36 items (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	UCN	Urocortin. (128 aa)
	OPHN1	Oligophrenin 1. (670 aa)
	FRRS1L	Ferric chelate reductase 1 like. (256 aa)
	SERPINE2	Serpin family E member 2; Belongs to the serpin family. (407 aa)
	ATAD1	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (365 aa)
	DGKI	Diacylglycerol kinase. (932 aa)
	CLN3	Battenin. (444 aa)
	GRM1	Glutamate metabotropic receptor 1. (1205 aa)
	GRM2	Glutamate metabotropic receptor 2. (870 aa)
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (447 aa)
	SYT1	Synaptotagmin 1. (369 aa)
	GRIK2	Glutamate ionotropic receptor kainate type subunit 2. (870 aa)
	TPRG1	Tumor protein p63 regulated 1. (279 aa)
	LRRK2	Leucine rich repeat kinase 2. (2530 aa)
	DGKZ	Diacylglycerol kinase. (1115 aa)
	RELN	Reelin. (3281 aa)
	G1PFG4_MYOLU	Uncharacterized protein. (700 aa)
	MAPK8IP2	Mitogen-activated protein kinase 8 interacting protein 2. (811 aa)
	HOMER1	Homer scaffold protein 1. (364 aa)
	LOC102442662	G_PROTEIN_RECEP_F3_4 domain-containing protein. (415 aa)
	CCL2	C-C motif chemokine. (109 aa)
	GRM8	Glutamate metabotropic receptor 8. (908 aa)
	L7N1Q1_MYOLU	Uncharacterized protein. (399 aa)
	CACNG4	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (247 aa)
	SYT2	Synaptotagmin 2. (268 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (294 aa)
	TNR	Tenascin R. (1359 aa)
	CACNG2	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (256 aa)
	GRM5	Glutamate metabotropic receptor 5. (846 aa)
	G1PV98_MYOLU	G_PROTEIN_RECEP_F3_4 domain-containing protein. (455 aa)
	G1PWV0_MYOLU	G_PROTEIN_RECEP_F3_4 domain-containing protein. (511 aa)
	G1Q0A1_MYOLU	ANF_receptor domain-containing protein. (172 aa)
	GRM6	Glutamate metabotropic receptor 6. (857 aa)
	G1QA58_MYOLU	ANF_receptor domain-containing protein. (173 aa)
	CACNG3	Calcium voltage-gated channel auxiliary subunit gamma 3. (246 aa)
	G1QDR0_MYOLU	Uncharacterized protein. (89 aa)

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACNG2	CACNG3	ENSMLUP00000014455	ENSMLUP00000021650	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Calcium voltage-gated channel auxiliary subunit gamma 3.	0.847
CACNG2	CACNG4	ENSMLUP00000014455	ENSMLUP00000012906	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.825
CACNG3	CACNG2	ENSMLUP00000021650	ENSMLUP00000014455	Calcium voltage-gated channel auxiliary subunit gamma 3.	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.847
CACNG3	CACNG4	ENSMLUP00000021650	ENSMLUP00000012906	Calcium voltage-gated channel auxiliary subunit gamma 3.	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.824
CACNG4	CACNG2	ENSMLUP00000012906	ENSMLUP00000014455	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.825
CACNG4	CACNG3	ENSMLUP00000012906	ENSMLUP00000021650	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Calcium voltage-gated channel auxiliary subunit gamma 3.	0.824
CDK5	G1PFG4_MYOLU	ENSMLUP00000013385	ENSMLUP00000009312	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.422
CDK5	L7N1Q1_MYOLU	ENSMLUP00000013385	ENSMLUP00000012755	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.422
CDK5	LRRK2	ENSMLUP00000013385	ENSMLUP00000008555	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Leucine rich repeat kinase 2.	0.586
G1PFG4_MYOLU	CDK5	ENSMLUP00000009312	ENSMLUP00000013385	Uncharacterized protein.	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	0.422
G1PFG4_MYOLU	G1PV98_MYOLU	ENSMLUP00000009312	ENSMLUP00000015245	Uncharacterized protein.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.425
G1PFG4_MYOLU	G1PWV0_MYOLU	ENSMLUP00000009312	ENSMLUP00000015894	Uncharacterized protein.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.420
G1PFG4_MYOLU	G1Q0A1_MYOLU	ENSMLUP00000009312	ENSMLUP00000017133	Uncharacterized protein.	ANF_receptor domain-containing protein.	0.420
G1PFG4_MYOLU	G1QA58_MYOLU	ENSMLUP00000009312	ENSMLUP00000020591	Uncharacterized protein.	ANF_receptor domain-containing protein.	0.420
G1PFG4_MYOLU	GRM1	ENSMLUP00000009312	ENSMLUP00000004113	Uncharacterized protein.	Glutamate metabotropic receptor 1.	0.493
G1PFG4_MYOLU	GRM5	ENSMLUP00000009312	ENSMLUP00000014762	Uncharacterized protein.	Glutamate metabotropic receptor 5.	0.523
G1PFG4_MYOLU	GRM6	ENSMLUP00000009312	ENSMLUP00000020142	Uncharacterized protein.	Glutamate metabotropic receptor 6.	0.420
G1PFG4_MYOLU	GRM8	ENSMLUP00000009312	ENSMLUP00000010584	Uncharacterized protein.	Glutamate metabotropic receptor 8.	0.420
G1PFG4_MYOLU	HOMER1	ENSMLUP00000009312	ENSMLUP00000009991	Uncharacterized protein.	Homer scaffold protein 1.	0.923
G1PFG4_MYOLU	L7N1Q1_MYOLU	ENSMLUP00000009312	ENSMLUP00000012755	Uncharacterized protein.	Uncharacterized protein.	0.897