STRINGSTRING
TGAM_0149 TGAM_0149 psmB-2 psmB-2 psmA psmA purR purR serS serS mre11 mre11 psmB-1 psmB-1 hsp20 hsp20 TGAM_1635 TGAM_1635 TGAM_1587 TGAM_1587 gde gde pan pan TGAM_1139 TGAM_1139 tuf tuf nadC-1 nadC-1 alaS alaS atpI atpI atpE atpE atpC atpC atpF atpF atpA atpA atpB atpB atpD atpD deoC deoC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGAM_0149Alanyl-tRNA synthetase-related protein (C-terminus). (405 aa)
psmB-2Peptidase T1A, 20S proteasome beta-subunit (psmB); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (200 aa)
psmAPeptidase T1A, 20S proteasome alpha-subunit (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (260 aa)
purRAdenine phosphoribosyltransferase, fused to N-terminal DNA binding domain (purR). (239 aa)
serSSeryl-tRNA synthetase (serS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (455 aa)
mre11DNA double-strand break repair protein mre11 (mre11); Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. (462 aa)
psmB-1Peptidase T1A, 20S proteasome beta-subunit (psmB); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (201 aa)
hsp20Small heat shock protein, Hsp20 type (Hsp20). (161 aa)
TGAM_1635Alanyl-tRNA synthetase related protein. (213 aa)
TGAM_1587Zinc-dependent metallopeptidase, putative; Contains zinc-binding region signature (PS00142). (387 aa)
gdeAmylo-alpha-1,6-glucosidase, putative archaeal type glycogen debranching enzyme (gde). (620 aa)
panATP-dependent 26S proteasome regulatory subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP bindin [...] (397 aa)
TGAM_1139Predicted ATPase, RNase L inhibitor-like protein. (590 aa)
tufElongation factor 1-alpha (EF-1-alpha) (Elongation factor Tu) (EF-Tu) (tuf); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (428 aa)
nadC-1Nicotinate-nucleotide pyrophosphorylase (nadC). (390 aa)
alaSAlanyl-tRNA synthetase (alaS); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (913 aa)
atpIArchaeal/vacuolar-type H+-ATPase subunit I (atpI); 7 probable transmembrane helices predicted by modhmm; Belongs to the V-ATPase 116 kDa subunit family. (668 aa)
atpEArchaeal/vacuolar-type H+-ATPase, subunit E (atpE); Produces ATP from ADP in the presence of a proton gradient across the membrane. (197 aa)
atpCArchaeal/vacuolar-type H+ ATPase, subunit C (atpC); Produces ATP from ADP in the presence of a proton gradient across the membrane. (366 aa)
atpFArchaeal/vacuolar-type H+-ATPase, subunit F (atpF); Produces ATP from ADP in the presence of a proton gradient across the membrane. (102 aa)
atpAArchaeal/vacuolar-type H+-ATPase subunit A (atpA); Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (585 aa)
atpBArchaeal/vacuolar-type H+-ATPase, subunit B (atpB); Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (463 aa)
atpDArchaeal/vacuolar-type H+-ATPase, subunit D (atpD); Produces ATP from ADP in the presence of a proton gradient across the membrane. (214 aa)
deoCDeoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA) (deoC); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (225 aa)
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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