node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANF54465.1 | ANF54467.1 | DA69_06770 | DA69_06780 | tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | YicC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.782 |
ANF54465.1 | ANF55677.1 | DA69_06770 | DA69_13595 | tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.905 |
ANF54465.1 | gmk | DA69_06770 | DA69_06775 | tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.792 |
ANF54465.1 | guaA | DA69_06770 | DA69_02865 | tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.525 |
ANF54465.1 | mltG | DA69_06770 | DA69_06785 | tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. | 0.782 |
ANF54467.1 | ANF54465.1 | DA69_06780 | DA69_06770 | YicC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.782 |
ANF54467.1 | gmk | DA69_06780 | DA69_06775 | YicC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.923 |
ANF54467.1 | mltG | DA69_06780 | DA69_06785 | YicC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. | 0.820 |
ANF55340.1 | ANF55400.1 | DA69_11650 | DA69_12025 | Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.901 |
ANF55340.1 | ANF55677.1 | DA69_11650 | DA69_13595 | Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.906 |
ANF55340.1 | gmk | DA69_11650 | DA69_06775 | Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.902 |
ANF55340.1 | guaA | DA69_11650 | DA69_02865 | Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.932 |
ANF55340.1 | guaB | DA69_11650 | DA69_02845 | Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.914 |
ANF55340.1 | purA | DA69_11650 | DA69_01085 | Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.918 |
ANF55400.1 | ANF55340.1 | DA69_12025 | DA69_11650 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
ANF55400.1 | ANF55677.1 | DA69_12025 | DA69_13595 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.907 |
ANF55400.1 | guaA | DA69_12025 | DA69_02865 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.971 |
ANF55400.1 | guaB | DA69_12025 | DA69_02845 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.946 |
ANF55400.1 | purA | DA69_12025 | DA69_01085 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.548 |
ANF55677.1 | ANF54465.1 | DA69_13595 | DA69_06770 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.905 |