132 items (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G1PR40_MYOLU	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (331 aa)
	G1Q0N2_MYOLU	Glucose-6-phosphate isomerase; Belongs to the GPI family. (525 aa)
	G1PYA8_MYOLU	Uncharacterized protein. (328 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (388 aa)
	RAF1	Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
	STAT3	Signal transducer and activator of transcription. (773 aa)
	G1PBM2_MYOLU	Uncharacterized protein. (820 aa)
	HECTD4	HECT domain E3 ubiquitin protein ligase 4. (3995 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (243 aa)
	SIDT2	SID1 transmembrane family member 2. (772 aa)
	GAS6	Growth arrest specific 6. (670 aa)
	APPL2	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (662 aa)
	PRCP	Prolylcarboxypeptidase. (451 aa)
	PDK2	Protein-serine/threonine kinase. (408 aa)
	PDK4	Protein-serine/threonine kinase. (437 aa)
	BAD	BCL2 associated agonist of cell death. (174 aa)
	G1P850_MYOLU	DUF3496 domain-containing protein. (1047 aa)
	FBN1	Fibrillin 1. (3536 aa)
	MBD5	Methyl-CpG binding domain protein 5. (1758 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (244 aa)
	AGER	Advanced glycosylation end-product specific receptor. (435 aa)
	ASPSCR1	UBX domain-containing protein. (411 aa)
	FOXK2	Forkhead box K2. (520 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1155 aa)
	STXBP5L	Syntaxin binding protein 5 like. (1186 aa)
	NOX4	NADPH oxidase 4. (578 aa)
	ERN1	Endoplasmic reticulum to nucleus signaling 1. (974 aa)
	GPR1	G protein-coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	CRY1	Cryptochrome circadian regulator 1. (588 aa)
	PTCH1	Patched 1. (1435 aa)
	TFAP2B	Transcription factor AP-2 beta. (457 aa)
	ADIPOR1	Uncharacterized protein. (375 aa)
	IL6	Interleukin 6. (208 aa)
	FAM3B	Family with sequence similarity 3 member B. (233 aa)
	CRY2	Cryptochrome circadian regulator 2. (614 aa)
	PYGL	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (771 aa)
	HK3	Hexokinase 3. (924 aa)
	LEP	Leptin. (139 aa)
	KAT5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
	TCF7L2	Transcription factor 7 like 2. (437 aa)
	HK2	Hexokinase 2. (917 aa)
	HNF1A	HNF1 homeobox A. (628 aa)
	PIK3CA	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1070 aa)
	NR1H4	Nuclear receptor subfamily 1 group H member 4. (482 aa)
	KLF7	Kruppel like factor 7. (302 aa)
	FABP5	Fatty acid binding protein 5. (109 aa)
	PCK2	Phosphoenolpyruvate carboxykinase 2, mitochondrial. (662 aa)
	SIN3A	SIN3 transcription regulator family member A. (1275 aa)
	TFAP2E	Transcription factor AP-2 epsilon. (256 aa)
	CCDC186	Coiled-coil domain containing 186. (917 aa)
	CSMD2	CUB and Sushi multiple domains 2. (3460 aa)
	FOXK1	Forkhead box K1. (544 aa)
	CYB5R4	Cytochrome b5 reductase 4. (520 aa)
	STXBP3	Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa)
	NR1D1	Nuclear receptor subfamily 1 group D member 1. (610 aa)
	SLC39A14	Solute carrier family 39 member 14. (487 aa)
	PDX1	Pancreatic and duodenal homeobox 1. (282 aa)
	PCK1	Phosphoenolpyruvate carboxykinase 1. (624 aa)
	LRRC8A	Leucine rich repeat containing 8 VRAC subunit A. (806 aa)
	CCDC115	Coiled-coil domain containing 115. (180 aa)
	NUCKS1	Uncharacterized protein. (239 aa)
	GCK	Phosphotransferase. (438 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
	FFAR2	Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa)
	FFAR3	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (318 aa)
	TRPV4	Transient receptor potential cation channel subfamily V member 4. (493 aa)
	DHPS	Uncharacterized protein. (369 aa)
	HKDC1	Hexokinase domain containing 1. (917 aa)
	HK1	Hexokinase 1. (949 aa)
	G1PLD1_MYOLU	FYVE_2 domain-containing protein. (196 aa)
	PLSCR3	Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (302 aa)
	MCU	Mitochondrial calcium uniporter. (278 aa)
	INSR	Tyrosine-protein kinase receptor. (1336 aa)
	ZBTB20	Zinc finger and BTB domain containing 20. (741 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (517 aa)
	PRKAA2	Non-specific serine/threonine protein kinase. (528 aa)
	SESN3	Sestrin 3. (470 aa)
	BACE2	Beta-secretase 2; Belongs to the peptidase A1 family. (415 aa)
	CSRP3	Cysteine and glycine rich protein 3. (194 aa)
	PTPN11	Protein tyrosine phosphatase non-receptor type 11. (379 aa)
	RFX6	Regulatory factor X6. (928 aa)
	PAX6	Paired box 6. (422 aa)
	TRA2B	Transformer 2 beta homolog. (287 aa)
	CCN4	Cellular communication network factor 4. (272 aa)
	MLXIPL	MLX interacting protein like. (700 aa)
	ADGRF5	Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1343 aa)
	CYP7A1	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa)
	SLC12A6	Solute carrier family 12 member 6. (1150 aa)
	SLC37A4	Solute carrier family 37 member 4. (429 aa)
	L7N171_MYOLU	ANK_REP_REGION domain-containing protein. (1720 aa)
	SLC2A4	Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
