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| | ACZ74944.1 | KEGG: dze:Dd1591_0044 hypothetical protein. (331 aa) |
| | ACZ75053.1 | PFAM: glycosyl transferase family 2; KEGG: dze:Dd1591_3955 glycosyl transferase family 2. (263 aa) |
| | ACZ75054.1 | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (427 aa) |
| | ACZ75055.1 | PFAM: glycosyl transferase group 1; KEGG: dze:Dd1591_3953 glycosyl transferase group 1. (374 aa) |
| | ACZ75056.1 | PFAM: glycosyl transferase family 9; KEGG: dze:Dd1591_3952 glycosyl transferase family 9. (369 aa) |
| | ACZ75058.1 | PFAM: glycosyl transferase group 1; KEGG: dze:Dd1591_3950 glycosyl transferase group 1. (372 aa) |
| | ACZ75059.1 | TIGRFAM: lipopolysaccharide heptosyltransferase III; PFAM: glycosyl transferase family 9; KEGG: dze:Dd1591_3949 lipopolysaccharide heptosyltransferase III. (361 aa) |
| | ACZ75060.1 | TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9; KEGG: dze:Dd1591_3948 lipopolysaccharide heptosyltransferase I. (323 aa) |
| | ACZ75061.1 | TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9; KEGG: dze:Dd1591_3947 lipopolysaccharide heptosyltransferase II. (350 aa) |
| | pagP | Antimicrobial peptide resistance and lipid A acylation PagP; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. (219 aa) |
| | ACZ75186.1 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. (188 aa) |
| | ACZ75187.1 | KEGG: dze:Dd1591_3810 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein. (328 aa) |
| | ACZ75231.1 | PFAM: aldo/keto reductase; KEGG: dze:Dd1591_3766 2,5-didehydrogluconate reductase. (281 aa) |
| | ACZ75408.1 | KEGG: dze:Dd1591_3560 undecaprenyl-phosphate glucose phosphotransferase; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase. (468 aa) |
| | ACZ75411.1 | PFAM: lipopolysaccharide biosynthesis protein; KEGG: dze:Dd1591_3557 lipopolysaccharide biosynthesis protein. (715 aa) |
| | ACZ75415.1 | PFAM: glycosyl transferase group 1; KEGG: dze:Dd1591_3553 glycosyl transferase group 1. (403 aa) |
| | ACZ75416.1 | PFAM: glycosyl transferase group 1; Protein of unknown function DUF1972; KEGG: dze:Dd1591_3552 glycosyl transferase group 1. (367 aa) |
| | ACZ75543.1 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (287 aa) |
| | ACZ75545.1 | KEGG: dda:Dd703_3281 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase. (470 aa) |
| | ACZ75551.1 | KEGG: rpc:RPC_4203 UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (375 aa) |
| | ACZ75552.1 | PFAM: glycosyl transferase group 1; KEGG: rpc:RPC_4204 glycosyl transferase, group 1. (402 aa) |
| | ACZ75554.1 | PFAM: glycosyl transferase group 1; KEGG: cyc:PCC7424_0332 glycosyl transferase group 1. (399 aa) |
| | ACZ75555.1 | PFAM: glycosyl transferase group 1; KEGG: bpy:Bphyt_0910 glycosyl transferase group 1. (634 aa) |
| | ACZ75556.1 | PFAM: glycosyl transferase group 1; KEGG: rpc:RPC_4195 glycosyl transferase, group 1. (1006 aa) |
| | ACZ75559.1 | Hypothetical protein; KEGG: ara:Arad_4833 glycosyltransferase. (361 aa) |
| | ACZ75560.1 | PFAM: glycosyl transferase group 1; KEGG: ecr:ECIAI1_2099 mannosyltransferase. (460 aa) |
| | ACZ75561.1 | PFAM: glycosyl transferase group 1; KEGG: ara:Arad_4842 glycosyl transferase protein. (327 aa) |
| | ACZ75562.1 | PFAM: glycosyl transferase group 1; KEGG: dda:Dd703_3274 glycosyl transferase group 1. (375 aa) |
| | ACZ75563.1 | PFAM: polysaccharide biosynthesis protein CapD; KEGG: dze:Dd1591_3389 polysaccharide biosynthesis protein CapD. (629 aa) |
| | ACZ75564.1 | PFAM: NAD-dependent epimerase/dehydratase; KEGG: dze:Dd1591_3388 NAD-dependent epimerase/dehydratase. (300 aa) |
| | ACZ75565.1 | PFAM: sugar transferase; KEGG: dze:Dd1591_3387 sugar transferase. (182 aa) |
| | lpxP | Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily. (306 aa) |
| | ACZ75615.1 | PFAM: acyltransferase 3; KEGG: bps:BPSS0268 O-antigen acetylase. (683 aa) |
| | lpxD | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (341 aa) |
