STRINGSTRING
ACZ75121.1 ACZ75121.1 ACZ75122.1 ACZ75122.1 ACZ75161.1 ACZ75161.1 ACZ75208.1 ACZ75208.1 ACZ75312.1 ACZ75312.1 ACZ75536.1 ACZ75536.1 ACZ75537.1 ACZ75537.1 ACZ75538.1 ACZ75538.1 ACZ75539.1 ACZ75539.1 ACZ75540.1 ACZ75540.1 ACZ75541.1 ACZ75541.1 ACZ75698.1 ACZ75698.1 ACZ75699.1 ACZ75699.1 ACZ75751.1 ACZ75751.1 ACZ75752.1 ACZ75752.1 ACZ75875.1 ACZ75875.1 ACZ75876.1 ACZ75876.1 rcsC rcsC rcsB rcsB rcsD rcsD ACZ76147.1 ACZ76147.1 ACZ76192.1 ACZ76192.1 ACZ76206.1 ACZ76206.1 ACZ76207.1 ACZ76207.1 ACZ76217.1 ACZ76217.1 ACZ76218.1 ACZ76218.1 ACZ76219.1 ACZ76219.1 ACZ76220.1 ACZ76220.1 ACZ76221.1 ACZ76221.1 ACZ76222.1 ACZ76222.1 ACZ76350.1 ACZ76350.1 ACZ76475.1 ACZ76475.1 ACZ76616.1 ACZ76616.1 ACZ76617.1 ACZ76617.1 ACZ76676.1 ACZ76676.1 ACZ76677.1 ACZ76677.1 ACZ76750.1 ACZ76750.1 ACZ76751.1 ACZ76751.1 ACZ76784.1 ACZ76784.1 ACZ76785.1 ACZ76785.1 ACZ76793.1 ACZ76793.1 rssB rssB ACZ77003.1 ACZ77003.1 ACZ77004.1 ACZ77004.1 ACZ77343.1 ACZ77343.1 ACZ77344.1 ACZ77344.1 ACZ77392.1 ACZ77392.1 ACZ77484.1 ACZ77484.1 ACZ77485.1 ACZ77485.1 ACZ77713.1 ACZ77713.1 ACZ77754.1 ACZ77754.1 ACZ77756.1 ACZ77756.1 ACZ77836.1 ACZ77836.1 mdtA mdtA mdtB mdtB mdtC mdtC mdtD mdtD ACZ77841.1 ACZ77841.1 ACZ77842.1 ACZ77842.1 ACZ77843.1 ACZ77843.1 ACZ77844.1 ACZ77844.1 ACZ77934.1 ACZ77934.1 ACZ77935.1 ACZ77935.1 ACZ78163.1 ACZ78163.1 ACZ78230.1 ACZ78230.1 ACZ78279.1 ACZ78279.1 ACZ78428.1 ACZ78428.1 ACZ78435.1 ACZ78435.1 ACZ78579.1 ACZ78579.1 ACZ78580.1 ACZ78580.1 ACZ78621.1 ACZ78621.1 ACZ78645.1 ACZ78645.1 ACZ78646.1 ACZ78646.1 ACZ78827.1 ACZ78827.1 ACZ78828.1 ACZ78828.1 ACZ79008.1 ACZ79008.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACZ75121.1KEGG: dda:Dd703_3722 two component heavy metal response transcriptional regulator, winged helix family; TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver. (223 aa)
ACZ75122.1Multi-sensor signal transduction histidine kinase; Member of a two-component regulatory system. (477 aa)
ACZ75161.1KEGG: dze:Dd1591_3836 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein. (648 aa)
ACZ75208.1KEGG: dze:Dd1591_3789 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. (779 aa)
ACZ75312.1KEGG: dze:Dd1591_1290 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein. (501 aa)
ACZ75536.1Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: cko:CKO_02245 hypothetical protein. (490 aa)
ACZ75537.1Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: kpe:KPK_3672 DNA-binding response regulator. (240 aa)
ACZ75538.1KEGG: eci:UTI89_C4930 hypothetical protein. (199 aa)
ACZ75539.1PFAM: oxidoreductase molybdopterin binding; KEGG: ecp:ECP_4560 hypothetical protein. (256 aa)
ACZ75540.1KEGG: bur:Bcep18194_A4332 hypothetical protein. (90 aa)
ACZ75541.1PFAM: helix-turn-helix HxlR type; KEGG: dze:Dd1591_3391 transcriptional regulator, HxlR family. (125 aa)
ACZ75698.1Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: dze:Dd1591_3275 two component transcriptional regulator, winged helix family. (226 aa)
ACZ75699.1Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: dze:Dd1591_3274 histidine kinase. (473 aa)
ACZ75751.1Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: dze:Dd1591_3225 two component transcriptional regulator, winged helix family. (231 aa)
ACZ75752.1Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: dze:Dd1591_3224 histidine kinase. (389 aa)
ACZ75875.1KEGG: dze:Dd1591_3106 two component transcriptional regulator PhoB, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver. (229 aa)
ACZ75876.1KEGG: dze:Dd1591_3105 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: phosphate regulon sensor kinase PhoR; PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein. (440 aa)
rcsCIntegral membrane sensor hybrid histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (962 aa)
rcsBTwo component transcriptional regulator, LuxR family; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. (216 aa)
rcsDMulti-sensor signal transduction histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (889 aa)
ACZ76147.1KEGG: dda:Dd703_1205 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; MASE2 domain protein; SMART: GGDEF domain containing protein. (354 aa)
