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| | aeF1-B | Translation elongation factor aEF-1, subunit beta (aeF1-B); Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (91 aa) |
| | TGAM_0166 | Nucleic acid-binding protein, containing OB-fold domain. (64 aa) |
| | TGAM_0201 | GTP-binding protein, HSR1-related GTPase; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (339 aa) |
| | trpS | Tryptophanyl-tRNA synthetase (trpS); Catalyzes the attachment of tryptophan to tRNA(Trp). (384 aa) |
| | tfe | Transcription factor TFIIE subunit alpha-like protein (tfe); Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and desta [...] (221 aa) |
| | TGAM_0279 | Ribosome subunit biogenesis protein, putative; Belongs to UPF0113 family. (167 aa) |
| | nac | Nascent polypeptide-associated complex protein (nac); Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. (112 aa) |
| | tbp-1 | TATA box-binding protein, transcription initiation factor TFIID (tbp); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (192 aa) |
| | flpA | Fibrillarin pre-rRNA splicing protein (flpA); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (226 aa) |
| | TGAM_0464 | pre-mRNA splicing, snoRNA binding protein, NOP5/NOP56 related. (422 aa) |
| | gar1 | Gar1-like small nucleolar rnp, putative (gar1). (99 aa) |
| | tfb-1 | Transcription initiation factor TFIIB (tfb); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (303 aa) |
| | secE | Protein translocase SEC61 complex gamma subunit, archaeal/eukaryotic type (secE); Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (64 aa) |
| | rpl11P | LSU ribosomal protein L11P (rpl11P); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (165 aa) |
| | rpl1P | LSU ribosomal protein L1P (rpl1P); Binds directly to 23S rRNA. Probably involved in E site tRNA release. (216 aa) |
| | rpl10E-1 | LSU ribosomal protein L10E (rpl10E); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (340 aa) |
| | rpl12A | LSU ribosomal protein L12A (rpl12A); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (106 aa) |
| | rpoE1 | DNA-directed RNA polymerase subunit E' (rpoE1). (186 aa) |
| | rps24E | SSU ribosomal protein S24E (rps24E); Belongs to the eukaryotic ribosomal protein eS24 family. (98 aa) |
| | rps27AE | SSU ribosomal protein S27AE (rps27AE); Belongs to the eukaryotic ribosomal protein eS31 family. (56 aa) |
| | TGAM_0537 | Conserved hypothetical protein, predicted polysaccharide hydrolase or cysteinyl-tRNA synthetase; Controversial assignement (see PMID:11333988 and 14679218); 1 probable transmembrane helix predicted by modhmm. (397 aa) |
| | ileS | Isoleucyl-tRNA synthetase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1066 aa) |
| | TGAM_0645 | GTPase, NOG1/MMR-HSR1 family; Belongs to G-protein superfamily. (357 aa) |
| | rps8E | SSU ribosomal protein S8E (rps8E). (130 aa) |
| | valS | Valyl-tRNA synthetase (valS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (888 aa) |
| | TGAM_0691 | GTPase, MMR-HSR1 family; Belongs to G-protein superfamily. Contains 1 TGS domain. (397 aa) |
| | eRF1 | Peptide chain release factor eRF/aRF, subunit 1 (eRF1/prf1); Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (418 aa) |
| | argS | Arginyl-tRNA synthetase (argS); Belongs to the class-I aminoacyl-tRNA synthetase family. (640 aa) |
| | asnS-1 | Asparaginyl-tRNA synthetase (asnS); Belongs to the class-II aminoacyl-tRNA synthetase family. (430 aa) |
| | rad3 | DNA repair helicase, ERCC2/XPD/rad3/TFIIH helicase beta subunit-like protein (rad3). (640 aa) |
| | rpoP | DNA-directed RNA polymerase subunit P (rpoP); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. (91 aa) |
| | rpl37AE | LSU ribosomal protein L37AE (rpl37AE). (86 aa) |
| | eIF2A | Translation initiation factor 2 alpha subunit (eIF2A); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. (273 aa) |
| | nop10 | Nucleolar RNA-binding protein, Nop10p family; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (59 aa) |
| | tbp-2 | TATA box-binding protein, transcription initiation factor TFIID (tbp); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (182 aa) |
| | TGAM_0852 | Nonsense-mediated mRNA decay protein, NMD3-like protein. (392 aa) |
| | rps17E | SSU ribosomal protein S17E (rps17E); Belongs to the eukaryotic ribosomal protein eS17 family. (67 aa) |
| | map | Methionine aminopeptidase (map); Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. (295 aa) |
