STRINGSTRING
gyrB gyrB ADU67683.1 ADU67683.1 ADU67782.1 ADU67782.1 ADU67821.1 ADU67821.1 ADU68160.1 ADU68160.1 ADU68225.1 ADU68225.1 htpG htpG ADU68458.1 ADU68458.1 ADU68833.1 ADU68833.1 ADU68902.1 ADU68902.1 ADU68919.1 ADU68919.1 ADU69176.1 ADU69176.1 ADU69243.1 ADU69243.1 ADU69331.1 ADU69331.1 ADU69757.1 ADU69757.1 ADU69910.1 ADU69910.1 rcsD rcsD rcsC rcsC ADU70067.1 ADU70067.1 ADU70115.1 ADU70115.1 ADU70141.1 ADU70141.1 ADU70168.1 ADU70168.1 ADU70258.1 ADU70258.1 ADU70396.1 ADU70396.1 parE parE mutL mutL ADU70992.1 ADU70992.1 ADU71070.1 ADU71070.1 ADU71172.1 ADU71172.1 ADU71232.1 ADU71232.1 ADU71254.1 ADU71254.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gyrBDNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (802 aa)
ADU67683.1Integral membrane sensor signal transduction histidine kinase; KEGG: vap:Vapar_4982 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (451 aa)
ADU67782.1Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; KEGG: eta:ETA_03090 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; Hpt domain protein. (777 aa)
ADU67821.1Integral membrane sensor signal transduction histidine kinase; KEGG: eta:ETA_03350 sensor protein BasS/PmrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (352 aa)
ADU68160.1KEGG: ent:Ent638_3378 signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein. (545 aa)
ADU68225.1PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: phosphate regulon sensor kinase PhoR; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; KEGG: eta:ETA_25470 phosphate regulon sensor protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein. (437 aa)
htpGHeat shock protein Hsp90-like protein; Molecular chaperone. Has ATPase activity. (624 aa)
ADU68458.1KEGG: spe:Spro_1285 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; extracellular solute-binding protein family 3; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; extracellular solute-binding protein family 3; response regulator receiver. (1019 aa)
ADU68833.1Integral membrane sensor signal transduction histidine kinase; KEGG: eta:ETA_19710 sensor protein PhoQ; PFAM: PhoQ Sensor domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (486 aa)
ADU68902.1Signal transduction histidine kinase regulating citrate/malate metabolism; KEGG: cko:CKO_03745 sensory histidine kinase DcuS; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein. (564 aa)
ADU68919.1CheA signal transduction histidine kinase; KEGG: eta:ETA_14620 chemotaxis protein CheA; PFAM: ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; CheY binding; Hpt domain protein; CheW domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein. (663 aa)
ADU69176.1Integral membrane sensor signal transduction histidine kinase; KEGG: kpe:KPK_2549 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (433 aa)
ADU69243.1Multi-sensor signal transduction multi-kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; Serine/threonine-protein kinase-like domain; GAF domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; KEGG: bpy:Bphyt_2428 PAS sensor protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; serine/threonine protein kinase; PAC repeat-containing protein; histidine kinase A domain protein. (1857 aa)
ADU69331.1Integral membrane sensor signal transduction histidine kinase; KEGG: eta:ETA_16770 sensor protein RstB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein. (435 aa)
ADU69757.1KEGG: spe:Spro_1028 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver. (854 aa)
ADU69910.1KEGG: eta:ETA_13080 signal transduction histidine-protein kinase BaeS; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein. (461 aa)
rcsDMulti-sensor signal transduction histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (884 aa)
rcsCIntegral membrane sensor hybrid histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (950 aa)
ADU70067.1KEGG: ddc:Dd586_2776 integral membrane sensor signal transduction histidine kinase; PFAM: Two-component sensor kinase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein. (459 aa)
ADU70115.1Signal transduction histidine kinase, LytS; KEGG: eta:ETA_11160 putative sensor protein; PFAM: histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; GAF domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. (571 aa)
ADU70141.1Integral membrane sensor signal transduction histidine kinase; KEGG: eta:ETA_10960 putative two-component system sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein. (457 aa)
ADU70168.1Integral membrane sensor signal transduction histidine kinase; KEGG: spe:Spro_3489 nitrate/nitrite sensor protein NarQ; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein. (561 aa)
ADU70258.1Integral membrane sensor signal transduction histidine kinase; KEGG: eta:ETA_10080 putative 2-component sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (475 aa)
ADU70396.1KEGG: eta:ETA_27250 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; histidine kinase HAMP region domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein. (908 aa)
parEDNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (631 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (613 aa)
ADU70992.1Integral membrane sensor signal transduction histidine kinase; KEGG: eta:ETA_32180 osmolarity sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein. (452 aa)
ADU71070.1KEGG: eta:ETA_33620 sensor protein KdpD; PFAM: Osmosensitive K channel His kinase sensor; UspA domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (891 aa)
ADU71172.1Integral membrane sensor signal transduction histidine kinase; KEGG: eta:ETA_00940 two-component sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein. (458 aa)
ADU71232.1Signal transduction histidine kinase, nitrogen specific, NtrB; KEGG: eta:ETA_00290 nitrogen regulation protein NR(II); PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein. (349 aa)
ADU71254.1KEGG: pwa:Pecwa_4531 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (443 aa)
Your Current Organism:
Pantoea sp. At9b
NCBI taxonomy Id: 592316
Other names: P. sp. At-9b, Pantoea sp. At-9b
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.