28 items (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SF3B1	Splicing factor 3b subunit 1. (1304 aa)
	SF3A3	Splicing factor 3a subunit 3. (501 aa)
	SF3A1	Splicing factor 3a subunit 1. (793 aa)
	PHF5A	PHD finger protein 5A. (110 aa)
	SF3B6	Splicing factor 3b subunit 6. (125 aa)
	SNRPB2	Small nuclear ribonucleoprotein polypeptide B2. (225 aa)
	SF3B5	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
	SNRPD1	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (129 aa)
	SNRPD3	Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
	SF3B4	Splicing factor 3b subunit 4. (424 aa)
	G1PGR0_MYOLU	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
	SF3B2	Splicing factor 3b subunit 2. (896 aa)
	SNRNP70	Small nuclear ribonucleoprotein U1 subunit 70. (438 aa)
	DDX46	DEAD-box helicase 46. (1033 aa)
	SNRPA1	Small nuclear ribonucleoprotein polypeptide A. (250 aa)
	SF3B3	Splicing factor 3b subunit 3. (1216 aa)
	SNRPB	Small nuclear ribonucleoprotein-associated protein. (235 aa)
	G1Q0H1_MYOLU	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (79 aa)
	G1Q215_MYOLU	SF3A2 domain-containing protein. (360 aa)
	SNRPD2-2	Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
	G1Q817_MYOLU	Uncharacterized protein. (218 aa)
	G1Q9E9_MYOLU	Sm domain-containing protein. (203 aa)
	G1QD04_MYOLU	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
	G1QD57_MYOLU	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
	SNRPD2-5	Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (121 aa)
	LOC102434604	Sm domain-containing protein. (106 aa)
	G1QEQ4_MYOLU	Uncharacterized protein. (54 aa)
	LOC102437528	annotation not available (106 aa)

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX46	G1PGR0_MYOLU	ENSMLUP00000011486	ENSMLUP00000009835	DEAD-box helicase 46.	Splicing factor 3B subunit 5; Belongs to the SF3B5 family.	0.969
DDX46	G1Q0H1_MYOLU	ENSMLUP00000011486	ENSMLUP00000017203	DEAD-box helicase 46.	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development.	0.969
DDX46	G1Q215_MYOLU	ENSMLUP00000011486	ENSMLUP00000017748	DEAD-box helicase 46.	SF3A2 domain-containing protein.	0.982
DDX46	G1Q817_MYOLU	ENSMLUP00000011486	ENSMLUP00000019850	DEAD-box helicase 46.	Uncharacterized protein.	0.957
DDX46	G1Q9E9_MYOLU	ENSMLUP00000011486	ENSMLUP00000020332	DEAD-box helicase 46.	Sm domain-containing protein.	0.952
DDX46	G1QD04_MYOLU	ENSMLUP00000011486	ENSMLUP00000021587	DEAD-box helicase 46.	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.	0.945
DDX46	G1QD57_MYOLU	ENSMLUP00000011486	ENSMLUP00000021640	DEAD-box helicase 46.	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.	0.945
DDX46	G1QEQ4_MYOLU	ENSMLUP00000011486	ENSMLUP00000022187	DEAD-box helicase 46.	Uncharacterized protein.	0.876
DDX46	LOC102434604	ENSMLUP00000011486	ENSMLUP00000022065	DEAD-box helicase 46.	Sm domain-containing protein.	0.906
DDX46	LOC102437528	ENSMLUP00000011486	ENSMLUP00000022413	DEAD-box helicase 46.	annotation not available	0.906
DDX46	PHF5A	ENSMLUP00000011486	ENSMLUP00000002239	DEAD-box helicase 46.	PHD finger protein 5A.	0.998
DDX46	SF3A1	ENSMLUP00000011486	ENSMLUP00000001954	DEAD-box helicase 46.	Splicing factor 3a subunit 1.	0.999
DDX46	SF3A3	ENSMLUP00000011486	ENSMLUP00000000902	DEAD-box helicase 46.	Splicing factor 3a subunit 3.	0.999
DDX46	SF3B1	ENSMLUP00000011486	ENSMLUP00000000782	DEAD-box helicase 46.	Splicing factor 3b subunit 1.	0.999
DDX46	SF3B2	ENSMLUP00000011486	ENSMLUP00000010170	DEAD-box helicase 46.	Splicing factor 3b subunit 2.	0.995
DDX46	SF3B3	ENSMLUP00000011486	ENSMLUP00000013298	DEAD-box helicase 46.	Splicing factor 3b subunit 3.	0.999
DDX46	SF3B4	ENSMLUP00000011486	ENSMLUP00000009824	DEAD-box helicase 46.	Splicing factor 3b subunit 4.	0.990
DDX46	SF3B5	ENSMLUP00000011486	ENSMLUP00000007710	DEAD-box helicase 46.	Splicing factor 3B subunit 5; Belongs to the SF3B5 family.	0.969
DDX46	SF3B6	ENSMLUP00000011486	ENSMLUP00000002244	DEAD-box helicase 46.	Splicing factor 3b subunit 6.	0.950
DDX46	SNRNP70	ENSMLUP00000011486	ENSMLUP00000010717	DEAD-box helicase 46.	Small nuclear ribonucleoprotein U1 subunit 70.	0.772