STRINGSTRING
YAP1 YAP1 MED30 MED30 LDB2 LDB2 WNT9B WNT9B NR2E1 NR2E1 MED15 MED15 MED12 MED12 SALL4 SALL4 BRAF BRAF MED21 MED21 G1PBE1_MYOLU G1PBE1_MYOLU HES1 HES1 LDB1 LDB1 NOG NOG FGF4 FGF4 BMPR1A BMPR1A MED17 MED17 LIF LIF KLF10 KLF10 HAVCR2 HAVCR2 SFRP1 SFRP1 REST REST VPS72 VPS72 NODAL NODAL ZFP36L2 ZFP36L2 STAT3 STAT3 RAF1 RAF1 LIG4 LIG4 ENSMLUP00000019443 ENSMLUP00000019443 G1Q6X6_MYOLU G1Q6X6_MYOLU SOX9 SOX9 LOC102428025 LOC102428025 FGF10 FGF10 ZHX2 ZHX2 G1QFJ2_MYOLU G1QFJ2_MYOLU MED15-2 MED15-2 RIF1 RIF1 CUL4A CUL4A NIPBL NIPBL LRP5 LRP5 MED14 MED14 G1NT50_MYOLU G1NT50_MYOLU SMC1A SMC1A CDX2 CDX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
YAP1Yes associated protein 1. (397 aa)
MED30Mediator complex subunit 30. (149 aa)
LDB2LIM domain binding 2. (292 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (423 aa)
MED15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (750 aa)
MED12Mediator complex subunit 12. (2187 aa)
SALL4Uncharacterized protein. (1008 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (792 aa)
MED21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (143 aa)
G1PBE1_MYOLUUncharacterized protein. (993 aa)
HES1Hes family bHLH transcription factor 1. (279 aa)
LDB1LIM domain binding 1. (417 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (652 aa)
LIFUncharacterized protein. (85 aa)
KLF10Kruppel like factor 10. (482 aa)
HAVCR2Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (471 aa)
SFRP1Secreted frizzled related protein 1. (212 aa)
RESTRE1 silencing transcription factor. (952 aa)
VPS72Vacuolar protein sorting 72 homolog. (373 aa)
NODALNodal growth differentiation factor. (347 aa)
ZFP36L2C3H1-type domain-containing protein. (351 aa)
STAT3Signal transducer and activator of transcription. (773 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
LIG4DNA ligase. (911 aa)
ENSMLUP00000019443annotation not available (120 aa)
G1Q6X6_MYOLUUncharacterized protein. (1021 aa)
SOX9SRY-box transcription factor 9. (367 aa)
LOC102428025Uncharacterized protein. (311 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ZHX2Zinc fingers and homeoboxes 2. (843 aa)
G1QFJ2_MYOLUUncharacterized protein. (176 aa)
MED15-2Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (366 aa)
RIF1Replication timing regulatory factor 1. (2222 aa)
CUL4ACullin 4A; Belongs to the cullin family. (764 aa)
NIPBLNipped-B protein. (2798 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1607 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1456 aa)
G1NT50_MYOLUUncharacterized protein. (243 aa)
SMC1AStructural maintenance of chromosomes protein. (1235 aa)
CDX2Caudal type homeobox 2. (190 aa)
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.