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| | Celf_2297 | KEGG: bcv:Bcav_1210 transferase hexapeptide repeat containing protein. (141 aa) |
| | Celf_2596 | PFAM: sugar isomerase (SIS); KEGG: sco:SCO6186 phosphoheptose isomerase. (243 aa) |
| | Celf_2683 | KEGG: gob:Gobs_1800 glutamine amidotransferase. (244 aa) |
| | atpC | ATPase, F1 complex, delta/epsilon subunit-like protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. (97 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (493 aa) |
| | atpG | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (299 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (542 aa) |
| | atpH | ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (270 aa) |
| | atpF | ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (197 aa) |
| | atpE | ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (83 aa) |
| | atpB | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (267 aa) |
| | Celf_2838 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: adenylate/guanylate cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase. (378 aa) |
| | Celf_2856 | KEGG: cellulose-binding family II; PFAM: cellulose-binding family II; transferase hexapeptide repeat containing protein; SMART: cellulose-binding family II. (765 aa) |
| | Celf_2858 | TIGRFAM: adenosine deaminase; KEGG: adenosine deaminase; PFAM: adenosine/AMP deaminase. (375 aa) |
| | Celf_2886 | KEGG: putative integral membrane protein. (419 aa) |
| | ispH | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (347 aa) |
| | Celf_2995 | PFAM: Cupin 2 conserved barrel domain protein; KEGG: cupin 2 conserved barrel domain protein. (358 aa) |
| | Celf_3041 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cms:CMS_0082 putative glycosyl transferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (265 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (327 aa) |
| | glmU | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (550 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (314 aa) |
| | Celf_3076 | PFAM: isochorismatase hydrolase; KEGG: nicotinamidase-like amidase. (196 aa) |
| | Celf_3090 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (412 aa) |
| | Celf_3119 | KEGG: kra:Krad_4356 protein of unknown function UPF0157. (158 aa) |
| | purM | TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; KEGG: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. (373 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (515 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (790 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (231 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (87 aa) |
| | purC | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: phosphoribosylaminoimidazole-succinocarboxamides ynthase; PFAM: SAICAR synthetase. (309 aa) |
| | purD | TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family. (431 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (191 aa) |
| | Celf_3394 | PFAM: metallophosphoesterase; KEGG: metallophosphoesterase. (312 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (211 aa) |
| | Celf_3501 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (326 aa) |
| | Celf_3563 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ami:Amir_2003 glyoxalase/bleomycin resistance protein/dioxygenase. (141 aa) |
| | Celf_2561 | TIGRFAM: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; KEGG: art:Arth_1381 pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component. (392 aa) |
| | Celf_3787 | KEGG: inositol 1-phosphate synthase; TIGRFAM: inositol 1-phosphate synthase; PFAM: Myo-inositol-1-phosphate synthase; Myo-inositol-1-phosphate synthase GAPDH domain protein. (363 aa) |
| | Celf_3739 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (436 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (158 aa) |
| | Celf_3737 | KEGG: bcv:Bcav_2808 molybdopterin-guanine dinucleotide biosynthesis protein. (226 aa) |
| | Celf_3736 | KEGG: tcu:Tcur_2267 molybdopterin-guanine dinucleotide biosynthesis protein A-like protein. (91 aa) |
| | Celf_3735 | PFAM: thiamineS protein; KEGG: mab:MAB_0870c putative molybdenum cofactor biosynthesis protein D2 (MoaD2) / thiamineS. (87 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (367 aa) |
| | Celf_3731 | PFAM: molybdopterin biosynthesis MoaE protein; KEGG: stp:Strop_4546 molybdopterin biosynthesis MoaE protein. (140 aa) |
| | Celf_3730 | Molybdenum cofactor synthesis domain protein; KEGG: kse:Ksed_19280 molybdopterin adenylyltransferase; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain. (165 aa) |
| | Celf_3685 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bcv:Bcav_1646 glyoxalase/bleomycin resistance protein/dioxygenase. (139 aa) |
| | Celf_3604 | PFAM: diacylglycerol kinase catalytic region; KEGG: diacylglycerol kinase catalytic region. (386 aa) |
| | Celf_0057 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sgr:SGR_1436 hypothetical protein. (126 aa) |
| | Celf_0216 | KEGG: phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase. (192 aa) |
| | Celf_0243 | KEGG: adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Adenylosuccinate lyase domain-containing protein; fumarate lyase. (489 aa) |
| | Celf_0252 | PFAM: dehydrogenase E1 component; manually curated; KEGG: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; TIGRFAM: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit. (385 aa) |
| | Celf_0272 | KEGG: saq:Sare_4058 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase. (350 aa) |
| | Celf_0289 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: glyoxalase/bleomycin resistance protein/dioxygenase. (135 aa) |
| | Celf_0299 | Hypothetical protein; KEGG: scb:SCAB_77981 putative GntR family regulator. (298 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (210 aa) |
| | Celf_0371 | PFAM: protein of unknown function DUF179; KEGG: sco:SCO2948 hypothetical protein; Belongs to the UPF0301 (AlgH) family. (200 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (230 aa) |
| | Celf_0558 | TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (183 aa) |
| | folE | TIGRFAM: GTP cyclohydrolase I; KEGG: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase. (211 aa) |
| | Celf_0564 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sma:SAV_733 hypothetical protein. (207 aa) |
| | Celf_0573 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (578 aa) |
