STRINGSTRING
Cpap_3912 Cpap_3912 mnmA mnmA scpB scpB Cpap_3222 Cpap_3222 thiI thiI Cpap_3726 Cpap_3726 Cpap_3862 Cpap_3862 Cpap_0191 Cpap_0191 Cpap_0491 Cpap_0491 Cpap_1243 Cpap_1243 prfA prfA Cpap_1994 Cpap_1994 Cpap_2904 Cpap_2904 Cpap_2927 Cpap_2927 Cpap_2968 Cpap_2968 iscS iscS Cpap_2970 Cpap_2970 Cpap_3863 Cpap_3863
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cpap_3912KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA-like domain-containing protein; DsrE family protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; Belongs to the sulfur carrier protein TusA family. (816 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (359 aa)
scpBChromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (190 aa)
Cpap_3222PFAM: aminotransferase class V; KEGG: cce:Ccel_1684 aminotransferase class V. (387 aa)
thiIThiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (391 aa)
Cpap_3726PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: sti:Sthe_0801 UBA/ThiF-type NAD/FAD binding protein. (339 aa)
Cpap_3862KEGG: amt:Amet_4236 thiamine biosynthesis protein ThiF; TIGRFAM: thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein. (267 aa)
Cpap_0191Cysteine desulfurase; Manually curated; KEGG: clj:CLJU_c14540 cysteine desulfurase; PFAM: aminotransferase class V. (396 aa)
Cpap_0491PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: cce:Ccel_0550 UBA/ThiF-type NAD/FAD binding protein. (258 aa)
Cpap_1243KEGG: cce:Ccel_0924 transcriptional regulator, BadM/Rrf2 family; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074. (148 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (359 aa)
Cpap_1994KEGG: cce:Ccel_0322 NifU-like domain-containing protein. (230 aa)
Cpap_2904Radical SAM domain protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (346 aa)
Cpap_2927PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: cce:Ccel_1964 fibronectin-binding A domain protein. (592 aa)
Cpap_2968KEGG: cce:Ccel_1933 transcriptional regulator, BadM/Rrf2 family; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074. (148 aa)
iscSCysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (393 aa)
Cpap_2970KEGG: cce:Ccel_1931 FeS cluster assembly scaffold protein NifU; TIGRFAM: FeS cluster assembly scaffold protein NifU; PFAM: nitrogen-fixing NifU domain protein. (153 aa)
Cpap_3863KEGG: cbe:Cbei_1518 thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. (64 aa)
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.