) |
| | AKA24955.1 | Pfam: Formyl transferase. (275 aa) |
| | AKA24857.1 | Pfam: Ribonuclease T2 family; Belongs to the RNase T2 family. (218 aa) |
| | AKA24835.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (303 aa) |
| | rnhA | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (150 aa) |
| | AKA24768.1 | Hydroxyglutarate oxidase; Pfam: FAD dependent oxidoreductase. (397 aa) |
| | AKA24757.1 | Pfam: Sigma-70, region 4; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family. (181 aa) |
| | AKA24655.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (299 aa) |
| | AKA24642.1 | Pfam: LysR substrate binding domain; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Belongs to the LysR transcriptional regulatory family. (292 aa) |
| | AKA24603.1 | Phenylacetic acid degradation protein; Pfam: PaaX-like protein; Pfam: PaaX-like protein C-terminal domain; TIGRFAM: PaaX_trns_reg: phenylacetic acid degradation operon negative regulatory protein PaaX. (297 aa) |
| | AKA24580.1 | ATP-dependent DNA ligase; TIGRFAM: ligD_pol: DNA polymerase LigD, polymerase domain; TIGRFAM: LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain; TIGRFAM: NHEJ_ligase_prk: DNA ligase D; Pfam: Eukaryotic and archaeal DNA primase small subunit; Pfam: DNA polymerase Ligase (LigD); TIGRFAM: NHEJ_ligase_lig: DNA polymerase LigD, ligase domain; Pfam: ATP dependent DNA ligase C terminal region; Pfam: ATP dependent DNA ligase domain. (869 aa) |
| | AKA24487.1 | Pfam: LysR substrate binding domain; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Belongs to the LysR transcriptional regulatory family. (299 aa) |
| | AKA24436.1 | Pfam: Acetyltransferase (GNAT) domain; Pfam: Rnk N-terminus; Pfam: Transcription elongation factor, GreA/GreB, C-term. (320 aa) |
| | AKA24356.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (300 aa) |
| | AKA24353.1 | Pyocin; Pfam: S-type Pyocin. (460 aa) |
| | AKA24330.1 | Pfam: Sigma-70, region 4; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family; Pfam: Sigma-70 region 2. (139 aa) |
| | AKA24246.1 | PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: LysR substrate binding domain; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family. (297 aa) |
| | AKA24140.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (299 aa) |
| | AKA24116.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain. (304 aa) |
| | AKA24077.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (298 aa) |
| | AKA23944.1 | Hypothetical protein. (593 aa) |
| | AKA23941.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain. (305 aa) |
| | AKA23901.1 | RNA polymerase sigma factor; Pfam: Sigma-70, region 4; Pfam: Sigma-70 region 2; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family. (170 aa) |
| | AKA23837.1 | Sulfurtransferase; Pfam: DsrE/DsrF-like family; TIGRFAM: sulf_tusD_dsrE: sulfur relay protein TusD/DsrE. (130 aa) |
| | AKA23836.1 | TIGRFAM: sulf_tusC_dsrF: sulfur relay protein TusC/DsrF; Pfam: DsrE/DsrF-like family; Belongs to the DsrF/TusC family. (120 aa) |
| | AKA23835.1 | TIGRFAM: sulf_tusB_dsrH: sulfur relay protein TusB/DsrH; Pfam: DsrH like protein. (99 aa) |
| | AKA23834.1 | Sulfurtransferase; Part of a sulfur-relay system. (111 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa) |
| | mnmA | tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (374 aa) |
| | AKA23796.1 | Toxin. (116 aa) |
| | AKA23786.1 | Twitching motility protein PilT; Pfam: PIN domain. (125 aa) |
| | cysS | Pfam: tRNA synthetases class I (C) catalytic domain; TIGRFAM: cysS: cysteine--tRNA ligase; SMART:; Pfam: DALR domain; PRINTS: Cysteinyl-tRNA synthetase signature; Belongs to the class-I aminoacyl-tRNA synthetase family. (460 aa) |
| | glnS | Pfam: tRNA synthetases class I (E and Q), anti-codon binding domain; TIGRFAM: glnS: glutamine--tRNA ligase; Pfam: tRNA synthetases class I (E and Q), catalytic domain; PRINTS: Glutamyl-tRNA synthetase signature. (565 aa) |
| | AKA23773.1 | Hypothetical protein; Pfam: Domain of unknown function (DUF1508). (110 aa) |