ACZ76192.1KEGG: dze:Dd1591_2785 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein. (519 aa)
ACZ76206.1Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: dze:Dd1591_2774 two component transcriptional regulator, winged helix family. (248 aa)
ACZ76207.1Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: dze:Dd1591_2773 histidine kinase. (358 aa)
ACZ76217.1PFAM: LrgB family protein; KEGG: dze:Dd1591_2765 LrgB family protein. (231 aa)
ACZ76218.1PFAM: LrgA family protein; KEGG: dze:Dd1591_2764 LrgA family protein. (138 aa)
ACZ76219.1Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: pst:PSPTO_5548 LuxR family DNA-binding response regulator. (217 aa)
ACZ76220.1Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: psb:Psyr_5089 sensor histidine kinase. (356 aa)
ACZ76221.1PFAM: ABC nitrate/sulphonate/bicarbonate family transporter, ATPase subunit; ABC transporter related; SMART: AAA ATPase; KEGG: psp:PSPPH_5173 ABC transporter, ATP-binding protein. (441 aa)
ACZ76222.1PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pst:PSPTO_5551 ABC transporter, permease protein. (584 aa)
ACZ76350.1Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: dze:Dd1591_1518 two component transcriptional regulator, LuxR family. (218 aa)
ACZ76475.1Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: dze:Dd1591_1646 diguanylate phosphodiesterase. (501 aa)
ACZ76616.1Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: dze:Dd1591_1789 histidine kinase. (451 aa)
ACZ76617.1Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: dze:Dd1591_1790 two component transcriptional regulator, winged helix family. (247 aa)
ACZ76676.1Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: dze:Dd1591_1848 two component transcriptional regulator, LuxR family. (215 aa)
ACZ76677.1Integral membrane sensor signal transduction histidine kinase; KEGG: dze:Dd1591_1849 histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein. (602 aa)
ACZ76750.1KEGG: dze:Dd1591_1894 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase dimerisation and phosphoacceptor region; PAS fold-4 domain protein; PAS fold domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein. (488 aa)
ACZ76751.1Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: dze:Dd1591_1895 two component transcriptional regulator, LuxR family. (213 aa)
ACZ76784.1Integral membrane sensor signal transduction histidine kinase; PFAM: PhoQ Sensor domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: dze:Dd1591_1938 histidine kinase. (487 aa)
ACZ76785.1Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: dze:Dd1591_1939 two component transcriptional regulator, winged helix family. (222 aa)
ACZ76793.1KEGG: dze:Dd1591_1946 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; GAF domain protein. (722 aa)
rssBResponse regulator receiver protein; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. (338 aa)
ACZ77003.1PFAM: Patatin; KEGG: dze:Dd1591_2202 patatin. (302 aa)
ACZ77004.1PFAM: SEC-C motif domain protein; KEGG: dze:Dd1591_2203 sec-C motif domain protein; Belongs to the UPF0225 family. (155 aa)
ACZ77343.1PFAM: LrgA family protein; KEGG: dze:Dd1591_2542 LrgA family protein. (136 aa)
ACZ77344.1PFAM: LrgB family protein; KEGG: dze:Dd1591_2543 LrgB family protein. (232 aa)
ACZ77392.1KEGG: dze:Dd1591_2643 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein. (471 aa)
ACZ77484.1Two component transcriptional regulator, winged helix family; KEGG: ypy:YPK_2192 two component heavy metal response transcriptional regulator; TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver. (231 aa)
ACZ77485.1Multi-sensor signal transduction histidine kinase; Member of a two-component regulatory system. (462 aa)
ACZ77713.1Diguanylate cyclase; KEGG: kpe:KPK_3558 putative membrane-bound diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein. (294 aa)
ACZ77754.1Transcriptional regulator, LuxR family; PFAM: Autoinducer-binding domain protein; regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: psp:PSPPH_4238 LuxR family transcriptional regulator. (250 aa)
