STRINGSTRING
lpxC lpxC lpxD lpxD fabZ fabZ ANF53975.1 ANF53975.1 ANF53976.1 ANF53976.1 ANF53977.1 ANF53977.1 kdsA kdsA hldE hldE hldD hldD ANF54822.1 ANF54822.1 ANF54823.1 ANF54823.1 ANF54824.1 ANF54824.1 ANF54825.1 ANF54825.1 lpxK lpxK ANF54835.1 ANF54835.1 ANF54911.1 ANF54911.1 ANF55198.1 ANF55198.1 ANF55491.1 ANF55491.1 ANF55579.1 ANF55579.1 ANF55708.1 ANF55708.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (299 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (339 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (154 aa)
ANF53975.1acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (262 aa)
ANF53976.1UDP-2,3-diacylglucosamine pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
ANF53977.1lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (388 aa)
kdsA3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. (283 aa)
hldEBifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (486 aa)
hldDADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (333 aa)
ANF54822.1Protein tyrosine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
ANF54823.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (629 aa)
ANF54824.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
ANF54825.13-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (433 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (338 aa)
ANF54835.1Lipid A biosynthesis acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
ANF54911.1Heptosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
ANF55198.13-deoxy-manno-octulosonate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
ANF55491.1D,D-heptose 1,7-bisphosphate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
ANF55579.1Heptosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
ANF55708.1D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily. (331 aa)
Your Current Organism:
Brevundimonas naejangsanensis
NCBI taxonomy Id: 588932
Other names: B. naejangsanensis, Brevundimonas naejangsanensis Kang et al. 2009, CCUG 57609, DSM 23858, KCTC 22631, strain BIO-TAS2-2
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