STRINGSTRING
ilvE ilvE Ferp_0141 Ferp_0141 Ferp_0142 Ferp_0142 ilvC ilvC Ferp_1028 Ferp_1028 Ferp_1249 Ferp_1249 Ferp_1528 Ferp_1528 ilvD ilvD mfnA mfnA coaD coaD Ferp_2162 Ferp_2162 Ferp_2163 Ferp_2163 Ferp_2227 Ferp_2227
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (292 aa)
Ferp_0141Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; KEGG: afu:AF1645 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein. (399 aa)
Ferp_0142KEGG: afu:AF1646 hypothetical protein. (265 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (334 aa)
Ferp_10282-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (310 aa)
Ferp_12492-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (292 aa)
Ferp_1528PFAM: Protein of unknown function DUF137; KEGG: iho:Igni_0452 hypothetical protein. (249 aa)
ilvDKEGG: afu:AF1014 dihydroxy-acid dehydratase (IlvD); TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (546 aa)
mfnAPyridoxal-dependent decarboxylase; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily. (363 aa)
coaDCytidyltransferase-related domain protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. (148 aa)
Ferp_2162TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; KEGG: afu:AF1719 acetolactate synthase 3 regulatory subunit. (161 aa)
Ferp_2163TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; KEGG: afu:AF1720 acetolactate synthase 3 catalytic subunit. (554 aa)
Ferp_2227Protein of unknown function DUF359; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (190 aa)
Your Current Organism:
Ferroglobus placidus
NCBI taxonomy Id: 589924
Other names: F. placidus DSM 10642, Ferroglobus placidus AEDII12DO, Ferroglobus placidus DSM 10642, Ferroglobus placidus str. DSM 10642, Ferroglobus placidus strain DSM 10642
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