| | AKA23754.1 | Pfam: Sigma-70, region 4; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family; Pfam: Sigma-70 region 2. (168 aa) |
| | AKA23727.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (299 aa) |
| | AKA23665.1 | RNA polymerase subunit sigma-24; Pfam: Sigma-70, region 4; Pfam: Sigma-70 region 2; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family. (166 aa) |
| | AKA23636.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (301 aa) |
| | AKA23631.1 | SAM-dependent methyltransferase PhcB; Pfam: Methyltransferase domain. (348 aa) |
| | AKA23630.1 | SAM-dependent methyltransferase PhcB. (48 aa) |
| | AKA23629.1 | SAM-dependent methyltransferase PhcB. (52 aa) |
| | AKA23627.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain; PRINTS: LysR bacterial regulatory protein HTH signature. (306 aa) |
| | AKA23589.1 | SAM-dependent methyltransferase; Pfam: Family of unknown function (DUF633). (224 aa) |
| | AKA23579.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain; PRINTS: LysR bacterial regulatory protein HTH signature; Belongs to the LysR transcriptional regulatory family. (297 aa) |
| | AKA23555.1 | RNA polymerase sigma factor; Pfam: Sigma-70, region 4; Pfam: Sigma-70 region 2; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family. (159 aa) |
| | AKA23504.1 | Hypothetical protein; TIGRFAM: release_rtcB: release factor H-coupled RctB family protein; Pfam: tRNA-splicing ligase RtcB. (377 aa) |
| | AKA23430.1 | RNA polymerase sigma70; Pfam: Sigma-70 region 2; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family; Pfam: Sigma-70, region 4. (182 aa) |
| | AKA23408.1 | Pfam: RNA pseudouridylate synthase. (296 aa) |
| | deaD | RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (556 aa) |
| | AKA23303.1 | Hypothetical protein; SMART: Rhodanese Homology Domain; Pfam: Rhodanese-like domain; Belongs to the UPF0176 family. (313 aa) |
| | AKA23302.1 | BolA family transcriptional regulator; Pfam: BolA-like protein; Belongs to the BolA/IbaG family. (99 aa) |
| | mnmC | FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. (665 aa) |
| | AKA23250.1 | Ribosomal large subunit pseudouridine synthase A; Pfam: RNA pseudouridylate synthase. (211 aa) |
| | rlmD | 23S rRNA methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (432 aa) |
| | ttcA | Putative ATPase of the PP-loop superfamily implicated in cell cycle control; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (274 aa) |
| | AKA23139.1 | Pfam: Formyl transferase; Pfam: Ankyrin repeats (3 copies); SMART: ankyrin repeats. (392 aa) |
| | csrA | Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (62 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (874 aa) |
| | AKA23076.1 | RNA polymerase subunit sigma-24; Pfam: Sigma-70, region 4; Pfam: Sigma-70 region 2; Pfam: Tetratricopeptide repeat; Belongs to the sigma-70 factor family. (416 aa) |
| | AKA23063.1 | Pfam: LysR substrate binding domain; PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family. (321 aa) |
| | AKA23047.1 | RNA polymerase sigma factor; Pfam: Sigma-70 region 2; Pfam: Sigma-70, region 4; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family. (173 aa) |
| | AKA23009.1 | RNA polymerase subunit sigma-24; Pfam: Sigma-70 region 2; Pfam: Sigma-70, region 4; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family. (172 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (558 aa) |
| | AKA22923.1 | Pfam: Exonuclease; Pfam: Exonuclease C-terminal; SMART:. (476 aa) |
| | AKA22897.1 | Pfam: LysR substrate binding domain; PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Belongs to the LysR transcriptional regulatory family. (295 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (683 aa) |
| | rnt | Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (224 aa) |
| | AKA22840.1 | Hypothetical protein; Pfam: Aminoacyl-tRNA editing domain; TIGRFAM: YbaK_EbsC: Cys-tRNA(Pro) deacylase; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (156 aa) |