ACZ77756.1KEGG: dda:Dd703_0347 diguanylate cyclase with hemerythrin-like metal-binding domain; TIGRFAM: diguanylate cyclase; hemerythrin-like metal-binding protein; PFAM: GGDEF domain containing protein; Hemerythrin HHE cation binding domain protein; SMART: GGDEF domain containing protein. (512 aa)
ACZ77836.1TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter domain protein; Na+ dependent nucleoside transporter; nucleoside recognition domain protein; KEGG: dze:Dd1591_1207 nucleoside transporter. (393 aa)
mdtATIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: dze:Dd1591_1206 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (421 aa)
mdtBPFAM: acriflavin resistance protein; KEGG: dze:Dd1591_1205 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily. (1046 aa)
mdtCPFAM: acriflavin resistance protein; KEGG: dze:Dd1591_1204 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily. (1029 aa)
mdtDPFAM: major facilitator superfamily MFS_1; KEGG: dze:Dd1591_1203 major facilitator superfamily MFS_1. (467 aa)
ACZ77841.1Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: dze:Dd1591_1202 histidine kinase. (452 aa)
ACZ77842.1Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: dze:Dd1591_1201 two component transcriptional regulator, winged helix family. (243 aa)
ACZ77843.1PFAM: Glutathione S-transferase domain; KEGG: dze:Dd1591_1200 glutathione transferase. (320 aa)
ACZ77844.1PFAM: peptidase U32; KEGG: dze:Dd1591_1199 peptidase U32. (458 aa)
ACZ77934.1KEGG: dze:Dd1591_1075 diguanylate cyclase with PAS/PAC and GAF sensors; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; GAF domain protein; SMART: GGDEF domain containing protein; GAF domain protein; PAC repeat-containing protein. (505 aa)
ACZ77935.1Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: dze:Dd1591_1074 diguanylate phosphodiesterase. (263 aa)
ACZ78163.1PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein; KEGG: dze:Dd1591_0813 Hpt sensor hybrid histidine kinase. (922 aa)
ACZ78230.1KEGG: dze:Dd1591_0754 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein. (483 aa)
ACZ78279.1KEGG: dze:Dd1591_0694 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Cache domain protein; SMART: GGDEF domain containing protein. (514 aa)
ACZ78428.1KEGG: dze:Dd1591_0538 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein. (381 aa)
ACZ78435.1Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein; KEGG: dze:Dd1591_0531 two component transcriptional regulator, winged helix family. (238 aa)
ACZ78579.1Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: dze:Dd1591_0310 two component transcriptional regulator, winged helix family. (222 aa)
ACZ78580.1Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: dze:Dd1591_0309 histidine kinase. (376 aa)
ACZ78621.1KEGG: dda:Dd703_0347 diguanylate cyclase with hemerythrin-like metal-binding domain; TIGRFAM: diguanylate cyclase; hemerythrin-like metal-binding protein; PFAM: GGDEF domain containing protein; Hemerythrin HHE cation binding domain protein; SMART: GGDEF domain containing protein. (521 aa)
ACZ78645.1Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: dze:Dd1591_0245 histidine kinase. (470 aa)
ACZ78646.1Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: dze:Dd1591_0244 two component transcriptional regulator, winged helix family. (239 aa)
ACZ78827.1Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: dze:Dd1591_4033 two component transcriptional regulator, winged helix family. (232 aa)
ACZ78828.1Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: dze:Dd1591_4034 histidine kinase. (456 aa)
ACZ79008.1KEGG: dze:Dd1591_4204 diguanylate cyclase with PAS/PAC and GAF sensors; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; GAF domain protein; PAS fold-3 domain protein; SMART: GGDEF domain containing protein; GAF domain protein; PAS domain containing protein; PAC repeat-containing protein. (771 aa)
Your Current Organism:
Dickeya zeae
NCBI taxonomy Id: 590409
Other names: D. zeae Ech586, Dickeya dadantii Ech586, Dickeya zeae Ech586
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