Your Input: | |
| | eda_1 | RNA polymerase sigma factor FliA; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa) |
| | ydjH_1 | Ketodeoxygluconokinase; Catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate-6-phosphate from 2-dehydro-3-deoxy-D-gluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa) |
| | glpX | Fructose-bisphosphatase, class II; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa) |
| | ppsA_1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa) |
| | pykF | Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (470 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (312 aa) |
| | pykA | Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (480 aa) |
| | zwf_1 | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa) |
| | accA_1 | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | frmA | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (370 aa) |
| | APG49929.1 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (276 aa) |
| | fumC_2 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa) |
| | acnA | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (890 aa) |
| | gapA | Type I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa) |
| | sdaA | L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa) |
| | maeB | Iron-regulated protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (759 aa) |
| | fbaB | Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa) |
| | icd | NADP-dependent isocitrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa) |
| | fumC_1 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (483 aa) |
| | accC_1 | acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (579 aa) |
| | katA | Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family. (479 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa) |
| | pta | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (714 aa) |
| | accD | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (327 aa) |
| | fadJ | Multifunctional fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. Belongs to the enoyl-CoA hydratase/isomerase family. In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (729 aa) |
| | cysK | Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (317 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa) |
| | gcvP | Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (958 aa) |
| | gcvH | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (130 aa) |
| | gcvT | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (364 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (416 aa) |
| | rpiA | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (218 aa) |
| | acnB | Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family. (865 aa) |
| | lpdA | Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa) |
| | aceF | Pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (623 aa) |
| | aceE | Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (888 aa) |
| | mmsA | Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa) |
| | folD | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (433 aa) |
| | APG50951.1 | 6-phosphogluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa) |
| | fbaA | Class II fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa) |
| | pgk | Phosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (387 aa) |
| | tktA | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (664 aa) |
| | talB | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (317 aa) |
| | cobC | Phosphoglycerate mutase; Catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (215 aa) |
| | serB | Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa) |
| | metF_2 | 5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (265 aa) |
| | fadB | Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (730 aa) |
| | gntK | Gluconate kinase; Thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa) |
| | pgi | Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (548 aa) |
| | ilvD_2 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (616 aa) |
| | eda_2 | Keto-deoxy-phosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa) |
| | aceA | Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa) |
| | aceB | Malate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (532 aa) |
| | cfxP | Phosphoribulokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa) |
| | paaH | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (512 aa) |
| | zwf_2 | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (480 aa) |
| | gnd_2 | 6-phosphogluconate dehydrogenase (decarboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa) |
| | APG51749.1 | Phosphoheptose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa) |
| | arcC2 | Carbamate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbamate kinase family. (316 aa) |
| | lsrF | Phospho-2-dehydro-3-deoxyheptonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa) |
| | hprA | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (331 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (539 aa) |
| | rpe_2 | Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (224 aa) |
| | acs | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates [...] (651 aa) |
| | APG51916.1 | Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa) |
| | APG51917.1 | Formate dehydrogenase-N subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (803 aa) |
| | fdoH_2 | Formate dehydrogenase subunit beta; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (314 aa) |
| | fdoI | Formate dehydrogenase cytochrome b556 subunit; Cytochrome b556(FDO) component; heme containing; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa) |
| | cysE_3 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (256 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (879 aa) |
| | metF_2-2 | Methylenetetrahydrofolate reductase [NAD(P)H]; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (294 aa) |
| | ilvA | PLP-dependent threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (522 aa) |
| | mqo | Malate:quinone oxidoreductase; Malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa) |
| | fbp | Fructose-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. (335 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa) |
| | fumB | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa) |
| | frdD | Fumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (117 aa) |
| | frdC | Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa) |
| | frdB | Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa) |
| | accC_2 | Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa) |
| | accB | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (158 aa) |
| | accA_2 | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | gltA | Citrate (Si)-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (428 aa) |
| | sdhC | Succinate dehydrogenase cytochrome b556 large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa) |
| | sdhD_2 | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (114 aa) |
| | sdhA_2 | Succinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa) |
| | sdhB_3 | Succinate dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa) |
| | sucA | 2-oxoglutarate dehydrogenase E1 component; Derived by automated computational analysis using gene prediction method: Protein Homology. (935 aa) |
| | sucB | Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (404 aa) |
| | sucC | succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa) |
| | sucD | succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa) |
| | gpmA | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa) |
| | pgl | 6-phosphogluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa) |
| | maeA | Malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; Derived by automated computational analysis using gene prediction method: Protein Homology. (565 aa) |
| | gnd_2-2 | Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa) |
| | sdaB | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (456 aa) |
| | serC | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (362 aa) |
