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MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1575 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa) | ||||
MED16 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (833 aa) | ||||
ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1480 aa) | ||||
HNF1B | HNF1 homeobox B. (557 aa) | ||||
ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (297 aa) | ||||
TAF12 | TATA-box binding protein associated factor 12. (161 aa) | ||||
MED8 | Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (268 aa) | ||||
SUB1 | PC4 domain-containing protein. (134 aa) | ||||
ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (551 aa) | ||||
LOC102422576 | Uncharacterized protein. (434 aa) | ||||
G1PVA9_MYOLU | TAFH domain-containing protein. (747 aa) | ||||
GTF2A1 | Uncharacterized protein. (380 aa) | ||||
G1PZ51_MYOLU | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (388 aa) | ||||
G1PZL5_MYOLU | Uncharacterized protein. (693 aa) | ||||
G1Q7H9_MYOLU | TAF domain-containing protein. (439 aa) | ||||
G1Q3D2_MYOLU | Homeobox domain-containing protein. (309 aa) | ||||
G1Q2W7_MYOLU | TAF6_C domain-containing protein. (482 aa) | ||||
G1Q221_MYOLU | TAF domain-containing protein. (426 aa) | ||||
G1Q1F3_MYOLU | PC4 domain-containing protein. (134 aa) | ||||
TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (144 aa) | ||||
G1PZQ5_MYOLU | Uncharacterized protein. (371 aa) | ||||
PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa) | ||||
MED4-2 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (234 aa) | ||||
LOC102437556 | TAFH domain-containing protein. (494 aa) | ||||
G1Q8T5_MYOLU | Uncharacterized protein. (80 aa) | ||||
TAF2 | TATA-box binding protein associated factor 2. (1198 aa) | ||||
TAF4 | TATA-box binding protein associated factor 4. (637 aa) | ||||
WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (402 aa) | ||||
TAF5 | TATA-box binding protein associated factor 5. (615 aa) | ||||
MED24 | Mediator complex subunit 24. (925 aa) | ||||
MED13 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2177 aa) | ||||
TAF8 | TATA-box binding protein associated factor 8. (310 aa) | ||||
G1PCP6_MYOLU | Uncharacterized protein. (218 aa) | ||||
MED17 | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (652 aa) | ||||
SRF | Serum response factor. (325 aa) | ||||
MED30 | Mediator complex subunit 30. (149 aa) | ||||
DHX36 | DEAH-box helicase 36. (1005 aa) | ||||
TAF3 | TATA-box binding protein associated factor 3. (796 aa) | ||||
MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (269 aa) | ||||
MED14 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1456 aa) | ||||
MED12 | Mediator complex subunit 12. (2187 aa) |