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Celf_3512 Celf_3512 tadA tadA Celf_3374 Celf_3374 Celf_3224 Celf_3224 purQ purQ Celf_3093 Celf_3093 Celf_3076 Celf_3076 Celf_3064 Celf_3064 Celf_2997 Celf_2997 Celf_2899 Celf_2899 arcA arcA purH purH def def Celf_0893 Celf_0893 Celf_0845 Celf_0845 Celf_0821 Celf_0821 Celf_0747 Celf_0747 Celf_0744 Celf_0744 cheB cheB folE folE Celf_0378 Celf_0378 Celf_0374 Celf_0374 dcd dcd Celf_0109 Celf_0109 Celf_0072 Celf_0072 Celf_0071 Celf_0071 hutI hutI Celf_2137 Celf_2137 nadE nadE def-2 def-2 Celf_2792 Celf_2792 Celf_2814 Celf_2814 Celf_2858 Celf_2858 Celf_2861 Celf_2861 Celf_2889 Celf_2889 Celf_2898 Celf_2898 purU purU folD folD Celf_1222 Celf_1222 Celf_1339 Celf_1339 Celf_1455 Celf_1455 Celf_1456 Celf_1456 Celf_1499 Celf_1499 Celf_1620 Celf_1620 hisH hisH pyrG pyrG Celf_1790 Celf_1790 hisI hisI Celf_1815 Celf_1815 Celf_1949 Celf_1949 ribB ribB Celf_1965 Celf_1965 pyrC pyrC pdxT pdxT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Celf_3512KEGG: hypothetical protein. (211 aa)
tadACMP/dCMP deaminase zinc-binding protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (171 aa)
Celf_3374PFAM: L-asparaginase II; KEGG: L-asparaginase II. (325 aa)
Celf_3224PFAM: Amidohydrolase 3; KEGG: amidohydrolase 3. (497 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (231 aa)
Celf_3093PFAM: peptidase S45 penicillin amidase; KEGG: peptidase S45 penicillin amidase. (898 aa)
Celf_3076PFAM: isochorismatase hydrolase; KEGG: nicotinamidase-like amidase. (196 aa)
Celf_3064PFAM: peptidase S45 penicillin amidase; KEGG: peptidase S45 penicillin amidase. (805 aa)
Celf_2997KEGG: sco:SCO6307 cyclase SCIF309c. (339 aa)
Celf_2899PFAM: LmbE family protein; KEGG: LmbE family protein. (315 aa)
arcAKEGG: sco:SCO0613 arginine deiminase; PFAM: amidinotransferase. (429 aa)
purHSMART: AICARFT/IMPCHase bienzyme formylation region; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein. (535 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (321 aa)
Celf_0893KEGG: histone deacetylase; PFAM: histone deacetylase superfamily. (400 aa)
Celf_0845LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (265 aa)
Celf_0821KEGG: response regulator receiver protein; PFAM: response regulator receiver; LmbE family protein; SMART: response regulator receiver. (363 aa)
Celf_0747KEGG: hypothetical protein. (283 aa)
Celf_0744PFAM: amidinotransferase; KEGG: amidinotransferase. (281 aa)
cheBResponse regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (382 aa)
folETIGRFAM: GTP cyclohydrolase I; KEGG: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase. (211 aa)
Celf_0378PFAM: glutamine amidotransferase class-II; KEGG: cai:Caci_6587 hypothetical protein. (278 aa)
Celf_0374KEGG: glycoside hydrolase family 11; PFAM: glycoside hydrolase family 11; cellulose-binding family II; polysaccharide deacetylase; SMART: cellulose-binding family II; Belongs to the glycosyl hydrolase 11 (cellulase G) family. (645 aa)
dcdDeoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (210 aa)
Celf_0109KEGG: hypothetical protein. (655 aa)
Celf_0072TIGRFAM: amidase, hydantoinase/carbamoylase family; KEGG: sro:Sros_1779 allantoate amidohydrolase; PFAM: peptidase M20. (409 aa)
Celf_0071KEGG: nml:Namu_0039 formiminoglutamate deiminase; TIGRFAM: formiminoglutamate deiminase; PFAM: amidohydrolase. (445 aa)
hutITIGRFAM: imidazolonepropionase; KEGG: bcv:Bcav_1839 imidazolonepropionase; PFAM: amidohydrolase. (388 aa)
Celf_2137PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: cai:Caci_8299 arginase/agmatinase/formiminoglutamase; Belongs to the arginase family. (298 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (555 aa)
def-2Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (166 aa)
Celf_2792KEGG: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase. (420 aa)
Celf_2814KEGG: nca:Noca_3751 hypothetical protein. (111 aa)
Celf_2858TIGRFAM: adenosine deaminase; KEGG: adenosine deaminase; PFAM: adenosine/AMP deaminase. (375 aa)
Celf_2861KEGG: cytidine deaminase; TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding. (131 aa)
Celf_2889KEGG: succinyl-diaminopimelate desuccinylase; TIGRFAM: succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein. (366 aa)
Celf_2898KEGG: hypothetical protein. (139 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (291 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (293 aa)
Celf_1222KEGG: krh:KRH_06000 hypothetical protein. (246 aa)
Celf_1339PFAM: amidohydrolase; KEGG: amidohydrolase, imidazolonepropionase. (418 aa)
Celf_1455PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. (282 aa)
Celf_1456KEGG: dihydropyrimidinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase. (471 aa)
Celf_1499PFAM: amidohydrolase; KEGG: amidohydrolase. (365 aa)
Celf_1620PFAM: protein of unknown function DUF152; KEGG: xce:Xcel_1288 protein of unknown function DUF152; Belongs to the multicopper oxidase YfiH/RL5 family. (248 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (226 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (556 aa)
Celf_1790PFAM: protein of unknown function DUF245 domain protein; KEGG: protein of unknown function DUF245 domain protein. (533 aa)
hisIPhosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (138 aa)
Celf_1815PFAM: peptidase C14 caspase catalytic subunit p20; KEGG: sus:Acid_7633 peptidase C14, caspase catalytic subunit P20. (302 aa)
Celf_1949PFAM: Amidohydrolase 3; KEGG: amidohydrolase 3. (545 aa)
ribBGTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. (451 aa)
Celf_1965Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (395 aa)
pyrCDihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (436 aa)
pdxTSNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (201 aa)
Your Current Organism:
Cellulomonas fimi
NCBI taxonomy Id: 590998
Other names: C. fimi ATCC 484, Cellulomonas fimi ATCC 484, Cellulomonas fimi DSM 20113, Cellulomonas fimi str. ATCC 484, Cellulomonas fimi strain ATCC 484
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