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aeF1-B aeF1-B TGAM_0201 TGAM_0201 rpl11P rpl11P rpl1P rpl1P rpl10E-1 rpl10E-1 rpl12A rpl12A rps24E rps24E rps8E rps8E rpl37AE rpl37AE eIF2A eIF2A rps17E rps17E map map rps3AE rps3AE rps15P rps15P rpl21E rpl21E proS proS tuf tuf rps10P rps10P rps19E rps19E eIF2G eIF2G rpl35AE rpl35AE eIF1A eIF1A rpl44E rpl44E rplXA rplXA eif6 eif6 rpl31E rpl31E gltX gltX rpl15E rpl15E infB infB rpl24E rpl24E rps28E rps28E rps12P rps12P rpl30E rpl30E rpl40E rpl40E rps2P rps2P rpl13P rpl13P rpl18E rpl18E rps13P rps13P rsmC rsmC rpl14E rpl14E rpl34E rpl34E rpl15P rpl15P rpl30P rpl30P rpl18P rpl18P rpl19E rpl19E rpl32E rpl32E rpl6P rpl6P rps8P rps8P rps14P rps14P rpl5P rpl5P rps4E rps4E rpl24P rpl24P rpl14P rpl14P rps17P rps17P suI1 suI1 rpl29P rpl29P rps3P rps3P rpl22P rpl22P rps19P rps19P rpl2P rpl2P rpl23P rpl23P rpl3P rpl3P rpl10E-2 rpl10E-2 eif2b eif2b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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aeF1-BTranslation elongation factor aEF-1, subunit beta (aeF1-B); Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (91 aa)
TGAM_0201GTP-binding protein, HSR1-related GTPase; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (339 aa)
rpl11PLSU ribosomal protein L11P (rpl11P); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (165 aa)
rpl1PLSU ribosomal protein L1P (rpl1P); Binds directly to 23S rRNA. Probably involved in E site tRNA release. (216 aa)
rpl10E-1LSU ribosomal protein L10E (rpl10E); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (340 aa)
rpl12ALSU ribosomal protein L12A (rpl12A); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (106 aa)
rps24ESSU ribosomal protein S24E (rps24E); Belongs to the eukaryotic ribosomal protein eS24 family. (98 aa)
rps8ESSU ribosomal protein S8E (rps8E). (130 aa)
rpl37AELSU ribosomal protein L37AE (rpl37AE). (86 aa)
eIF2ATranslation initiation factor 2 alpha subunit (eIF2A); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. (273 aa)
rps17ESSU ribosomal protein S17E (rps17E); Belongs to the eukaryotic ribosomal protein eS17 family. (67 aa)
mapMethionine aminopeptidase (map); Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. (295 aa)
rps3AESSU ribosomal protein S3AE (rps3AE); Belongs to the eukaryotic ribosomal protein eS1 family. (200 aa)
rps15PSSU ribosomal protein S15P (rps15P). (151 aa)
rpl21ELSU ribosomal protein L21E (rpl21E); Belongs to the eukaryotic ribosomal protein eL21 family. (98 aa)
proSProlyl-tRNA synthetase (proS); Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (483 aa)
tufElongation factor 1-alpha (EF-1-alpha) (Elongation factor Tu) (EF-Tu) (tuf); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (428 aa)
rps10PSSU ribosomal protein S10P (rps10P); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rps19ESSU ribosomal protein S19E (rps19E); May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (150 aa)
eIF2GTranslation initiation factor eIF-2, subunit gamma (eIF2G) (eIF2G); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (411 aa)
rpl35AELSU ribosomal protein L35AE (rpl35AE); Belongs to the eukaryotic ribosomal protein eL33 family. (87 aa)
eIF1AeIF1A translation initiation factor eIF-1A (eIF1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (172 aa)
rpl44ELSU ribosomal protein L44E (rpl44E); Binds to the 23S rRNA. (94 aa)
rplXALSU ribosomal protein LXA (rplXA). (77 aa)
eif6Translation initiation factor 6 (eif6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (228 aa)
rpl31ELSU ribosomal protein L31E (rpl31E); Belongs to the eukaryotic ribosomal protein eL31 family. (90 aa)
gltXGlutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (571 aa)
rpl15ELSU ribosomal protein L15E (rpl15E); Belongs to the eukaryotic ribosomal protein eL15 family. (194 aa)