| | rps3AE | SSU ribosomal protein S3AE (rps3AE); Belongs to the eukaryotic ribosomal protein eS1 family. (200 aa) |
| | rps15P | SSU ribosomal protein S15P (rps15P). (151 aa) |
| | hel308 | Ski2-type helicase, putative; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (720 aa) |
| | srp19 | Signal recognition particle, subunit SRP19 (srp19); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. (109 aa) |
| | rpoF | DNA-directed RNA polymerase subunit F (rpoF). (122 aa) |
| | rpl21E | LSU ribosomal protein L21E (rpl21E); Belongs to the eukaryotic ribosomal protein eL21 family. (98 aa) |
| | adk | Adenylate kinase (adk); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (224 aa) |
| | rpl41e | LSU ribosomal protein L41E (rpl41e). (40 aa) |
| | TGAM_0970 | WD40-domain containing protein; 1 probable transmembrane helix predicted by modhmm. (3037 aa) |
| | rpoL | DNA-directed RNA polymerase subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (95 aa) |
| | csl4 | RNA-binding protein, containing S1 RNA binding domain; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (195 aa) |
| | thrS | Threonyl-tRNA synthetase (thrS); Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr); Belongs to the class-II aminoacyl-tRNA synthetase family. (626 aa) |
| | dhys | Deoxyhypusine synthase (dhys); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. (336 aa) |
| | eIF-5A | Translation initiation factor eIF-5A (hypusine containing) (eIF-5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (136 aa) |
| | tfs | Transcription elongation factor S (TFS_arch); Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (110 aa) |
| | proS | Prolyl-tRNA synthetase (proS); Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (483 aa) |
| | tuf | Elongation factor 1-alpha (EF-1-alpha) (Elongation factor Tu) (EF-Tu) (tuf); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (428 aa) |
| | rps10P | SSU ribosomal protein S10P (rps10P); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | TGAM_1139 | Predicted ATPase, RNase L inhibitor-like protein. (590 aa) |
| | pheS | Phenylalanyl-tRNA synthetase, alpha subunit (pheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (499 aa) |
| | pheT | Phenylalanyl-tRNA synthetase, beta subunit (pheT_arch). (568 aa) |
| | TGAM_1186 | Nucleotide binding protein, putative, containing PIN domain. (167 aa) |
| | TGAM_1193 | ATPase, putative, PP-loop superfamily. (206 aa) |
| | rps19E | SSU ribosomal protein S19E (rps19E); May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (150 aa) |
| | TGAM_1196 | DNA-binding protein, TFAR19-related; Putative DNA double-stranded binding protein; Belongs to the PDCD5 family. (112 aa) |
| | tfb-2 | Transcription initiation factor TFIIB (tfb); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (300 aa) |
| | eIF2G | Translation initiation factor eIF-2, subunit gamma (eIF2G) (eIF2G); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (411 aa) |
| | tmcA | Predicted P-loop ATPase fused to an acetyltransferase (GNAT) family; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (811 aa) |
| | rpl35AE | LSU ribosomal protein L35AE (rpl35AE); Belongs to the eukaryotic ribosomal protein eL33 family. (87 aa) |
| | TGAM_1396 | SAM-dependent tRNA/rRNA cytosine-C5 methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (309 aa) |
| | fusA | Translation elongation factor EF-2 (fusA); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. E [...] (732 aa) |
| | TGAM_1410 | Serine/threonine protein kinase, RIO-like protein. (310 aa) |
| | nep1 | Ribosome biogenesis protein NEP1-like protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (216 aa) |
| | eIF1A | eIF1A translation initiation factor eIF-1A (eIF1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (172 aa) |
| | rio1 | Protein serine/threonine kinase, RIO1 family (rio1). (258 aa) |
| | TGAM_1424 | RNA-binding protein, containing KH domain. (234 aa) |
| | TGAM_1432 | GTP-binding protein; Contains Ras GTPase and GTP1/OBG family signatures. (188 aa) |
| | TGAM_1454 | SAM-dependent tRNA/rRNA cytosine-C5 methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (451 aa) |
| | rps27E | SSU ribosomal protein S27E (rps27E). (65 aa) |
| | rpl44E | LSU ribosomal protein L44E (rpl44E); Binds to the 23S rRNA. (94 aa) |
| | TGAM_1498 | Brix-domain ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome. (211 aa) |
| | metG | Methionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (739 aa) |
