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Ferp_1249 Ferp_1249 Ferp_2530 Ferp_2530 Ferp_2510 Ferp_2510 Ferp_2467 Ferp_2467 Ferp_2440 Ferp_2440 Ferp_2329 Ferp_2329 atpE atpE atpC atpC atpF atpF atpA atpA atpB atpB atpD atpD purM purM Ferp_2227 Ferp_2227 hpt hpt pyrE pyrE prs prs coaD coaD Ferp_1982 Ferp_1982 Ferp_1945 Ferp_1945 Ferp_1890 Ferp_1890 purF purF Ferp_1826 Ferp_1826 Ferp_1825 Ferp_1825 purP purP Ferp_1659 Ferp_1659 mfnA mfnA Ferp_1579 Ferp_1579 Ferp_1566 Ferp_1566 Ferp_1528 Ferp_1528 Ferp_1511 Ferp_1511 purQ purQ purL purL purS purS Ferp_1355 Ferp_1355 adk adk Ferp_1101 Ferp_1101 Ferp_1086 Ferp_1086 Ferp_1034 Ferp_1034 Ferp_1028 Ferp_1028 purD purD Ferp_1003 Ferp_1003 Ferp_0943 Ferp_0943 Ferp_0934 Ferp_0934 ribK ribK Ferp_0893 Ferp_0893 Ferp_0892 Ferp_0892 guaAA guaAA Ferp_0788 Ferp_0788 ndk ndk purA purA pyrG pyrG guaAB guaAB pyrF pyrF purE purE purC purC carA carA carB carB Ferp_0316 Ferp_0316 Ferp_0142 Ferp_0142 Ferp_0141 Ferp_0141 pyrB pyrB Ferp_0060 Ferp_0060 pyrD pyrD
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Ferp_12492-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (292 aa)
Ferp_2530PFAM: phosphoribosyltransferase; KEGG: mma:MM_1262 xanthine-guanine phosphoribosyltransferase. (234 aa)
Ferp_2510KEGG: afu:AF0589 ribose-phosphate pyrophosphokinase (PrsA-1); TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family. (277 aa)
Ferp_2467PFAM: acyl-CoA dehydrogenase domain protein; KEGG: afu:AF0671 acyl-CoA dehydrogenase (acd-4). (415 aa)
Ferp_2440TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; KEGG: afu:AF2242 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (450 aa)
Ferp_2329PFAM: acyl-CoA dehydrogenase domain protein; KEGG: rpe:RPE_3222 butyryl-CoA dehydrogenase. (380 aa)
atpEH+transporting two-sector ATPase E subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (185 aa)
atpCATP synthase A1, C subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (346 aa)
atpFVacuolar H+transporting two-sector ATPase F subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (101 aa)
atpAATP synthase, A subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (573 aa)
atpBATP synthase, B subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (462 aa)
atpDV-type ATPase, D subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (210 aa)
purMTIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; KEGG: afu:AF1693 phosphoribosylaminoimidazole synthetase. (323 aa)
Ferp_2227Protein of unknown function DUF359; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (190 aa)
hptPhosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. (187 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (170 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (274 aa)
coaDCytidyltransferase-related domain protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. (148 aa)
Ferp_1982PFAM: DRTGG domain protein; KEGG: afu:AF1212 hypothetical protein. (343 aa)
Ferp_1945PFAM: acyl-CoA dehydrogenase domain protein; KEGG: afu:AF1141 acyl-CoA dehydrogenase (acd-8). (390 aa)
Ferp_1890PFAM: phosphoribosyltransferase; KEGG: afu:AF0386 orotate phosphoribosyltransferase-like protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (193 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (453 aa)
Ferp_1826TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: afu:AF2055 2-ketoisovalerate ferredoxin oxidoreductase, subunit gamma (VorG). (164 aa)
Ferp_1825TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mvn:Mevan_0815 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit. (83 aa)
purPIMP biosynthesis enzyme PurP domain protein; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (356 aa)
Ferp_1659PFAM: phosphoribulokinase/uridine kinase; KEGG: mtp:Mthe_1447 phosphoribulokinase/uridine kinase. (311 aa)
mfnAPyridoxal-dependent decarboxylase; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily. (363 aa)
Ferp_1579PFAM: acyl-CoA dehydrogenase domain protein; KEGG: afu:AF2057 acyl-CoA dehydrogenase (acd-10). (383 aa)
