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hisG hisG hisD hisD hisC hisC hisB hisB hisH hisH hisA hisA hisF hisF hisI hisI hutU hutU hutH hutH ACZ77789.1 ACZ77789.1 ACZ77795.1 ACZ77795.1 hutI hutI ACZ77797.1 ACZ77797.1 ACZ78189.1 ACZ78189.1 ACZ78617.1 ACZ78617.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (299 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (436 aa)
hisCTIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: dze:Dd1591_2331 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (356 aa)
hisBKEGG: dze:Dd1591_2332 histidinol-phosphatase; TIGRFAM: histidinol-phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: imidazoleglycerol-phosphate dehydratase; Polynucleotide kinase 3 phosphatase central region; In the N-terminal section; belongs to the histidinol- phosphatase family. (355 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (196 aa)
hisAKEGG: dze:Dd1591_2334 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. (245 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (258 aa)
hisITIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; phosphoribosyl-AMP cyclohydrolase; KEGG: dze:Dd1591_2336 phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family. (204 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (563 aa)
hutHKEGG: dze:Dd1591_1264 histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase. (520 aa)
ACZ77789.1KEGG: dze:Dd1591_1260 histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase. (514 aa)
ACZ77795.1TIGRFAM: formiminoglutamate deiminase; PFAM: amidohydrolase; KEGG: dze:Dd1591_1254 formiminoglutamate deiminase. (454 aa)
hutIImidazolonepropionase; KEGG: dze:Dd1591_1253 imidazolonepropionase; TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase. (404 aa)
ACZ77797.1TIGRFAM: N-formylglutamate amidohydrolase; PFAM: N-formylglutamate amidohydrolase; KEGG: dze:Dd1591_1252 N-formylglutamate amidohydrolase. (266 aa)
ACZ78189.1PFAM: aminotransferase class I and II; KEGG: ilo:IL1836 histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (343 aa)
ACZ78617.1KEGG: dze:Dd1591_0272 glutamate decarboxylase. (456 aa)
Your Current Organism:
Dickeya zeae
NCBI taxonomy Id: 590409
Other names: D. zeae Ech586, Dickeya dadantii Ech586, Dickeya zeae Ech586
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