| | cmoA | rRNA cytosine-C5-methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). (247 aa) |
| | cmoB | tRNA methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. (318 aa) |
| | tadA | Zinc-binding protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (164 aa) |
| | hisS | histidyl-tRNA synthetase; Pfam: Anticodon binding domain; Pfam: Histidyl-tRNA synthetase; TIGRFAM: hisS: histidine--tRNA ligase. (429 aa) |
| | AKA22761.1 | cro/Cl family transcriptional regulator; SMART: Helix-turn-helix XRE-family like proteins; Pfam: Helix-turn-helix domain; Pfam: Domain of unknown function (DUF4115). (339 aa) |
| | rlmN | 50S rRNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (382 aa) |
| | trmJ | RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (259 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (377 aa) |
| | AKA22735.1 | Hypothetical protein; Pfam: Toprim domain. (325 aa) |
| | AKA22734.1 | Pfam: Protein of unknown function (DUF3631). (448 aa) |
| | vapC | Pirin; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (69 aa) |
| | rsmH | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (315 aa) |
| | rsmI | 16S rRNA methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (290 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (451 aa) |
| | rsmC | 16S rRNA methyltransferase; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. (332 aa) |
| | AKA22561.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (312 aa) |
| | AKA22539.1 | PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: LysR substrate binding domain; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Belongs to the LysR transcriptional regulatory family. (301 aa) |
| | AKA22532.1 | Putative positive regulator of gcv operon; PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: LysR substrate binding domain; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family. (308 aa) |
| | AKA22515.1 | PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: LysR substrate binding domain; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Belongs to the LysR transcriptional regulatory family. (308 aa) |
| | AKA22512.1 | Pfam: LysR substrate binding domain; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Belongs to the LysR transcriptional regulatory family. (305 aa) |
| | gluQ | glutamyl-Q tRNA(Asp) ligase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (298 aa) |
| | pcnB | poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (467 aa) |
| | AKA22440.1 | Pfam: S-adenosylmethionine-dependent methyltransferase; Belongs to the methyltransferase superfamily. (338 aa) |
| | AKA22409.1 | 23S rRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (320 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (943 aa) |
| | AKA22373.1 | Pfam: Transcription elongation factor, GreA/GreB, C-term. (164 aa) |
| | rlmG | 50S rRNA methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (374 aa) |
| | trmA | tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). (359 aa) |
| | AKA22316.1 | DEAD/DEAH box helicase; Pfam: Helicase conserved C-terminal domain; SMART: DEAD-like helicases superfamily; SMART: helicase superfamily c-terminal domain; Pfam: DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. (444 aa) |
| | AKA22310.1 | Nuclease; Pfam: NYN domain. (159 aa) |
| | AKA22306.1 | Pfam: Helicase conserved C-terminal domain; SMART: Helicase associated domain (HA2) Add an annotation; Pfam: Helicase associated domain (HA2); SMART: helicase superfamily c-terminal domain; TIGRFAM: DEAH_box_HrpB: ATP-dependent helicase HrpB; SMART: DEAD-like helicases superfamily; Pfam: ATP-dependent helicase C-terminal; Pfam: DEAD/DEAH box helicase. (843 aa) |
| | AKA22299.1 | TIGRFAM: TIGR00093: pseudouridine synthase; Pfam: RNA pseudouridylate synthase; Belongs to the pseudouridine synthase RsuA family. (188 aa) |
| | miaB | (dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (458 aa) |
| | ybeY | rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (164 aa) |
