STRINGSTRING
SFK06298.1 SFK06298.1 SFI51757.1 SFI51757.1 SFI61448.1 SFI61448.1 SFI62886.1 SFI62886.1 SFI63855.1 SFI63855.1 SFI63893.1 SFI63893.1 SFI65120.1 SFI65120.1 SFI66470.1 SFI66470.1 SFI66506.1 SFI66506.1 pdhA-2 pdhA-2 fumC fumC SFI86112.1 SFI86112.1 SFJ05336.1 SFJ05336.1 SFJ19449.1 SFJ19449.1 SFJ19660.1 SFJ19660.1 SFJ34153.1 SFJ34153.1 SFJ34205.1 SFJ34205.1 SFJ34237.1 SFJ34237.1 SFJ34265.1 SFJ34265.1 mdh mdh sucC sucC sucD sucD SFJ34635.1 SFJ34635.1 SFJ34665.1 SFJ34665.1 SFJ34713.1 SFJ34713.1 SFJ43689.1 SFJ43689.1 SFJ93280.1 SFJ93280.1 SFJ96435.1 SFJ96435.1 SFJ97169.1 SFJ97169.1 pckA pckA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SFK06298.1Isocitrate dehydrogenase. (728 aa)
SFI51757.1Antitoxin CptB. (96 aa)
SFI61448.1Citrate synthase; Belongs to the citrate synthase family. (432 aa)
SFI62886.1Dihydrolipoamide dehydrogenase. (465 aa)
SFI63855.1Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (895 aa)
SFI63893.1Aconitase. (929 aa)
SFI65120.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (393 aa)
SFI66470.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (446 aa)
SFI66506.1Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (458 aa)
pdhA-2Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (341 aa)
fumCFumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
SFI86112.1Isocitrate dehydrogenase (NADP); Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa)
SFJ05336.1Pyruvate-ferredoxin/flavodoxin oxidoreductase. (1210 aa)
SFJ19449.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1147 aa)
SFJ19660.1Hypothetical protein. (646 aa)
SFJ34153.1Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (259 aa)
SFJ34205.1Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (602 aa)
SFJ34237.1Succinate dehydrogenase / fumarate reductase membrane anchor subunit. (123 aa)
SFJ34265.1Succinate dehydrogenase subunit C. (129 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
sucCsuccinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (397 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
SFJ34635.12-oxoglutarate dehydrogenase E1 component. (989 aa)
SFJ34665.12-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (500 aa)
SFJ34713.1Dihydrolipoamide dehydrogenase. (464 aa)
SFJ43689.1Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. (465 aa)
SFJ93280.1succinyl-CoA:acetate CoA-transferase. (504 aa)
SFJ96435.1Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (790 aa)
SFJ97169.1Dihydrolipoamide dehydrogenase. (467 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (532 aa)
Your Current Organism:
Celeribacter neptunius
NCBI taxonomy Id: 588602
Other names: C. neptunius, CIP 109922, Celeribacter neptunius Ivanova et al. 2010, DSM 26471, KMM 6012, alpha proteobacterium H 14, strain H 14
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