(16 nodes) Mixed, incl. Vitamin B6 biosynthetic process, and LOG family network (Brevundimonas naejangsanensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANF53871.1	Pyridoxal kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyridoxine kinase family. (266 aa)
	pdxH	Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (218 aa)
	ANF54419.1	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
	era	GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (321 aa)
	ANF54422.1	Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (308 aa)
	acpS	holo-ACP synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (133 aa)
	pdxJ	Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (256 aa)
	ANF54426.1	Rossman fold protein, TIGR00730 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family. (259 aa)
	ANF54455.1	Hemolysin; Derived by automated computational analysis using gene prediction method: Protein Homology. (100 aa)
	ANF55909.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (62 aa)
	ANF55910.1	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
	pdxA	4-hydroxythreonine-4-phosphate dehydrogenase PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (339 aa)
	rsmA	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (270 aa)
	ANF54463.1	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
	ANF54464.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
	apaG	Co2+/Mg2+ efflux protein ApaG; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)

Your Current Organism:

Brevundimonas naejangsanensis

NCBI taxonomy Id: 588932
Other names: B. naejangsanensis, Brevundimonas naejangsanensis Kang et al. 2009, CCUG 57609, DSM 23858, KCTC 22631, strain BIO-TAS2-2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANF53871.1	pdxH	DA69_03365	DA69_04850	Pyridoxal kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyridoxine kinase family.	Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).	0.928
ANF53871.1	pdxJ	DA69_03365	DA69_06525	Pyridoxal kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyridoxine kinase family.	Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.	0.902
ANF54419.1	ANF54422.1	DA69_06500	DA69_06515	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.	0.773
ANF54419.1	ANF54426.1	DA69_06500	DA69_06535	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Rossman fold protein, TIGR00730 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family.	0.411
ANF54419.1	acpS	DA69_06500	DA69_06520	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	holo-ACP synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.	0.514
ANF54419.1	era	DA69_06500	DA69_06505	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	0.773
ANF54419.1	pdxJ	DA69_06500	DA69_06525	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.	0.512
ANF54422.1	ANF54419.1	DA69_06515	DA69_06500	Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
ANF54422.1	ANF54426.1	DA69_06515	DA69_06535	Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.	Rossman fold protein, TIGR00730 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family.	0.453
ANF54422.1	acpS	DA69_06515	DA69_06520	Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.	holo-ACP synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.	0.605
ANF54422.1	era	DA69_06515	DA69_06505	Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.	GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	0.850
ANF54422.1	pdxJ	DA69_06515	DA69_06525	Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.	Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.	0.605
ANF54426.1	ANF54419.1	DA69_06535	DA69_06500	Rossman fold protein, TIGR00730 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family.	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.411
ANF54426.1	ANF54422.1	DA69_06535	DA69_06515	Rossman fold protein, TIGR00730 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family.	Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.	0.453
ANF54426.1	acpS	DA69_06535	DA69_06520	Rossman fold protein, TIGR00730 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family.	holo-ACP synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.	0.611
ANF54426.1	era	DA69_06535	DA69_06505	Rossman fold protein, TIGR00730 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family.	GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	0.411
ANF54426.1	pdxJ	DA69_06535	DA69_06525	Rossman fold protein, TIGR00730 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family.	Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.	0.659
ANF54455.1	ANF55909.1	DA69_06710	DA69_06715	Hemolysin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.753
ANF54463.1	ANF54464.1	DA69_06760	DA69_06765	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.656
ANF54463.1	ANF55910.1	DA69_06760	DA69_06745	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.768