STRINGSTRING
bioB bioB Cpap_2512 Cpap_2512 Cpap_2534 Cpap_2534 Cpap_2535 Cpap_2535 Cpap_2536 Cpap_2536 Cpap_2887 Cpap_2887 thiC thiC thiM thiM thiE thiE Cpap_3859 Cpap_3859 Cpap_3860 Cpap_3860 Cpap_3861 Cpap_3861 Cpap_3862 Cpap_3862 Cpap_3863 Cpap_3863
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (323 aa)
Cpap_2512Radical SAM domain protein; KEGG: cce:Ccel_3189 biotin synthase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; biotin and thiamin synthesis associated. (345 aa)
Cpap_2534KEGG: cce:Ccel_3105 hypothetical protein. (81 aa)
Cpap_2535KEGG: cce:Ccel_3104 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SMART: biotin and thiamin synthesis associated; Elongator protein 3/MiaB/NifB. (470 aa)
Cpap_2536KEGG: cce:Ccel_3103 small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related. (396 aa)
Cpap_2887KEGG: cce:Ccel_1992 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. (270 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (436 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (273 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (210 aa)
Cpap_3859PFAM: thiamine monophosphate synthase; KEGG: ctc:CTC01746 regulatory protein TenI. (227 aa)
Cpap_3860TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; KEGG: cbe:Cbei_1520 thiamine biosynthesis protein ThiH; SMART: biotin and thiamin synthesis associated. (382 aa)
Cpap_3861Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (255 aa)
Cpap_3862KEGG: amt:Amet_4236 thiamine biosynthesis protein ThiF; TIGRFAM: thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein. (267 aa)
Cpap_3863KEGG: cbe:Cbei_1518 thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. (64 aa)
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
Server load: low (14%) [HD]