infBTranslation initiation factor IF-2 (infB); Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (600 aa)
rpl24ELSU ribosomal protein L24E (rpl24E); Binds to the 23S rRNA. (68 aa)
rps28ESSU ribosomal protein S28E (rps28E); Belongs to the eukaryotic ribosomal protein eS28 family. (70 aa)
rps12PSSU ribosomal protein S12P (rps12P); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa)
rpl30ELSU ribosomal protein L30E (rpl30E); Belongs to the eukaryotic ribosomal protein eL30 family. (102 aa)
rpl40ELSU ribosomal protein L40E (rpl40E); Belongs to the eukaryotic ribosomal protein eL40 family. (51 aa)
rps2PSSU ribosomal protein S2P (rps2P); Belongs to the universal ribosomal protein uS2 family. (201 aa)
rpl13PLSU ribosomal protein L13P (rpl13P); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa)
rpl18ELSU ribosomal protein L18E (rpl18E); Belongs to the eukaryotic ribosomal protein eL18 family. (121 aa)
rps13PSSU ribosomal protein S13P (rps13P); Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (149 aa)
rsmCRibosomal RNA small subunit methyltransferase C (rsmC). (195 aa)
rpl14ELSU ribosomal protein L14E (rpl14E); Belongs to the eukaryotic ribosomal protein eL14 family. (83 aa)
rpl34ELSU ribosomal protein L34E (rpl34E); Belongs to the eukaryotic ribosomal protein eL34 family. (89 aa)
rpl15PLSU ribosomal protein L15P (rpl15P); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (148 aa)
rpl30PLSU ribosomal protein L30P (rpl30P). (155 aa)
rpl18PLSU ribosomal protein L18P (rpl18P); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (201 aa)
rpl19ELSU ribosomal protein L19E (rpl19E); Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (150 aa)
rpl32ELSU ribosomal protein L32E (rpl32E); Belongs to the eukaryotic ribosomal protein eL32 family. (127 aa)
rpl6PLSU ribosomal protein L6P (rpl6P); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (184 aa)
rps8PSSU ribosomal protein S8P (rps8P); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rps14PSSU ribosomal protein S14P (rps14P); Binds 16S rRNA, required for the assembly of 30S particles. (56 aa)
rpl5PLSU ribosomal protein L5P (rpl5P); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (183 aa)
rps4ESSU ribosomal protein S4E (rps4E); Belongs to the eukaryotic ribosomal protein eS4 family. (243 aa)
rpl24PLSU ribosomal protein L24P (rpl24P); Located at the polypeptide exit tunnel on the outside of the subunit. (121 aa)
rpl14PLSU ribosomal protein L14P (rpl14P); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (141 aa)
rps17PSSU ribosomal protein S17P (rps17P); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (114 aa)
suI1Protein translation factor SUI1-like protein (SUI1); Belongs to the SUI1 family. (98 aa)
rpl29PLSU ribosomal protein L29P (rpl29P); Belongs to the universal ribosomal protein uL29 family. (66 aa)
rps3PSSU ribosomal protein S3P (rps3P); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (209 aa)
rpl22PLSU ribosomal protein L22P (rpl22P); The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (156 aa)
rps19PSSU ribosomal protein S19P (rps19P); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (133 aa)
rpl2PLSU ribosomal protein L2P (rpl2P); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (239 aa)
rpl23PLSU ribosomal protein L23P (rpl23P); Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa)
rpl3PLSU ribosomal protein L3P (rpl3P); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (346 aa)
rpl10E-2LSU ribosomal protein L10 (rpl10E); Belongs to the universal ribosomal protein uL16 family. (182 aa)
eif2bTranslation initiation factor 2 beta subunit (eif2b); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (142 aa)
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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