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nuoF nuoF nuoJ nuoJ nuoL nuoL nuoM nuoM nuoN nuoN ssuA ssuA apxIB_1 apxIB_1 potA_1 potA_1 potH potH ydcV_1 ydcV_1 znuC znuC rbsA_1 rbsA_1 btuD btuD fliI fliI mgtB mgtB rbsA_2 rbsA_2 msbA msbA apxIB_2 apxIB_2 apxIB_3 apxIB_3 aarD aarD APG52964.1 APG52964.1 artP-2 artP-2 cysA_2 cysA_2 kdpA kdpA kdpB kdpB kdpC kdpC artP artP metN_2-2 metN_2-2 thiQ thiQ zntA zntA ydcV_2 ydcV_2 potB potB potA_2 potA_2 actP_1 actP_1 secG secG btuB btuB APG52000.1 APG52000.1 APG51998.1 APG51998.1 atpD atpD atpA atpA rbsA_3 rbsA_3 irtB irtB APG51842.1 APG51842.1 spaL spaL pstB pstB potA_3 potA_3 APG51385.1 APG51385.1 yddA yddA secD secD secF secF cyoD cyoD cyoC cyoC cyoB cyoB cyoA cyoA yheI yheI mdlB mdlB ccmA ccmA APG51108.1 APG51108.1 APG51107.1 APG51107.1 ndvA ndvA copA copA secA secA cysW_1 cysW_1 cysW_2 cysW_2 cysA_1 cysA_1 metN_2 metN_2 ndhC ndhC nuoB nuoB nuoC nuoC nuoG nuoG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nuoFNADH-quinone oxidoreductase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (452 aa)
nuoJNADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (181 aa)
nuoLNADH-quinone oxidoreductase subunit L; Derived by automated computational analysis using gene prediction method: Protein Homology. (618 aa)
nuoMNADH-quinone oxidoreductase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
nuoNNADH-quinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (487 aa)
ssuAABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
apxIB_1Colicin V synthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (726 aa)
potA_1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (360 aa)
potHSpermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
ydcV_1Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
znuCZinc ABC transporter ATP-binding protein ZnuC; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (255 aa)
rbsA_1D-xylose ABC transporter ATP-binding protein; With RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
btuDCobalamin ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
fliIFlagellar protein export ATPase FliI; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
mgtBMagnesium-translocating P-type ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (903 aa)
rbsA_2D-xylose ABC transporter ATP-binding protein; With RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
msbALipid ABC transporter permease/ATP-binding protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (581 aa)
apxIB_2Peptidase C39; Derived by automated computational analysis using gene prediction method: Protein Homology. (696 aa)
apxIB_3Peptidase C39; Derived by automated computational analysis using gene prediction method: Protein Homology. (702 aa)
aarDCysteine/glutathione ABC transporter permease/ATP-binding protein CydD; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity); Belongs to the ABC transporter superfamily. (588 aa)
APG52964.1In Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; Derived by automated computational analysis using gene prediction method: Protein Homology. (580 aa)
artP-2Arginine ABC transporter ATP-binding protein ArtP; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
cysA_2Molybdenum ABC transporter ATP-binding protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (357 aa)
kdpAPotassium-transporting ATPase subunit KdpA; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (567 aa)
kdpBPotassium-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (687 aa)
kdpCPotassium-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (197 aa)
artPArginine transporter ATP-binding subunit; With ArtMQJI transports arginine across the inner membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
metN_2-2D-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa)
thiQThiamine ABC transporter ATP-binding protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (235 aa)
zntAZinc/cadmium/mercury/lead-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (799 aa)
ydcV_2Spermidine/putrescine ABC transporter permease PotC; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
potBSpermidine/putrescine ABC transporter permease PotB; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
potA_2Putrescine/spermidine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (369 aa)
actP_1Copper-translocating P-type ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (832 aa)
secGPreprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (112 aa)
btuBTonB-dependent vitamin B12 receptor; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (628 aa)
APG52000.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
APG51998.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (460 aa)
atpAF0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (513 aa)
rbsA_3Ribose ABC transporter ATP-binding protein RbsA; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (504 aa)
irtBABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
APG51842.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa)
spaLEscN/YscN/HrcN family type III secretion system ATPase; Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells; probable catalytic subunit of a protein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
pstBPhosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (258 aa)
potA_3ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (338 aa)
APG51385.1Cytoplasmic protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
yddAHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (568 aa)
secDProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (604 aa)
secFProtein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (322 aa)
cyoDCytochrome o ubiquinol oxidase subunit IV; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
cyoCCytochrome o ubiquinol oxidase subunit III; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
cyoBCytochrome o ubiquinol oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heme-copper respiratory oxidase family. (663 aa)
cyoACytochrome o ubiquinol oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
yheIMultidrug ABC transporter permease/ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (581 aa)
mdlBMultidrug ABC transporter permease/ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (594 aa)
ccmAHeme ABC transporter ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (205 aa)
APG51108.1Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (575 aa)
APG51107.1Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa)
ndvAABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
copACu+ exporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (981 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (903 aa)
cysW_1Sulfate/thiosulfate transporter subunit; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (276 aa)
cysW_2Sulfate ABC transporter permease subunit CysW; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
cysA_1Sulfate/thiosulfate transporter subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (362 aa)
metN_2Methionine ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (337 aa)
ndhCNADH-quinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (147 aa)
nuoBNADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (224 aa)
nuoCNADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. (598 aa)
nuoGNADH-quinone oxidoreductase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (910 aa)
Your Current Organism:
Providencia stuartii
NCBI taxonomy Id: 588
Other names: ATCC 29914, CCUG 14805, CDC 2896-68, CIP 104687, DSM 4539, LMG 3260, LMG:3260, NCTC 11800, P. stuartii, Proteus stuartii
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