(33 nodes) HDR through Single Strand Annealing (SSA), and Homologous DNA Pairing and Strand Exchange network (Paramecium tetraurelia)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0BC65_PARTE	Rep_fac-A_C domain-containing protein. (635 aa)
	A0BFX1_PARTE	HD domain-containing protein. (217 aa)
	A0BH35_PARTE	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (667 aa)
	A0BKF1_PARTE	Uncharacterized protein. (741 aa)
	A0BKS9_PARTE	Uncharacterized protein. (563 aa)
	A0BMB8_PARTE	Uncharacterized protein. (761 aa)
	A0BNB9_PARTE	Dna2 domain-containing protein. (896 aa)
	A0C1P3_PARTE	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (340 aa)
	A0C3W1_PARTE	Uncharacterized protein. (553 aa)
	A0C7G1_PARTE	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (889 aa)
	A0CBI3_PARTE	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (337 aa)
	A0CLD4_PARTE	SAS-6_N domain-containing protein. (591 aa)
	A0CUR5_PARTE	Uncharacterized protein. (731 aa)
	A0CV46_PARTE	AAA_23 domain-containing protein. (1237 aa)
	A0CXL6_PARTE	Uncharacterized protein. (633 aa)
	A0CYN4_PARTE	Uncharacterized protein. (632 aa)
	A0D0I8_PARTE	ANK_REP_REGION domain-containing protein. (851 aa)
	A0DCX6_PARTE	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (1445 aa)
	A0DEK9_PARTE	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (859 aa)
	A0DFA4_PARTE	RECA_2 domain-containing protein. (256 aa)
	A0DGW1_PARTE	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (949 aa)
	A0DIK3_PARTE	Protein kinase domain-containing protein. (294 aa)
	A0DM04_PARTE	Uncharacterized protein. (560 aa)
	A0DRL5_PARTE	Uncharacterized protein. (311 aa)
	A0DS57_PARTE	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (895 aa)
	A0DUM4_PARTE	Mre11_DNA_bind domain-containing protein. (1041 aa)
	A0DX38_PARTE	Uncharacterized protein. (971 aa)
	A0E2K1_PARTE	Uncharacterized protein. (741 aa)
	A0E597_PARTE	Mre11_DNA_bind domain-containing protein. (674 aa)
	A0E7B8_PARTE	Uncharacterized protein. (730 aa)
	A0E8C3_PARTE	SAS-6_N domain-containing protein. (466 aa)
	A0EDE1_PARTE	BRCA-2_OB1 domain-containing protein. (572 aa)
	A0EFE2_PARTE	Dna2 domain-containing protein. (859 aa)

Your Current Organism:

Paramecium tetraurelia

NCBI taxonomy Id: 5888
Other names: P. tetraurelia, Paramecium aurelia syngen 4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0BC65_PARTE	A0BFX1_PARTE	A0BC65	A0BFX1	Rep_fac-A_C domain-containing protein.	HD domain-containing protein.	0.935
A0BC65_PARTE	A0BH35_PARTE	A0BC65	A0BH35	Rep_fac-A_C domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.909
A0BC65_PARTE	A0BKF1_PARTE	A0BC65	A0BKF1	Rep_fac-A_C domain-containing protein.	Uncharacterized protein.	0.909
A0BC65_PARTE	A0BKS9_PARTE	A0BC65	A0BKS9	Rep_fac-A_C domain-containing protein.	Uncharacterized protein.	0.837
A0BC65_PARTE	A0BMB8_PARTE	A0BC65	A0BMB8	Rep_fac-A_C domain-containing protein.	Uncharacterized protein.	0.755
A0BC65_PARTE	A0BNB9_PARTE	A0BC65	A0BNB9	Rep_fac-A_C domain-containing protein.	Dna2 domain-containing protein.	0.971
A0BC65_PARTE	A0C1P3_PARTE	A0BC65	A0C1P3	Rep_fac-A_C domain-containing protein.	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.	0.975
A0BC65_PARTE	A0C3W1_PARTE	A0BC65	A0C3W1	Rep_fac-A_C domain-containing protein.	Uncharacterized protein.	0.829
A0BC65_PARTE	A0C7G1_PARTE	A0BC65	A0C7G1	Rep_fac-A_C domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.909
A0BC65_PARTE	A0CBI3_PARTE	A0BC65	A0CBI3	Rep_fac-A_C domain-containing protein.	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.	0.975
A0BC65_PARTE	A0CLD4_PARTE	A0BC65	A0CLD4	Rep_fac-A_C domain-containing protein.	SAS-6_N domain-containing protein.	0.966
A0BC65_PARTE	A0CUR5_PARTE	A0BC65	A0CUR5	Rep_fac-A_C domain-containing protein.	Uncharacterized protein.	0.661
A0BC65_PARTE	A0CV46_PARTE	A0BC65	A0CV46	Rep_fac-A_C domain-containing protein.	AAA_23 domain-containing protein.	0.882
A0BC65_PARTE	A0D0I8_PARTE	A0BC65	A0D0I8	Rep_fac-A_C domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.810
A0BC65_PARTE	A0DCX6_PARTE	A0BC65	A0DCX6	Rep_fac-A_C domain-containing protein.	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.980
A0BC65_PARTE	A0DEK9_PARTE	A0BC65	A0DEK9	Rep_fac-A_C domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.921
A0BC65_PARTE	A0DFA4_PARTE	A0BC65	A0DFA4	Rep_fac-A_C domain-containing protein.	RECA_2 domain-containing protein.	0.939
A0BC65_PARTE	A0DGW1_PARTE	A0BC65	A0DGW1	Rep_fac-A_C domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.856
A0BC65_PARTE	A0DIK3_PARTE	A0BC65	A0DIK3	Rep_fac-A_C domain-containing protein.	Protein kinase domain-containing protein.	0.752
A0BC65_PARTE	A0DM04_PARTE	A0BC65	A0DM04	Rep_fac-A_C domain-containing protein.	Uncharacterized protein.	0.829