| | Celf_0575 | TIGRFAM: nicotinate-nucleotide pyrophosphorylase; KEGG: nicotinate-nucleotide pyrophosphorylase (carboxylating); PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. (295 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (254 aa) |
| | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (165 aa) |
| | Celf_0648 | PFAM: peptidase C26; KEGG: glutamine amidotransferase class-I. (249 aa) |
| | Celf_0674 | TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; KEGG: type III secretion system ATPase, FliI/YscN; SMART: AAA ATPase. (444 aa) |
| | Celf_0809 | PFAM: NUDIX hydrolase; KEGG: bcv:Bcav_0671 NUDIX hydrolase. (157 aa) |
| | Celf_0822 | PFAM: protein of unknown function DUF201; KEGG: protein of unknown function DUF201. (331 aa) |
| | araA | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (502 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (190 aa) |
| | coaA | TIGRFAM: pantothenate kinase; KEGG: pantothenate kinase. (316 aa) |
| | Celf_1052 | KEGG: putative fructose transport system kinase. (224 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (504 aa) |
| | Celf_1076 | KEGG: IMP dehydrogenase family protein; TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase. (374 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (425 aa) |
| | Celf_1086 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (703 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (527 aa) |
| | Celf_1110 | KEGG: phosphoribulokinase / uridine kinase family. (227 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (226 aa) |
| | purH | SMART: AICARFT/IMPCHase bienzyme formylation region; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein. (535 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (291 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (293 aa) |
| | Celf_1236 | KEGG: hypothetical protein. (214 aa) |
| | Celf_1357 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (467 aa) |
| | Celf_1456 | KEGG: dihydropyrimidinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase. (471 aa) |
| | Celf_1467 | PFAM: phosphoribosyltransferase; KEGG: phosphoribosyltransferase. (172 aa) |
| | Celf_1475 | KEGG: putative NadR-like transcriptional regulator. (362 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (247 aa) |
| | Celf_1518 | PFAM: phosphatidate cytidylyltransferase; KEGG: phosphatidate cytidylyltransferase. (283 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (387 aa) |
| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (386 aa) |
| | Celf_1538 | KEGG: riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. (346 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (281 aa) |
| | Celf_1560 | KEGG: CDP-diacylglycerol/glycerol-3-phosphate3-phospha tidyltransferase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (235 aa) |
| | Celf_1561 | PFAM: CinA domain protein; KEGG: CinA domain protein; Belongs to the CinA family. (161 aa) |
| | thiM | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (274 aa) |
| | thiE | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (230 aa) |
| | Celf_1657 | KEGG: phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; TENA/THI-4 domain-containing protein. (507 aa) |
| | Celf_1669 | KEGG: hypothetical protein. (209 aa) |
| | nadK | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (293 aa) |
| | Celf_1678 | PFAM: Thiamin pyrophosphokinase catalytic domain-containing protein; KEGG: thiamin pyrophosphokinase catalytic region. (395 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (556 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (209 aa) |
| | cmk | KEGG: cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. (242 aa) |
| | Celf_1883 | KEGG: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase. (230 aa) |
| | Celf_1930 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (194 aa) |
| | Celf_1951 | KEGG: diacylglycerol kinase catalytic region; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region. (304 aa) |
| | Celf_1972 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (396 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (191 aa) |
| | pyrF | TIGRFAM: orotidine 5'-phosphate decarboxylase; KEGG: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (292 aa) |
| | carB | KEGG: carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; Belongs to the CarB family. (1114 aa) |
| | carA | KEGG: carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. (397 aa) |
| | Celf_1979 | KEGG: hypothetical protein. (194 aa) |
| | pyrC | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (436 aa) |
| | pyrB | KEGG: aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (331 aa) |
| | Celf_2024 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (777 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (195 aa) |
| | pdxT | SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (201 aa) |
| | pdxS | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (310 aa) |
| | Celf_2040 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (203 aa) |
| | dxs | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (627 aa) |
| | Celf_2133 | TIGRFAM: IMP dehydrogenase family protein; KEGG: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein. (484 aa) |
| | Celf_2134 | PFAM: glutamine amidotransferase class-I; KEGG: glutamine amidotransferase class-I. (229 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (155 aa) |
| | Celf_2153 | KEGG: thymidine kinase; PFAM: thymidine kinase. (223 aa) |
| | Celf_2172 | KEGG: phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase. (259 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (400 aa) |
| | pyrD | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (354 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (555 aa) |
| | Celf_2303 | Diacylglycerol kinase catalytic region; KEGG: nca:Noca_0173 phosphoesterase, PA-phosphatase related; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region. (326 aa) |
| | nadD | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (199 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (164 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (339 aa) |
| | gpsA | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: glycerol-3-phosphate dehydrogenase (NAD(P)(+)); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (347 aa) |
| | Celf_2454 | KEGG: phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase. (246 aa) |
| | Celf_2492 | KEGG: hypothetical protein. (260 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (178 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (388 aa) |
