STRINGSTRING
trpS trpS TGAM_0537 TGAM_0537 ileS ileS valS valS TGAM_0691 TGAM_0691 argS argS asnS-1 asnS-1 thrS thrS pheS pheS pheT pheT metG metG cysS cysS glyS glyS leuS leuS serS serS asnS-2 asnS-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
trpSTryptophanyl-tRNA synthetase (trpS); Catalyzes the attachment of tryptophan to tRNA(Trp). (384 aa)
TGAM_0537Conserved hypothetical protein, predicted polysaccharide hydrolase or cysteinyl-tRNA synthetase; Controversial assignement (see PMID:11333988 and 14679218); 1 probable transmembrane helix predicted by modhmm. (397 aa)
ileSIsoleucyl-tRNA synthetase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1066 aa)
valSValyl-tRNA synthetase (valS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (888 aa)
TGAM_0691GTPase, MMR-HSR1 family; Belongs to G-protein superfamily. Contains 1 TGS domain. (397 aa)
argSArginyl-tRNA synthetase (argS); Belongs to the class-I aminoacyl-tRNA synthetase family. (640 aa)
asnS-1Asparaginyl-tRNA synthetase (asnS); Belongs to the class-II aminoacyl-tRNA synthetase family. (430 aa)
thrSThreonyl-tRNA synthetase (thrS); Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr); Belongs to the class-II aminoacyl-tRNA synthetase family. (626 aa)
pheSPhenylalanyl-tRNA synthetase, alpha subunit (pheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (499 aa)
pheTPhenylalanyl-tRNA synthetase, beta subunit (pheT_arch). (568 aa)
metGMethionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (739 aa)
cysSCysteinyl-tRNA synthetase (cysS). (476 aa)
glySGlycyl-tRNA synthetase (glyS); Catalyzes the attachment of glycine to tRNA(Gly). (570 aa)
leuSLeucyl-tRNA synthetase (leuS); Belongs to the class-I aminoacyl-tRNA synthetase family. (968 aa)
serSSeryl-tRNA synthetase (serS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (455 aa)
asnS-2Asparaginyl-tRNA synthetase related protein (asnS). (300 aa)
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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