(11 nodes) AP-2 adaptor complex, and AP-1/2/4 complex subunit beta network (Paramecium tetraurelia)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0CCJ0_PARTE	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (143 aa)
	A0CS57_PARTE	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (431 aa)
	A0D0F0_PARTE	AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (657 aa)
	A0D1K9_PARTE	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (953 aa)
	A0D5K8_PARTE	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (147 aa)
	A0D5T2_PARTE	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (428 aa)
	A0DC58_PARTE	AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (662 aa)
	A0DEM5_PARTE	Uncharacterized protein. (550 aa)
	A0DI20_PARTE	Uncharacterized protein. (938 aa)
	A0ECL0_PARTE	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (431 aa)
	PTMB.214c	DUF1681 domain-containing protein. (280 aa)

Your Current Organism:

Paramecium tetraurelia

NCBI taxonomy Id: 5888
Other names: P. tetraurelia, Paramecium aurelia syngen 4

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0CCJ0_PARTE	A0CS57_PARTE	A0CCJ0	A0CS57	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.998
A0CCJ0_PARTE	A0D0F0_PARTE	A0CCJ0	A0D0F0	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.995
A0CCJ0_PARTE	A0D1K9_PARTE	A0CCJ0	A0D1K9	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.998
A0CCJ0_PARTE	A0D5K8_PARTE	A0CCJ0	A0D5K8	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.900
A0CCJ0_PARTE	A0D5T2_PARTE	A0CCJ0	A0D5T2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.998
A0CCJ0_PARTE	A0DC58_PARTE	A0CCJ0	A0DC58	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.995
A0CCJ0_PARTE	A0DEM5_PARTE	A0CCJ0	A0DEM5	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Uncharacterized protein.	0.998
A0CCJ0_PARTE	A0DI20_PARTE	A0CCJ0	A0DI20	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Uncharacterized protein.	0.995
A0CCJ0_PARTE	A0ECL0_PARTE	A0CCJ0	A0ECL0	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.998
A0CCJ0_PARTE	PTMB.214c	A0CCJ0	Q6BG09	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	DUF1681 domain-containing protein.	0.957
A0CS57_PARTE	A0CCJ0_PARTE	A0CS57	A0CCJ0	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.998
A0CS57_PARTE	A0D0F0_PARTE	A0CS57	A0D0F0	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.992
A0CS57_PARTE	A0D1K9_PARTE	A0CS57	A0D1K9	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.998
A0CS57_PARTE	A0D5K8_PARTE	A0CS57	A0D5K8	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.998
A0CS57_PARTE	A0D5T2_PARTE	A0CS57	A0D5T2	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.901
A0CS57_PARTE	A0DC58_PARTE	A0CS57	A0DC58	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.992
A0CS57_PARTE	A0DEM5_PARTE	A0CS57	A0DEM5	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Uncharacterized protein.	0.998
A0CS57_PARTE	A0DI20_PARTE	A0CS57	A0DI20	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Uncharacterized protein.	0.992
A0CS57_PARTE	A0ECL0_PARTE	A0CS57	A0ECL0	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.900
A0CS57_PARTE	PTMB.214c	A0CS57	Q6BG09	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	DUF1681 domain-containing protein.	0.983