| | leuS | Pfam: tRNA synthetases class I (I, L, M and V); Pfam: Leucyl-tRNA synthetase, Domain 2; PRINTS: Leucyl-tRNA synthetase signature; Pfam: Anticodon-binding domain of tRNA; TIGRFAM: leuS_bact: leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (868 aa) |
| | rlmH | 50S rRNA methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (155 aa) |
| | AKA22219.1 | Pfam: LysR substrate binding domain; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Belongs to the LysR transcriptional regulatory family. (295 aa) |
| | nusB | Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (166 aa) |
| | rpoA | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (333 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (381 aa) |
| | AKA22123.1 | PRINTS: CRP bacterial regulatory protein HTH signature; Pfam: Bacterial regulatory proteins, crp family; SMART: Cyclic nucleotide-monophosphate binding domain; SMART: helix_turn_helix, cAMP Regulatory protein; Pfam: Cyclic nucleotide-binding domain. (214 aa) |
| | rsmA | 16S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (272 aa) |
| | cca | tRNA nucleotidyl transferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (409 aa) |
| | tsaD | UGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (341 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (654 aa) |
| | rpoD | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (615 aa) |
| | AKA22080.1 | Hypothetical protein; Pfam: Toprim domain. (886 aa) |
| | AKA22014.1 | Glycine cleavage system protein R; Pfam: ACT domain. (172 aa) |
| | AKA22008.1 | RNA polymerase sigma factor; Pfam: Sigma-70, region 4; Pfam: Sigma-70 region 2; TIGRFAM: sigma70-ECF: RNA polymerase sigma factor, sigma-70 family. (158 aa) |
| | AKA21988.1 | TIGRFAM: soxB: sarcosine oxidase, beta subunit family; Pfam: FAD dependent oxidoreductase. (416 aa) |
| | AKA21968.1 | Cytotoxic translational repressor of toxin-antitoxin stability system; Pfam: Plasmid stabilisation system protein. (84 aa) |
| | AKA21895.1 | RNA helicase; SMART: DEAD-like helicases superfamily; Pfam: DbpA RNA binding domain; Pfam: DEAD/DEAH box helicase; Pfam: Helicase conserved C-terminal domain; SMART: helicase superfamily c-terminal domain; Belongs to the DEAD box helicase family. (461 aa) |
| | AKA21860.1 | 16S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (239 aa) |
| | ruvX | Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (145 aa) |
| | kptA | RNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (182 aa) |
| | trmB | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (241 aa) |
| | rpoH | RNA polymerase sigma 70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (284 aa) |
| | AKA21805.1 | 16S rRNA methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. (206 aa) |
| | AKA21795.1 | Ferredoxin; Pfam: 4Fe-4S dicluster domain. (83 aa) |
| | rppH | RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (159 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa) |
| | AKA21664.1 | Nucleoside diphosphate kinase regulator; Pfam: Transcription elongation factor, GreA/GreB, C-term; Pfam: Rnk N-terminus. (137 aa) |
| | AKA21646.1 | methionyl-tRNA formyltransferase; Pfam: Formyl transferase. (242 aa) |
| | AKA21627.1 | Pfam: LysR substrate binding domain; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; PRINTS: LysR bacterial regulatory protein HTH signature; Belongs to the LysR transcriptional regulatory family. (306 aa) |
| | rph | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (240 aa) |
| | AKA21595.1 | Hypothetical protein; TIGRFAM: TIGR00255: TIGR00255 family protein; Pfam: YicC-like family, N-terminal region; Pfam: Domain of unknown function (DUF1732). (287 aa) |
| | rpoZ | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (87 aa) |
| | AKA21583.1 | HDOD domain-containing protein; Pfam: HDOD domain; Pfam: Aminoacyl-tRNA editing domain. (466 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (632 aa) |
| | AKA21459.1 | Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (300 aa) |
