STRINGSTRING
uhpB uhpB ANA27671.1 ANA27671.1 gyrB gyrB glnL glnL cpxA cpxA envZ envZ ANA31263.1 ANA31263.1 parE parE ANA31128.1 ANA31128.1 barA barA tctE tctE qseE qseE narX_1 narX_1 rcsC rcsC yojN yojN ANA30289.1 ANA30289.1 baeS baeS cheA cheA narX_2 narX_2 rstB rstB ANA29503.1 ANA29503.1 ttrS ttrS phoQ phoQ yedV yedV ANA28903.1 ANA28903.1 dpiB dpiB htpG htpG phoR phoR mutL mutL dcuS dcuS pmrB pmrB ANA27926.1 ANA27926.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
uhpBHistidine kinase; Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
ANA27671.1Histidine kinase; Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; Derived by automated computational analysis using gene prediction method: Protein Homology. (912 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (804 aa)
glnLNitrogen regulation protein NR(II); Sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
cpxATwo-component sensor protein; Part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
envZOsmolarity sensor protein; Membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)
ANA31263.1Aerobic respiration control sensor protein ArcB; Sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; Derived by automated computational analysis using gene prediction method: Protein Homology. (778 aa)
parEDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (630 aa)
ANA31128.1Sensor protein QseC; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
barAHistidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology. (918 aa)
tctEHistidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
qseEHistidine kinase; Part of the GlrKR two-component signal transduction system involved in the regulation of glmY; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
narX_1Nitrate/nitrite sensor protein NarQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (566 aa)
rcsCHistidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (948 aa)
yojNPhosphotransfer intermediate protein in two-component regulatory system with RcsBC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (889 aa)
ANA30289.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (561 aa)
baeSHistidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
cheAChemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology. (669 aa)
narX_2Nitrate/nitrite sensor protein NarX; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)
rstBSensor protein RstB; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
ANA29503.1Histidine kinase; Phosphorylates the response regulator SsrB; is involved in the expression of the virulence genes of Salmonella pathogenicity island-2; Derived by automated computational analysis using gene prediction method: Protein Homology. (916 aa)
ttrSHistidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (582 aa)
phoQSensor protein PhoQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)
yedVHistidine kinase; Member of a two-component regulatory system. (452 aa)
ANA28903.1Sensor protein KdpD; Sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (894 aa)
dpiBHistidine kinase; Regulates the expression of citrate fermentation genes; Derived by automated computational analysis using gene prediction method: Protein Homology. (553 aa)
htpGHeat shock protein 90; Molecular chaperone. Has ATPase activity. (624 aa)
phoRPhosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
mutLDNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (618 aa)
dcuSHistidine kinase; C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
pmrBSensor protein BasS/PmrB; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
ANA27926.1Sensor protein ZraS; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
Your Current Organism:
Salmonella enterica diarizonae
NCBI taxonomy Id: 59204
Other names: ATCC 43973, CCUG 30040, CIP 82.31, DSM 14847, NCTC 10060, S. enterica subsp. diarizonae, Salmonella cholerae-suis subsp. diarizonae, Salmonella choleraesuis subsp. diarizonae, Salmonella enterica IIIb, Salmonella enterica serovar IIIb, Salmonella enterica subsp. IIIb, Salmonella enterica subsp. Subsp. IIIb, Salmonella enterica subsp. diarizonae
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