| | fabZ | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (151 aa) |
| | lpxA | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (262 aa) |
| | lpxB | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (382 aa) |
| | gpmA | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa) |
| | ACZ76121.1 | KEGG: dze:Dd1591_2865 capsular exopolysaccharide family; TIGRFAM: capsular exopolysaccharide family; PFAM: lipopolysaccharide biosynthesis protein. (723 aa) |
| | ACZ76122.1 | PFAM: glycosyl transferase group 1; KEGG: dze:Dd1591_2864 glycosyl transferase group 1. (384 aa) |
| | ACZ76123.1 | PFAM: glycosyl transferase group 1; KEGG: dze:Dd1591_2863 glycosyl transferase group 1. (400 aa) |
| | ACZ76124.1 | PFAM: glycosyl transferase group 1; KEGG: dze:Dd1591_2862 glycosyl transferase group 1. (344 aa) |
| | ACZ76125.1 | PFAM: glycosyl transferase family 2; KEGG: dze:Dd1591_2861 glycosyl transferase family 2. (305 aa) |
| | ACZ76126.1 | KEGG: dze:Dd1591_2860 undecaprenyl-phosphate glucose phosphotransferase; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase. (468 aa) |
| | ACZ76128.1 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (289 aa) |
| | ACZ76130.1 | KEGG: dze:Dd1591_2856 dTDP-4-dehydrorhamnose reductase; TIGRFAM: dTDP-4-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase. (285 aa) |
| | ACZ76132.1 | PFAM: polysaccharide biosynthesis protein; KEGG: dze:Dd1591_2854 polysaccharide biosynthesis protein. (423 aa) |
| | ACZ76133.1 | Glycosyltransferase; KEGG: dze:Dd1591_2853 glycosyltransferase. (278 aa) |
| | ACZ76134.1 | KEGG: dze:Dd1591_2852 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Nucleotidyl transferase; mannose-6-phosphate isomerase type II. (475 aa) |
| | ACZ76136.1 | PFAM: NAD-dependent epimerase/dehydratase; KEGG: dze:Dd1591_2850 NAD-dependent epimerase/dehydratase. (335 aa) |
| | ACZ76137.1 | KEGG: dze:Dd1591_2849 nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (388 aa) |
| | ACZ76141.1 | KEGG: dze:Dd1591_2845 putative lipoprotein. (210 aa) |
| | ACZ76143.1 | PFAM: protein of unknown function DUF940 membrane lipoprotein putative; KEGG: dze:Dd1591_2843 protein of unknown function DUF940 membrane lipoprotein putative. (713 aa) |
| | ACZ76413.1 | PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: dze:Dd1591_1583 DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (375 aa) |
| | mdoG | Periplasmic glucan biosynthesis protein MdoG; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (522 aa) |
| | mdoH | Glycosyl transferase family 2; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (849 aa) |
| | lpxL | Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (306 aa) |
| | ACZ76516.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa) |
| | ACZ76607.1 | PFAM: acyltransferase 3; KEGG: bcj:BCAM1333 putative exopolysaccharide acyltransferase. (390 aa) |
| | ACZ76675.1 | PFAM: acyltransferase 3; KEGG: dze:Dd1591_1847 acyltransferase 3. (426 aa) |
| | ACZ76833.1 | KEGG: dze:Dd1591_1985 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. (453 aa) |
| | kdsA | TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: dze:Dd1591_2076 2-dehydro-3-deoxyphosphooctonate aldolase. (284 aa) |
| | ACZ76919.1 | PFAM: acyltransferase 3; KEGG: dze:Dd1591_2117 acyltransferase 3. (334 aa) |
| | ACZ76928.1 | TIGRFAM: mannosyl-3-phosphoglycerate phosphatase family; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; KEGG: dze:Dd1591_2128 mannosyl-3-phosphoglycerate phosphatase family. (277 aa) |
| | lpxM | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. (328 aa) |
| | kdsB | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (250 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (337 aa) |
| | ACZ77222.1 | PFAM: NLP/P60 protein; KEGG: dze:Dd1591_2431 NLP/P60 protein. (191 aa) |
| | ACZ77269.1 | PFAM: GlpM family protein; KEGG: dze:Dd1591_2468 GlpM family protein. (113 aa) |
