STRINGSTRING
slyA slyA APG49711.1 APG49711.1 soxS_3 soxS_3 dpiA dpiA yvdT yvdT glcR_1 glcR_1 putA putA tetD_1 tetD_1 APG50957.1 APG50957.1 cynR_1 cynR_1 rpoS rpoS fecI_1 fecI_1 hcaR_1 hcaR_1 dmlR_1 dmlR_1 APG51118.1 APG51118.1 mgrA mgrA feaR feaR oxyR_2-2 oxyR_2-2 BGK56_09595 BGK56_09595 gltR_1 gltR_1 nhaR nhaR rob_2 rob_2 trpR trpR fecI_2 fecI_2 dmlR_6 dmlR_6 cynR_2 cynR_2 aarP aarP deoR deoR nifA nifA APG51463.1 APG51463.1 adiY adiY zur zur murR_3 murR_3 crp_1-2 crp_1-2 glpR_2 glpR_2 gltR gltR abgR_2 abgR_2 yqjI_2 yqjI_2 ampR ampR glpR_2-2 glpR_2-2 allS_1-2 allS_1-2 lutR_2 lutR_2 invF invF murR_2 murR_2 dmlR_5 dmlR_5 pdhR_2 pdhR_2 APG51903.1 APG51903.1 modE_2 modE_2 yegW yegW metJ metJ oxyR_3 oxyR_3 fabR fabR cynR_2-2 cynR_2-2 hcaR_2 hcaR_2 nsrR nsrR argR argR nusA nusA hmrR hmrR tetD_2 tetD_2 merR1 merR1 lutR_1 lutR_1 benM_2 benM_2 soxS_4 soxS_4 mcbR mcbR rpoH rpoH yvoA_3 yvoA_3 APG52436.1 APG52436.1 licR licR allS_4 allS_4 dmlR_4 dmlR_4 APG52532.1 APG52532.1 APG52533.1 APG52533.1 rpoD rpoD gcvA_2 gcvA_2 chbR chbR APG52737.1 APG52737.1 ripA_3-2 ripA_3-2 modE_1 modE_1 APG52897.1 APG52897.1 ripA_2 ripA_2 fur fur catM catM oxyR_2 oxyR_2 cueR_2-2 cueR_2-2 arsR arsR rob_1 rob_1 murR_1 murR_1 bigR bigR allS_1 allS_1 leuO leuO mraZ mraZ pdhR_1 pdhR_1 iciA iciA rhaS rhaS rpoE rpoE rseC rseC iscR iscR APG50549.1 APG50549.1 yvoA_1 yvoA_1 ripA_3 ripA_3 gltC_2-2 gltC_2-2 ydfH ydfH cysL cysL soxS_1 soxS_1 yvoA_2 yvoA_2 fadR fadR abgR_1 abgR_1 hnr hnr cysB cysB benM_1 benM_1 marR marR yjiR yjiR crp_1 crp_1 ada ada dmlR_2-2 dmlR_2-2 APG49937.1 APG49937.1 gcvA_1 gcvA_1 rhaR rhaR dmlR_2 dmlR_2 cueR_2 cueR_2 gabR gabR yqjI_1 yqjI_1 fnr fnr ybbH_1 ybbH_1 allS_2 allS_2 soxS_2 soxS_2 gltC_2 gltC_2 ydcR ydcR allS_3 allS_3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
slyATranscriptional regulator SlyA; Transcription regulator that can both activate or repress expression; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
APG49711.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
soxS_3AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
dpiATwo-component response regulator DpiA; Regulates the expression of citrate fermentation genes; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
yvdTTranscriptional regulator BetI; Repressor involved in choline regulation of the bet genes. (198 aa)
glcR_1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
putADelta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. (1327 aa)
tetD_1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
APG50957.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
cynR_1LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (301 aa)
rpoSRNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. (328 aa)
fecI_1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (176 aa)
hcaR_1LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (311 aa)
dmlR_1LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (306 aa)
APG51118.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (78 aa)
mgrAHomoprotocatechuate degradation operon regulator, HpaR; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
feaR4-hydroxyphenylacetate catabolism regulatory protein HpaA; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
oxyR_2-2Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (227 aa)
BGK56_09595Amino acid ABC transporter substrate-binding protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
gltR_1LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (283 aa)
nhaRTranscriptional activator NhaR; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (307 aa)
rob_2Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
trpRTrp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. (106 aa)
fecI_2RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (178 aa)
dmlR_6LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (307 aa)
cynR_2Homocysteine-binding; positive regulator of metA, metE and metH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (318 aa)
aarPTranscriptional regulator; Transcriptional activator of 2'-N-acetyltransferase. (135 aa)
deoRDeoR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
nifATranscriptional regulator; Sigma 54-dependent; regulates genes involved in forming a 2',3'-cyclic phosphodiester on RNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (526 aa)
APG51463.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
adiYHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
zurTranscriptional repressor; Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. (171 aa)
murR_3XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
crp_1-2Transcriptional regulator Crp; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
glpR_2DeoR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
gltRLysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (283 aa)
abgR_2LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (306 aa)
yqjI_2PadR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
ampRLysR family transcriptional regulator; This protein is a positive regulator of gene expression of beta-lactamase (AmpC); Belongs to the LysR transcriptional regulatory family. (292 aa)
glpR_2-2Transcriptional regulator; Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
allS_1-2LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (310 aa)
lutR_2GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
invFAraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
murR_2Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
dmlR_5LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (303 aa)
pdhR_2GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
APG51903.1MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
modE_2Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
yegWGntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
metJTranscriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. (105 aa)
oxyR_3DNA-binding transcriptional regulator OxyR; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (302 aa)
fabRDNA-binding transcriptional regulator FabR; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. (218 aa)
cynR_2-2Transposase; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon. (281 aa)
hcaR_2Transcriptional regulator IlvY; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (298 aa)
