(7 nodes) Mixed, incl. alpha1-adrenergic receptor activity, and alpha-2A adrenergic receptor binding network (Myotis lucifugus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	GNAQ	G protein subunit alpha q. (316 aa)
	GNB1	G protein subunit beta 1. (340 aa)
	GRK2	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (652 aa)
	ADRA1B	Adrenoceptor alpha 1B. (517 aa)
	ADRA1A	Adrenoceptor alpha 1A. (466 aa)
	ADRA1D	Adrenoceptor alpha 1D. (565 aa)

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRA1A	ADRA1B	ENSMLUP00000016773	ENSMLUP00000009218	Adrenoceptor alpha 1A.	Adrenoceptor alpha 1B.	0.922
ADRA1A	ADRA1D	ENSMLUP00000016773	ENSMLUP00000022637	Adrenoceptor alpha 1A.	Adrenoceptor alpha 1D.	0.918
ADRA1A	GNAQ	ENSMLUP00000016773	ENSMLUP00000003410	Adrenoceptor alpha 1A.	G protein subunit alpha q.	0.918
ADRA1A	GNB1	ENSMLUP00000016773	ENSMLUP00000003650	Adrenoceptor alpha 1A.	G protein subunit beta 1.	0.807
ADRA1A	GNG2	ENSMLUP00000016773	ENSMLUP00000001955	Adrenoceptor alpha 1A.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.780
ADRA1A	GRK2	ENSMLUP00000016773	ENSMLUP00000004630	Adrenoceptor alpha 1A.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.671
ADRA1B	ADRA1A	ENSMLUP00000009218	ENSMLUP00000016773	Adrenoceptor alpha 1B.	Adrenoceptor alpha 1A.	0.922
ADRA1B	ADRA1D	ENSMLUP00000009218	ENSMLUP00000022637	Adrenoceptor alpha 1B.	Adrenoceptor alpha 1D.	0.964
ADRA1B	GNAQ	ENSMLUP00000009218	ENSMLUP00000003410	Adrenoceptor alpha 1B.	G protein subunit alpha q.	0.912
ADRA1B	GNB1	ENSMLUP00000009218	ENSMLUP00000003650	Adrenoceptor alpha 1B.	G protein subunit beta 1.	0.818
ADRA1B	GNG2	ENSMLUP00000009218	ENSMLUP00000001955	Adrenoceptor alpha 1B.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.810
ADRA1B	GRK2	ENSMLUP00000009218	ENSMLUP00000004630	Adrenoceptor alpha 1B.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.727
ADRA1D	ADRA1A	ENSMLUP00000022637	ENSMLUP00000016773	Adrenoceptor alpha 1D.	Adrenoceptor alpha 1A.	0.918
ADRA1D	ADRA1B	ENSMLUP00000022637	ENSMLUP00000009218	Adrenoceptor alpha 1D.	Adrenoceptor alpha 1B.	0.964
ADRA1D	GNAQ	ENSMLUP00000022637	ENSMLUP00000003410	Adrenoceptor alpha 1D.	G protein subunit alpha q.	0.915
ADRA1D	GNB1	ENSMLUP00000022637	ENSMLUP00000003650	Adrenoceptor alpha 1D.	G protein subunit beta 1.	0.818
ADRA1D	GNG2	ENSMLUP00000022637	ENSMLUP00000001955	Adrenoceptor alpha 1D.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.810
ADRA1D	GRK2	ENSMLUP00000022637	ENSMLUP00000004630	Adrenoceptor alpha 1D.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.727
GNAQ	ADRA1A	ENSMLUP00000003410	ENSMLUP00000016773	G protein subunit alpha q.	Adrenoceptor alpha 1A.	0.918
GNAQ	ADRA1B	ENSMLUP00000003410	ENSMLUP00000009218	G protein subunit alpha q.	Adrenoceptor alpha 1B.	0.912