| | ACZ77647.1 | KEGG: dze:Dd1591_1330 putative avirulence protein. (618 aa) |
| | ACZ77696.1 | PFAM: aldo/keto reductase; KEGG: efe:EFER_2672 putative aldo-keto reductase. (283 aa) |
| | lpxH | UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (240 aa) |
| | ACZ77808.1 | KEGG: dze:Dd1591_1241 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. (456 aa) |
| | ACZ78057.1 | PFAM: membrane bound O-acyl transferase MBOAT family protein; KEGG: dze:Dd1591_0951 membrane bound O-acyl transferase MBOAT family protein; Belongs to the membrane-bound acyltransferase family. (372 aa) |
| | lpxC | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (305 aa) |
| | fbp | Fructose-bisphosphatase; PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: dze:Dd1591_0499 fructose-bisphosphatase. (334 aa) |
| | pgi | PFAM: phosphoglucose isomerase (PGI); KEGG: dze:Dd1591_0373 glucose-6-phosphate isomerase; Belongs to the GPI family. (549 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (539 aa) |
| | ACZ78648.1 | PFAM: sulfatase; KEGG: dze:Dd1591_0242 sulfatase. (673 aa) |
| | glgA | Glycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (477 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (428 aa) |
| | glgB | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (727 aa) |
| | wecG | Glycosyl transferase, WecB/TagA/CpsF family; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis. (244 aa) |
| | wzyE | WzyE family protein; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. (447 aa) |
| | wecF | 4-alpha-L-fucosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. (361 aa) |
| | wzxE | Polysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. (416 aa) |
| | wecE | TDP-4-keto-6-deoxy-D-glucose transaminase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. (376 aa) |
| | wecD | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. (234 aa) |
| | ACZ78726.1 | TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: dze:Dd1591_0161 nucleotide sugar dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (419 aa) |
| | wecB | UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. (376 aa) |
| | wzzE | Lipopolysaccharide biosynthesis protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. (344 aa) |
| | wecA | Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). (357 aa) |
| | ACZ78776.1 | KEGG: dze:Dd1591_0107 fructose-1,6-bisphosphatase, class II; TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein. (336 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (256 aa) |
| | ACZ78884.1 | PFAM: cellulose synthase subunit D; KEGG: dze:Dd1591_4080 cellulose synthase operon protein D. (155 aa) |
| | ACZ78885.1 | PFAM: cellulose synthase operon C domain protein; Tetratricopeptide TPR_4; KEGG: dze:Dd1591_4081 cellulose synthase operon C domain protein. (1300 aa) |
| | ACZ78886.1 | Cellulose synthase BcsB; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family. (842 aa) |
| | ACZ78887.1 | Cellulose synthase catalytic subunit (UDP-forming); Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose. (696 aa) |
| | glmU | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (456 aa) |
| | arnB | DegT/DnrJ/EryC1/StrS aminotransferase; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily. (380 aa) |
| | arnC | Glycosyl transferase family 2; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. (327 aa) |
| | arnA | NAD-dependent epimerase/dehydratase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily. (663 aa) |
| | arnD | Polysaccharide deacetylase; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily. (299 aa) |
| | arnT | Glycosyl transferase family 39; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. (552 aa) |
| | arnE | Protein of unknown function DUF6 transmembrane; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family. (113 aa) |
| | arnF | Conserved hypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family. (132 aa) |