| | cysS | Cysteinyl-tRNA synthetase (cysS). (476 aa) |
| | rps6E | SSU ribosomal protein S6E (rps6E); Belongs to the eukaryotic ribosomal protein eS6 family. (125 aa) |
| | ftsY | GTP-binding signal recognition particle receptor (SRP alpha, SRP54) (FtsY/SRP54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (328 aa) |
| | TGAM_1658 | DNA repair helicase, XPB-rad25 -like protein. (462 aa) |
| | rplXA | LSU ribosomal protein LXA (rplXA). (77 aa) |
| | eif6 | Translation initiation factor 6 (eif6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (228 aa) |
| | rpl31E | LSU ribosomal protein L31E (rpl31E); Belongs to the eukaryotic ribosomal protein eL31 family. (90 aa) |
| | rpl39E | LSU ribosomal protein L39E (rpl39E); Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa) |
| | TGAM_1687 | mRNA 3-end processing factor, putative; Contains 1 Metallo-hydrolase/oxidoreductase fold (SSF56281). (285 aa) |
| | glyS | Glycyl-tRNA synthetase (glyS); Catalyzes the attachment of glycine to tRNA(Gly). (570 aa) |
| | TGAM_1738 | Small nuclear ribonucleoprotein (snRNP)-like protein, Sm-like protein; Belongs to the snRNP Sm proteins family. (76 aa) |
| | rpl37E | LSU ribosomal protein L37E (rpl37E); Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (63 aa) |
| | gltX | Glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (571 aa) |
| | rpl15E | LSU ribosomal protein L15E (rpl15E); Belongs to the eukaryotic ribosomal protein eL15 family. (194 aa) |
| | leuS | Leucyl-tRNA synthetase (leuS); Belongs to the class-I aminoacyl-tRNA synthetase family. (968 aa) |
| | infB | Translation initiation factor IF-2 (infB); Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (600 aa) |
| | ndk | Nucleoside diphosphate kinase (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (177 aa) |
| | rpl24E | LSU ribosomal protein L24E (rpl24E); Binds to the 23S rRNA. (68 aa) |
| | rps28E | SSU ribosomal protein S28E (rps28E); Belongs to the eukaryotic ribosomal protein eS28 family. (70 aa) |
| | rpl7AE | LSU ribosomal protein L7AE (rpl7AE); Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (123 aa) |
| | deaD | ATP-dependent RNA helicase, DEAD-family (deaD); Belongs to the DEAD box helicase family. (403 aa) |
| | rps7P | SSU ribosomal protein S7P (rps7P); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (215 aa) |
| | rps12P | SSU ribosomal protein S12P (rps12P); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa) |
| | nusA-2 | Transcription termination-antitermination factor, NusA-like protein (nusA); Participates in transcription termination. Belongs to the NusA family. (145 aa) |
| | rpl30E | LSU ribosomal protein L30E (rpl30E); Belongs to the eukaryotic ribosomal protein eL30 family. (102 aa) |
| | rpoA2 | DNA-directed RNA polymerase subunit A' (rpoA2); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (391 aa) |
| | rpoA1 | DNA-directed RNA polymerase subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (905 aa) |
| | rpoB | DNA-directed RNA polymerase subunit B (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1122 aa) |
| | rpoH | DNA-directed RNA polymerase subunit H (rpoH); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (82 aa) |
| | serS | Seryl-tRNA synthetase (serS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (455 aa) |
| | srp54 | Signal recognition particle, subunit SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (448 aa) |
| | TGAM_1955 | Metallophosphoesterase, MJ0912 type. (253 aa) |
| | rpl40E | LSU ribosomal protein L40E (rpl40E); Belongs to the eukaryotic ribosomal protein eL40 family. (51 aa) |
| | rps2P | SSU ribosomal protein S2P (rps2P); Belongs to the universal ribosomal protein uS2 family. (201 aa) |
| | rpoK | DNA-directed RNA polymerase subunit K (rpoK); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (57 aa) |
| | rpoN | DNA-directed RNA polymerase subunit N (rpoN); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (70 aa) |
| | rps9P | SSU ribosomal protein S9P (rps9P); Belongs to the universal ribosomal protein uS9 family. (135 aa) |
| | rpl13P | LSU ribosomal protein L13P (rpl13P); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa) |
| | rpl18E | LSU ribosomal protein L18E (rpl18E); Belongs to the eukaryotic ribosomal protein eL18 family. (121 aa) |
| | rpoD | DNA-directed RNA polymerase subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. (260 aa) |
