(45 nodes) Valine, leucine and isoleucine degradation network (Pseudomonas peli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SCW30845.1	Enoyl-CoA hydratase/carnithine racemase. (263 aa)
	SCW29819.1	Short chain enoyl-CoA hydratase. (714 aa)
	SCW29738.1	enoyl-CoA hydratase. (229 aa)
	SCW88468.1	acyl-CoA dehydrogenase. (382 aa)
	SCW87006.1	acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
	SCW85249.1	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa)
	SCW82141.1	Beta-alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
	SCW82130.1	Methylmalonate-semialdehyde dehydrogenase [acylating]. (498 aa)
	SCW81592.1	Short chain enoyl-CoA hydratase. (257 aa)
	SCW78171.1	Hypothetical protein. (113 aa)
	SCW71831.1	acyl-CoA dehydrogenase. (415 aa)
	SCW71107.1	hydroxymethylglutaryl-CoA lyase. (300 aa)
	SCW71087.1	methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (266 aa)
	SCW71075.1	3-methylcrotonyl-CoA carboxylase beta subunit. (535 aa)
	SCW71059.1	isovaleryl-CoA dehydrogenase. (387 aa)
	SCW71016.1	acyl-CoA dehydrogenase. (409 aa)
	SCW68692.1	acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
	SCW67978.1	Dihydrolipoamide dehydrogenase. (478 aa)
	SCW67846.1	3-hydroxyisobutyrate dehydrogenase. (289 aa)
	SCW66687.1	Dihydrolipoamide dehydrogenase. (466 aa)
	SCW61669.1	Methylmalonate-semialdehyde dehydrogenase [acylating]. (498 aa)
	SCW61660.1	Hypothetical protein. (388 aa)
	SCW61648.1	Short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (272 aa)
	SCW61636.1	Enoyl-CoA hydratase/carnithine racemase. (367 aa)
	SCW61626.1	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (294 aa)
	SCW61266.1	Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (348 aa)
	SCW60513.1	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
	SCW50380.1	Hypothetical protein. (121 aa)
	SCW49819.1	Hypothetical protein. (113 aa)
	SCW48776.1	Coniferyl-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (480 aa)
	ilvE	Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (307 aa)
	SCW46020.1	acyl-CoA dehydrogenase. (402 aa)
	SCW44560.1	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
	SCW42748.1	Putative acyl-CoA dehydrogenase. (550 aa)
	SCW42380.1	acyl-CoA dehydrogenase. (378 aa)
	SCW41353.1	Hypothetical protein. (295 aa)
	SCW41271.1	acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
	SCW40583.1	Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (339 aa)
	SCW34634.1	3-hydroxyisobutyrate dehydrogenase. (301 aa)
	SCW33541.1	Hypothetical protein. (99 aa)
	fadB	Short chain enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (715 aa)
	fadA	3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (391 aa)
	SCW31124.1	isohexenylglutaconyl-CoA hydratase. (266 aa)
	SCW31105.1	citronellyl-CoA dehydrogenase. (386 aa)
	SCW31086.1	geranyl-CoA carboxylase beta subunit. (538 aa)

Your Current Organism:

Pseudomonas peli

NCBI taxonomy Id: 592361
Other names: DSM 17833, LMG 23201, LMG:23201, P. peli, Pseudomonas peli Vanparys et al. 2006, Pseudomonas sp. R-20815, strain R-20805

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SCW29738.1	SCW29819.1	SAMN05216370_0226	SAMN05216370_0235	enoyl-CoA hydratase.	Short chain enoyl-CoA hydratase.	0.747
SCW29738.1	SCW30845.1	SAMN05216370_0226	SAMN05216370_0320	enoyl-CoA hydratase.	Enoyl-CoA hydratase/carnithine racemase.	0.718
SCW29738.1	SCW31086.1	SAMN05216370_0226	SAMN05216370_0337	enoyl-CoA hydratase.	geranyl-CoA carboxylase beta subunit.	0.625
SCW29738.1	SCW31105.1	SAMN05216370_0226	SAMN05216370_0338	enoyl-CoA hydratase.	citronellyl-CoA dehydrogenase.	0.741
SCW29738.1	SCW31124.1	SAMN05216370_0226	SAMN05216370_0339	enoyl-CoA hydratase.	isohexenylglutaconyl-CoA hydratase.	0.509
SCW29738.1	SCW34634.1	SAMN05216370_0226	SAMN05216370_0588	enoyl-CoA hydratase.	3-hydroxyisobutyrate dehydrogenase.	0.428
SCW29738.1	SCW41271.1	SAMN05216370_0226	SAMN05216370_1038	enoyl-CoA hydratase.	acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.875
SCW29738.1	SCW41353.1	SAMN05216370_0226	SAMN05216370_1044	enoyl-CoA hydratase.	Hypothetical protein.	0.852
SCW29738.1	SCW42380.1	SAMN05216370_0226	SAMN05216370_1126	enoyl-CoA hydratase.	acyl-CoA dehydrogenase.	0.729
SCW29738.1	SCW42748.1	SAMN05216370_0226	SAMN05216370_1153	enoyl-CoA hydratase.	Putative acyl-CoA dehydrogenase.	0.824
SCW29738.1	SCW44560.1	SAMN05216370_0226	SAMN05216370_1289	enoyl-CoA hydratase.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.874
SCW29738.1	SCW46020.1	SAMN05216370_0226	SAMN05216370_1390	enoyl-CoA hydratase.	acyl-CoA dehydrogenase.	0.753
SCW29738.1	SCW60513.1	SAMN05216370_0226	SAMN05216370_2082	enoyl-CoA hydratase.	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.729
SCW29738.1	SCW61626.1	SAMN05216370_0226	SAMN05216370_2179	enoyl-CoA hydratase.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.565
SCW29738.1	SCW61636.1	SAMN05216370_0226	SAMN05216370_2180	enoyl-CoA hydratase.	Enoyl-CoA hydratase/carnithine racemase.	0.662
SCW29738.1	SCW61648.1	SAMN05216370_0226	SAMN05216370_2181	enoyl-CoA hydratase.	Short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.611
SCW29738.1	SCW61660.1	SAMN05216370_0226	SAMN05216370_2182	enoyl-CoA hydratase.	Hypothetical protein.	0.687
SCW29738.1	SCW67846.1	SAMN05216370_0226	SAMN05216370_2736	enoyl-CoA hydratase.	3-hydroxyisobutyrate dehydrogenase.	0.428
SCW29738.1	SCW68692.1	SAMN05216370_0226	SAMN05216370_2810	enoyl-CoA hydratase.	acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.896
SCW29738.1	SCW71016.1	SAMN05216370_0226	SAMN05216370_3027	enoyl-CoA hydratase.	acyl-CoA dehydrogenase.	0.786