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ahpC ahpC fdhF fdhF andAb andAb thcD thcD nrdB nrdB nrdA nrdA dmsC_1 dmsC_1 dmsB_1 dmsB_1 ndh ndh ssuE ssuE ssuD ssuD guaB guaB glpB glpB fdnI fdnI fdnH fdnH APG53072.1 APG53072.1 APG53071.1 APG53071.1 APG52912.1 APG52912.1 dmsB_2 dmsB_2 sucB sucB sucA sucA sdhC sdhC nrdE nrdE nrdF2 nrdF2 BGK56_17190 BGK56_17190 gltB gltB gltD gltD glpA glpA dmsC_2 dmsC_2 dmsB_3 dmsB_3 odh odh gpsA gpsA fdoI fdoI fdoH_2 fdoH_2 APG51917.1 APG51917.1 ahpF ahpF APG51916.1 APG51916.1 APG51880.1 APG51880.1 hmp_2 hmp_2 paaC paaC APG51696.1 APG51696.1 paaA paaA glpD glpD narG narG narH narH narI narI tsaA tsaA cyoD cyoD cyoC cyoC efeO efeO efeU efeU tpd tpd folK folK APG50799.1 APG50799.1 hcr hcr aceE aceE aceF aceF lpdA lpdA gcvT gcvT gcvH gcvH gcvP gcvP yfhL yfhL ndhC ndhC nuoC nuoC nuoE nuoE nuoF nuoF nuoG nuoG nuoJ nuoJ nuoL nuoL nuoM nuoM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ahpCPeroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
fdhFCbbBc protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (762 aa)
andAbNaphthalene 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa)
thcDPyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
nrdBRibonucleotide-diphosphate reductase subunit beta; B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
nrdARibonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (763 aa)
dmsC_1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
dmsB_1Dimethyl sulfoxide reductase subunit A; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
ndhNADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
ssuEFMN reductase (NADPH); Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
ssuDAlkanesulfonate monooxygenase, FMNH(2)-dependent; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family. (382 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (488 aa)
glpBAnaerobic glycerol-3-phosphate dehydrogenase subunit B; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor. (431 aa)
fdnIFormate dehydrogenase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
fdnHFormate dehydrogenase subunit beta; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (293 aa)
APG53072.1Formate dehydrogenase-N subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (803 aa)
APG53071.1Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
APG52912.1Reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
dmsB_2Dimethylsulfoxide reductase, chain B; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
sucBDihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (404 aa)
sucA2-oxoglutarate dehydrogenase E1 component; Derived by automated computational analysis using gene prediction method: Protein Homology. (935 aa)
sdhCSuccinate dehydrogenase cytochrome b556 large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
nrdERibonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (693 aa)
nrdF2Class 1b ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (323 aa)
BGK56_17190Type IV secretion protein Rhs; Frameshifted; incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
gltBGlutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (1487 aa)
gltDGlutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
glpASn-glycerol-3-phosphate dehydrogenase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (551 aa)
dmsC_2Dimethylsulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
dmsB_3Dimethylsulfoxide reductase, chain B; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
odhHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (358 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (342 aa)
fdoIFormate dehydrogenase cytochrome b556 subunit; Cytochrome b556(FDO) component; heme containing; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
fdoH_2Formate dehydrogenase subunit beta; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (314 aa)
APG51917.1Formate dehydrogenase-N subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (803 aa)
ahpFAlkyl hydroperoxide reductase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (524 aa)
APG51916.1Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
APG51880.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
hmp_2Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
paaCphenylacetate-CoA oxygenase subunit PaaI; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
APG51696.11,2-phenylacetyl-CoA epoxidase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
paaA1,2-phenylacetyl-CoA epoxidase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
glpDGlycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (502 aa)
narGNitrate reductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1253 aa)
narHNitrate reductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
narIRespiratory nitrate reductase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
tsaAPeroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
cyoDCytochrome o ubiquinol oxidase subunit IV; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
cyoCCytochrome o ubiquinol oxidase subunit III; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
efeOHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
efeUHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
tpdHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
APG50799.1Ferredoxin-type protein NapG; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
hcrNADH oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
aceEPyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (888 aa)
aceFPyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (623 aa)
lpdADihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (364 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (130 aa)
gcvPGlycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (958 aa)
yfhLFerredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
ndhCNADH-quinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (147 aa)
nuoCNADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. (598 aa)
nuoENADH-quinone oxidoreductase subunit E; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
nuoFNADH-quinone oxidoreductase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (452 aa)
nuoGNADH-quinone oxidoreductase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (910 aa)
nuoJNADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (181 aa)
nuoLNADH-quinone oxidoreductase subunit L; Derived by automated computational analysis using gene prediction method: Protein Homology. (618 aa)
nuoMNADH-quinone oxidoreductase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
Your Current Organism:
Providencia stuartii
NCBI taxonomy Id: 588
Other names: ATCC 29914, CCUG 14805, CDC 2896-68, CIP 104687, DSM 4539, LMG 3260, LMG:3260, NCTC 11800, P. stuartii, Proteus stuartii
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