| | rps11P | SSU ribosomal protein S11P (rps11P); Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (138 aa) |
| | rps4P | SSU ribosomal protein S4P (rps4P); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (180 aa) |
| | rps13P | SSU ribosomal protein S13P (rps13P); Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (149 aa) |
| | rsmC | Ribosomal RNA small subunit methyltransferase C (rsmC). (195 aa) |
| | truB | Centromere binding protein CBF5/pseudouridine synthase truB-like protein (truB); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (334 aa) |
| | rpl14E | LSU ribosomal protein L14E (rpl14E); Belongs to the eukaryotic ribosomal protein eL14 family. (83 aa) |
| | cmk | Cytidylate kinase, putative (cmk); 1 probable transmembrane helix predicted by modhmm. (197 aa) |
| | rpl34E | LSU ribosomal protein L34E (rpl34E); Belongs to the eukaryotic ribosomal protein eL34 family. (89 aa) |
| | secY | Preprotein translocase secY subunit (secY); The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (461 aa) |
| | rpl15P | LSU ribosomal protein L15P (rpl15P); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (148 aa) |
| | rpl30P | LSU ribosomal protein L30P (rpl30P). (155 aa) |
| | rps5P | SSU ribosomal protein S5P (rps5P); With S4 and S12 plays an important role in translational accuracy. (234 aa) |
| | rpl18P | LSU ribosomal protein L18P (rpl18P); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (201 aa) |
| | rpl19E | LSU ribosomal protein L19E (rpl19E); Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (150 aa) |
| | rpl32E | LSU ribosomal protein L32E (rpl32E); Belongs to the eukaryotic ribosomal protein eL32 family. (127 aa) |
| | rpl6P | LSU ribosomal protein L6P (rpl6P); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (184 aa) |
| | rps8P | SSU ribosomal protein S8P (rps8P); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rps14P | SSU ribosomal protein S14P (rps14P); Binds 16S rRNA, required for the assembly of 30S particles. (56 aa) |
| | rpl5P | LSU ribosomal protein L5P (rpl5P); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (183 aa) |
| | rps4E | SSU ribosomal protein S4E (rps4E); Belongs to the eukaryotic ribosomal protein eS4 family. (243 aa) |
| | rpl24P | LSU ribosomal protein L24P (rpl24P); Located at the polypeptide exit tunnel on the outside of the subunit. (121 aa) |
| | rpl14P | LSU ribosomal protein L14P (rpl14P); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (141 aa) |
| | rps17P | SSU ribosomal protein S17P (rps17P); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (114 aa) |
| | suI1 | Protein translation factor SUI1-like protein (SUI1); Belongs to the SUI1 family. (98 aa) |
| | rpl29P | LSU ribosomal protein L29P (rpl29P); Belongs to the universal ribosomal protein uL29 family. (66 aa) |
| | rps3P | SSU ribosomal protein S3P (rps3P); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (209 aa) |
| | rpl22P | LSU ribosomal protein L22P (rpl22P); The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (156 aa) |
| | rps19P | SSU ribosomal protein S19P (rps19P); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (133 aa) |
| | rpl2P | LSU ribosomal protein L2P (rpl2P); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (239 aa) |
| | rpl23P | LSU ribosomal protein L23P (rpl23P); Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa) |
| | rpl4P | LSU ribosomal protein L4P (rpl4P); One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (255 aa) |
| | rpl3P | LSU ribosomal protein L3P (rpl3P); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (346 aa) |
| | rpl10E-2 | LSU ribosomal protein L10 (rpl10E); Belongs to the universal ribosomal protein uL16 family. (182 aa) |
| | asnS-2 | Asparaginyl-tRNA synthetase related protein (asnS). (300 aa) |
| | rtcA | RNA 3'-terminal phosphate cyclase (rtcA); Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (344 aa) |
| | eif2b | Translation initiation factor 2 beta subunit (eif2b); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (142 aa) |
| | rrp42p | 3'-5' exoribonuclease, exosome complex exonuclease 2, Rrp42p-like protein (Rrp42p); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (273 aa) |
| | rrp41p | 3'-5' exoribonuclease, exosome complex exonuclease 1, Rrp41p-like protein (Rrp41p); Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. (249 aa) |
| | rrp4p | Exosome complex RNA-binding protein 1, Rrp4p-like protein (Rrp4p); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (254 aa) |
