46 items (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHODL	Chondrolectin. (293 aa)
	ISLR2	Immunoglobulin superfamily containing leucine rich repeat 2. (747 aa)
	LIMK1	LIM domain kinase 1. (633 aa)
	SLITRK1	SLIT and NTRK like family member 1. (698 aa)
	PLXNC1	Plexin C1. (1173 aa)
	TRPV2	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (752 aa)
	NIN	Ninein. (2072 aa)
	MAP6	Microtubule associated protein 6. (816 aa)
	PLXNB3	Plexin B3. (1709 aa)
	MAP3K13	Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (963 aa)
	G1P702_MYOLU	IF rod domain-containing protein; Belongs to the intermediate filament family. (341 aa)
	PLXNA4	Plexin A4. (1896 aa)
	PLXNA2	Plexin A2. (1888 aa)
	CDKL5	Cyclin dependent kinase like 5. (882 aa)
	STK25	Serine/threonine kinase 25. (426 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (792 aa)
	PLXNA1	Plexin A1. (1895 aa)
	NTN1	Netrin 1. (418 aa)
	SRF	Serum response factor. (325 aa)
	ZFYVE27	Zinc finger FYVE-type containing 27. (415 aa)
	OCM	Uncharacterized protein; Belongs to the parvalbumin family. (109 aa)
	EFNA5	Ephrin A5; Belongs to the ephrin family. (187 aa)
	PLXNA3	Plexin A3. (1712 aa)
	NGF	Nerve growth factor; Belongs to the NGF-beta family. (241 aa)
	TIAM2	T cell lymphoma invasion and metastasis 2. (1621 aa)
	LAYN	Layilin. (384 aa)
	SEMA7A	Semaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (664 aa)
	DBNL	Drebrin like. (423 aa)
	LPAR3	Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (356 aa)
	IST1	IST1 factor associated with ESCRT-III. (366 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
	PLXND1	Plexin D1. (1808 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (775 aa)
	STK11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (441 aa)
	POU4F2	POU domain protein. (405 aa)
	SHTN1	Shootin 1. (609 aa)
	BDNF	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (247 aa)
	MEGF8	Multiple EGF like domains 8. (2849 aa)
	GOLGA4	Golgin A4. (2205 aa)
	LOC102419820	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (414 aa)
	G1Q372_MYOLU	Uncharacterized protein. (358 aa)
	PKHD1L1	PKHD1 like 1. (4269 aa)
	WNT3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (329 aa)
	G1Q6K5_MYOLU	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (169 aa)
	ISLR	Immunoglobulin superfamily containing leucine rich repeat. (423 aa)
	G1Q9P6_MYOLU	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (89 aa)

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDNF	BMPR2	ENSMLUP00000014516	ENSMLUP00000013454	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.456
BDNF	BRAF	ENSMLUP00000014516	ENSMLUP00000006913	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	B-Raf proto-oncogene, serine/threonine kinase.	0.456
BDNF	G1P702_MYOLU	ENSMLUP00000014516	ENSMLUP00000005871	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.487
BDNF	LIMK1	ENSMLUP00000014516	ENSMLUP00000000374	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	LIM domain kinase 1.	0.563
BDNF	NTN1	ENSMLUP00000014516	ENSMLUP00000007835	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Netrin 1.	0.582
BDNF	PLXNA1	ENSMLUP00000014516	ENSMLUP00000007289	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Plexin A1.	0.489
BDNF	PLXNA2	ENSMLUP00000014516	ENSMLUP00000006209	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Plexin A2.	0.525
BDNF	PLXNA3	ENSMLUP00000014516	ENSMLUP00000009154	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Plexin A3.	0.524
BDNF	PLXNA4	ENSMLUP00000014516	ENSMLUP00000005888	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Plexin A4.	0.487
BDNF	PLXNB3	ENSMLUP00000014516	ENSMLUP00000004040	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Plexin B3.	0.476
BMPR2	BDNF	ENSMLUP00000013454	ENSMLUP00000014516	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	0.456
BMPR2	LIMK1	ENSMLUP00000013454	ENSMLUP00000000374	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	LIM domain kinase 1.	0.942
BRAF	BDNF	ENSMLUP00000006913	ENSMLUP00000014516	B-Raf proto-oncogene, serine/threonine kinase.	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	0.456
BRAF	LIMK1	ENSMLUP00000006913	ENSMLUP00000000374	B-Raf proto-oncogene, serine/threonine kinase.	LIM domain kinase 1.	0.464
DBNL	NIN	ENSMLUP00000010870	ENSMLUP00000003016	Drebrin like.	Ninein.	0.403
EFNA5	NTN1	ENSMLUP00000009047	ENSMLUP00000007835	Ephrin A5; Belongs to the ephrin family.	Netrin 1.	0.487
EFNA5	PLXNA1	ENSMLUP00000009047	ENSMLUP00000007289	Ephrin A5; Belongs to the ephrin family.	Plexin A1.	0.709
EFNA5	PLXNA2	ENSMLUP00000009047	ENSMLUP00000006209	Ephrin A5; Belongs to the ephrin family.	Plexin A2.	0.461
EFNA5	PLXNA3	ENSMLUP00000009047	ENSMLUP00000009154	Ephrin A5; Belongs to the ephrin family.	Plexin A3.	0.461
EFNA5	PLXNA4	ENSMLUP00000009047	ENSMLUP00000005888	Ephrin A5; Belongs to the ephrin family.	Plexin A4.	0.461