nsrRTranscriptional repressor NsrR; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. (140 aa)
argRArginine repressor; Regulates arginine biosynthesis genes. (156 aa)
nusATranscription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. (502 aa)
hmrRCu(I)-responsive transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
tetD_2Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa)
merR1MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
lutR_1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
benM_2Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (301 aa)
soxS_4Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
mcbRGntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
rpoHRNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (292 aa)
yvoA_3Histidine utilization repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
APG52436.1RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (481 aa)
licRTranscription antiterminator BglG; Derived by automated computational analysis using gene prediction method: Protein Homology. (653 aa)
allS_4LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (298 aa)
dmlR_4LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (297 aa)
APG52532.1DNA-binding transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
APG52533.1Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
rpoDRNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (617 aa)
gcvA_2Transcriptional regulator GcvA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (313 aa)
chbRTranscriptional regulator ChbR; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
APG52737.1DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
ripA_3-2AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
modE_1Molybdenum-dependent transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
APG52897.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
ripA_2AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
furFerric iron uptake transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. (149 aa)
catMLysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (301 aa)
oxyR_2LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (304 aa)
cueR_2-2Cu(I)-responsive transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa)
arsRTranscriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)
rob_1Right origin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
murR_1Fe-S cluster assembly protein HesB; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
bigRTranscriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)
allS_1LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (304 aa)
leuOTranscriptional regulator LeuO; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (317 aa)
mraZCell division/cell wall cluster transcriptional repressor MraZ; Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster. (152 aa)
pdhR_1Transcriptional regulator PdhR; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
iciATranscriptional regulator ArgP; Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. (300 aa)
rhaSAraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)
rpoERNA polymerase sigma factor RpoE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
rseCSoxR reducing system protein RseC; Involved in the reduction of the SoxR iron-sulfur cluster; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
iscRFe-S cluster assembly transcriptional regulator IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. (165 aa)
APG50549.1MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
yvoA_1Histidine utilization repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
ripA_3AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
gltC_2-2Transcriptional regulator LrhA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (309 aa)
ydfHGntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
cysLLysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (287 aa)
soxS_1AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
yvoA_2HipA protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
fadRFatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism. (238 aa)
abgR_1LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (291 aa)
hnrResponse regulator of RpoS; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. (332 aa)
cysBTranscriptional regulator CysB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (324 aa)
benM_1LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (300 aa)
marRTranscriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
yjiRGntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
crp_1Cyclic AMP receptor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
ada6-O-methylguanine DNA methyltransferase; Regulates genes involved in the repair of alkylated DNA; repairs DNA containing 6-O-methylguanine; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
dmlR_2-2LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (317 aa)
APG49937.1AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
gcvA_1LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (294 aa)
rhaRAraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
dmlR_2LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (300 aa)
cueR_2Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
gabRGntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (493 aa)
yqjI_1PadR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa)
fnrTranscriptional regulator; Global transcription factor that controls the expression of over 100 target genes in response to anoxia; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
ybbH_1Transcriptional regulator HexR; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
allS_2LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (287 aa)
soxS_2AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
gltC_2LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (295 aa)
ydcRGntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
allS_3LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (301 aa)
Your Current Organism:
Providencia stuartii
NCBI taxonomy Id: 588
Other names: ATCC 29914, CCUG 14805, CDC 2896-68, CIP 104687, DSM 4539, LMG 3260, LMG:3260, NCTC 11800, P. stuartii, Proteus stuartii
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.