	SIRT1	Sirtuin 1. (610 aa)
	RBM4	RNA binding motif protein 4. (382 aa)
	PIK3R2	Uncharacterized protein. (730 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
	CNR1	Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (471 aa)
	ALOX5	Arachidonate 5-lipoxygenase. (674 aa)
	NCOA5	Nuclear receptor coactivator 5. (577 aa)
	KCNB1	Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (834 aa)
	GPI	Glucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)
	CARTPT	CART prepropeptide. (115 aa)
	FOXO3	Forkhead box O3. (672 aa)
	ADIPOR2	Uncharacterized protein. (386 aa)
	PARK7	Parkinsonism associated deglycase. (189 aa)
	INPP5K	Inositol polyphosphate-5-phosphatase K. (464 aa)
	HNF4A	Hepatocyte nuclear factor 4 alpha. (474 aa)
	STK11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (441 aa)
	RAB11FIP2	RAB11 family interacting protein 2. (512 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (826 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	RACK1	Receptor for activated C kinase 1. (316 aa)
	BHLHA15	Basic helix-loop-helix family member a15. (187 aa)
	NGFR	Nerve growth factor receptor. (432 aa)
	LRRC8D	Leucine rich repeat containing 8 VRAC subunit D. (858 aa)
	LEPR	Leptin receptor. (1149 aa)
	G1Q2X6_MYOLU	Uncharacterized protein. (386 aa)
	RMI1	RecQ mediated genome instability 1. (616 aa)
	G1Q3H7_MYOLU	Uncharacterized protein. (386 aa)
	GPER1	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa)
	VGF	VGF nerve growth factor inducible. (619 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	G1Q5P8_MYOLU	Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (139 aa)
	PTPRN2	Uncharacterized protein. (184 aa)
	G1Q7Z7_MYOLU	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (336 aa)
	FOXA1	Forkhead box A1. (464 aa)
	G1QAW8_MYOLU	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (249 aa)
	G1QAY9_MYOLU	Uncharacterized protein. (239 aa)
	G1QBB3_MYOLU	SH2 domain-containing protein. (270 aa)
	G1QD05_MYOLU	Uncharacterized protein. (389 aa)
	FFAR1	Free fatty acid receptor 1. (300 aa)
	G6PC2	Glucose-6-phosphatase catalytic subunit 2. (358 aa)
	G1QEB1_MYOLU	SH2 domain-containing protein. (266 aa)

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY8	CNR1	ENSMLUP00000011119	ENSMLUP00000013631	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...]	0.880
ADCY8	G1QAW8_MYOLU	ENSMLUP00000011119	ENSMLUP00000020851	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.684
ADCY8	PRKACA	ENSMLUP00000011119	ENSMLUP00000007530	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.923
ADGRF5	INPP5K	ENSMLUP00000004979	ENSMLUP00000001661	Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family.	Inositol polyphosphate-5-phosphatase K.	0.572
ADIPOQ	ADIPOR1	ENSMLUP00000000397	ENSMLUP00000014668	Adiponectin, C1Q and collagen domain containing.	Uncharacterized protein.	0.962
ADIPOQ	ADIPOR2	ENSMLUP00000000397	ENSMLUP00000002016	Adiponectin, C1Q and collagen domain containing.	Uncharacterized protein.	0.949
ADIPOQ	APPL2	ENSMLUP00000000397	ENSMLUP00000006780	Adiponectin, C1Q and collagen domain containing.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.576
ADIPOQ	CCDC115	ENSMLUP00000000397	ENSMLUP00000010333	Adiponectin, C1Q and collagen domain containing.	Coiled-coil domain containing 115.	0.686
ADIPOQ	FABP5	ENSMLUP00000000397	ENSMLUP00000008663	Adiponectin, C1Q and collagen domain containing.	Fatty acid binding protein 5.	0.468
ADIPOQ	G1Q2X6_MYOLU	ENSMLUP00000000397	ENSMLUP00000018059	Adiponectin, C1Q and collagen domain containing.	Uncharacterized protein.	0.949
ADIPOQ	G1Q3H7_MYOLU	ENSMLUP00000000397	ENSMLUP00000018260	Adiponectin, C1Q and collagen domain containing.	Uncharacterized protein.	0.949
ADIPOQ	G1QD05_MYOLU	ENSMLUP00000000397	ENSMLUP00000021588	Adiponectin, C1Q and collagen domain containing.	Uncharacterized protein.	0.962
ADIPOQ	G6PC2	ENSMLUP00000000397	ENSMLUP00000022039	Adiponectin, C1Q and collagen domain containing.	Glucose-6-phosphatase catalytic subunit 2.	0.577
ADIPOQ	IL6	ENSMLUP00000000397	ENSMLUP00000014444	Adiponectin, C1Q and collagen domain containing.	Interleukin 6.	0.718
ADIPOQ	INS	ENSMLUP00000000397	ENSMLUP00000003521	Adiponectin, C1Q and collagen domain containing.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.769
ADIPOQ	INSR	ENSMLUP00000000397	ENSMLUP00000012576	Adiponectin, C1Q and collagen domain containing.	Tyrosine-protein kinase receptor.	0.487
ADIPOQ	KLF7	ENSMLUP00000000397	ENSMLUP00000008598	Adiponectin, C1Q and collagen domain containing.	Kruppel like factor 7.	0.418
ADIPOQ	LEP	ENSMLUP00000000397	ENSMLUP00000007809	Adiponectin, C1Q and collagen domain containing.	Leptin.	0.917
ADIPOQ	LEPR	ENSMLUP00000000397	ENSMLUP00000018023	Adiponectin, C1Q and collagen domain containing.	Leptin receptor.	0.619
ADIPOQ	PCK1	ENSMLUP00000000397	ENSMLUP00000010070	Adiponectin, C1Q and collagen domain containing.	Phosphoenolpyruvate carboxykinase 1.	0.559