STRINGSTRING
SCW41126.1 SCW41126.1 SCW41048.1 SCW41048.1 ackA ackA SCW40556.1 SCW40556.1 leuA leuA ppc ppc accA accA SCW31185.1 SCW31185.1 mqo mqo SCW87006.1 SCW87006.1 acsA-2 acsA-2 SCW76177.1 SCW76177.1 glcB glcB SCW79525.1 SCW79525.1 mqo-2 mqo-2 SCW81582.1 SCW81582.1 SCW81619.1 SCW81619.1 SCW83399.1 SCW83399.1 SCW83588.1 SCW83588.1 gloB gloB SCW51928.1 SCW51928.1 SCW51826.1 SCW51826.1 SCW51819.1 SCW51819.1 pckA pckA SCW48776.1 SCW48776.1 SCW47292.1 SCW47292.1 SCW46419.1 SCW46419.1 SCW46405.1 SCW46405.1 SCW75870.1 SCW75870.1 SCW75420.1 SCW75420.1 SCW71274.1 SCW71274.1 SCW71115.1 SCW71115.1 SCW70659.1 SCW70659.1 SCW69200.1 SCW69200.1 acsA acsA SCW68995.1 SCW68995.1 fumC fumC SCW67978.1 SCW67978.1 SCW67374.1 SCW67374.1 SCW66687.1 SCW66687.1 SCW65911.1 SCW65911.1 SCW64854.1 SCW64854.1 SCW63925.1 SCW63925.1 accD accD SCW61025.1 SCW61025.1 SCW61013.1 SCW61013.1 oadG oadG SCW85780.1 SCW85780.1 SCW44718.1 SCW44718.1 SCW44704.1 SCW44704.1 SCW44560.1 SCW44560.1 SCW41763.1 SCW41763.1 SCW41271.1 SCW41271.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCW41126.1Glyoxylase, beta-lactamase superfamily II. (215 aa)
SCW41048.1Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (697 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa)
SCW40556.1Glyoxylase, beta-lactamase superfamily II. (332 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (556 aa)
ppcPhosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (878 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (316 aa)
SCW31185.1Hypothetical protein. (124 aa)
mqoMalate dehydrogenase (quinone). (531 aa)
SCW87006.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
acsA-2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa)
SCW76177.1Hypothetical protein. (115 aa)
glcBMalate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (725 aa)
SCW79525.1Propionate CoA-transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family. (519 aa)
mqo-2Malate dehydrogenase (quinone). (500 aa)
SCW81582.1Pyruvate kinase; Belongs to the pyruvate kinase family. (483 aa)
SCW81619.1Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa)
SCW83399.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa)
SCW83588.1Glyoxylase, beta-lactamase superfamily II. (290 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (268 aa)
SCW51928.1Predicted lactoylglutathione lyase. (122 aa)
SCW51826.1Biotin carboxylase /acetyl-CoA carboxylase carboxyltransferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (472 aa)
SCW51819.1Pyruvate carboxylase subunit B. (602 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (513 aa)
SCW48776.1Coniferyl-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (480 aa)
SCW47292.1Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). (422 aa)
SCW46419.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (555 aa)
SCW46405.1Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (881 aa)
SCW75870.1Hypothetical protein. (141 aa)
SCW75420.1Putative intracellular protease/amidase. (227 aa)
SCW71274.1High-affinity iron transporter. (281 aa)
SCW71115.1acetoacetyl-CoA synthetase. (651 aa)
SCW70659.1Catechol 2,3-dioxygenase. (140 aa)
SCW69200.1Pyruvate kinase; Belongs to the pyruvate kinase family. (471 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (677 aa)
SCW68995.1PhnB protein. (139 aa)
fumCFumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
SCW67978.1Dihydrolipoamide dehydrogenase. (478 aa)
SCW67374.1Phosphoglycerate dehydrogenase. (318 aa)
SCW66687.1Dihydrolipoamide dehydrogenase. (466 aa)
SCW65911.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa)
SCW64854.1Acylphosphatase. (91 aa)
SCW63925.1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (130 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (294 aa)
SCW61025.1Oxaloacetate decarboxylase, beta subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family. (378 aa)
SCW61013.1Oxaloacetate decarboxylase, alpha subunit. (591 aa)
oadGOxaloacetate decarboxylase, gamma subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (83 aa)
SCW85780.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa)
SCW44718.1Biotin carboxylase /acetyl-CoA carboxylase carboxyltransferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
SCW44704.1acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (153 aa)
SCW44560.13-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
SCW41763.1UPF0716 protein FxsA. (149 aa)
SCW41271.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
Your Current Organism:
Pseudomonas peli
NCBI taxonomy Id: 592361
Other names: DSM 17833, LMG 23201, LMG:23201, P. peli, Pseudomonas peli Vanparys et al. 2006, Pseudomonas sp. R-20815, strain R-20805
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