Ferp_1566PFAM: acyl-CoA dehydrogenase domain protein; KEGG: afu:AF1026 acyl-CoA dehydrogenase (acd-7). (395 aa)
Ferp_1528PFAM: Protein of unknown function DUF137; KEGG: iho:Igni_0452 hypothetical protein. (249 aa)
Ferp_1511PFAM: acyl-CoA dehydrogenase domain protein; KEGG: Hypothetical protein CBG15946; K00249 acyl-CoA dehydrogenase. (355 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (270 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (755 aa)
purSPhosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (80 aa)
Ferp_1355TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; KEGG: afu:AF2250 dihydroorotase. (401 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa)
Ferp_1101Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (219 aa)
Ferp_1086TIGRFAM: adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: afu:AF1988 hypothetical protein. (173 aa)
Ferp_1034TIGRFAM: indolepyruvate ferredoxin oxidoreductase, beta subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: afu:AF2030 indolepyruvate ferredoxin oxidoreductase, subunit beta (IorB). (195 aa)
Ferp_10282-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (310 aa)
purDKEGG: afu:AF1157 phosphoribosylamine--glycine ligase (PurD); TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family. (476 aa)
Ferp_1003PFAM: acyl-CoA dehydrogenase domain protein; KEGG: afu:AF1293 acyl-CoA dehydrogenase (acd-9). (381 aa)
Ferp_0943PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: afu:AF0528 cytochrome-c3 hydrogenase, subunit gamma. (233 aa)
Ferp_0934PFAM: IMP biosynthesis enzyme PurP domain protein; IMP biosynthesis enzyme PurP; KEGG: afu:AF0256 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase-like protein. (376 aa)
ribKTranscriptional regulator, MarR family; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (215 aa)
Ferp_0893TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: afu:AF1700 pyruvate ferredoxin oxidoreductase, subunit delta (PorD). (97 aa)
Ferp_0892TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: afu:AF1699 pyruvate ferredoxin oxidoreductase subunit gamma. (193 aa)
guaAAGMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP. (183 aa)
Ferp_0788PFAM: AMP-dependent synthetase and ligase; KEGG: chy:CHY_0659 acetyl-CoA synthetase. (634 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (151 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (337 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (531 aa)
guaABGMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (304 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (213 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (157 aa)
purCKEGG: afu:AF1272 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. (341 aa)
carATIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: afu:AF1273 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. (358 aa)
carBTIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; KEGG: afu:AF1274 carbamoyl-phosphate synthase, large (or ammonia) subunit (CarB); Belongs to the CarB family. (1081 aa)
Ferp_0316PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: afu:AF1275 hypothetical protein. (236 aa)
Ferp_0142KEGG: afu:AF1646 hypothetical protein. (265 aa)
Ferp_0141Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; KEGG: afu:AF1645 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein. (399 aa)
pyrBKEGG: afu:AF0106 aspartate carbamoyltransferase, catalytic subunit (PyrB); TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region. (298 aa)
Ferp_0060TIGRFAM: methanogenesis marker protein 2; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: mtp:Mthe_0762 AIR synthase-like protein. (311 aa)
pyrDDihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. (297 aa)
Your Current Organism:
Ferroglobus placidus
NCBI taxonomy Id: 589924
Other names: F. placidus DSM 10642, Ferroglobus placidus AEDII12DO, Ferroglobus placidus DSM 10642, Ferroglobus placidus str. DSM 10642, Ferroglobus placidus strain DSM 10642
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