node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARID5A | SMARCB1 | ENSMLUP00000018721 | ENSMLUP00000004537 | AT-rich interaction domain 5A. | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. | 0.709 |
AUTS2 | MAPK3 | ENSMLUP00000004199 | ENSMLUP00000010279 | Activator of transcription and developmental regulator AUTS2. | Mitogen-activated protein kinase. | 0.518 |
AUTS2 | PRKAA1 | ENSMLUP00000004199 | ENSMLUP00000012958 | Activator of transcription and developmental regulator AUTS2. | Non-specific serine/threonine protein kinase. | 0.428 |
AUTS2 | PRKAA2 | ENSMLUP00000004199 | ENSMLUP00000012975 | Activator of transcription and developmental regulator AUTS2. | Non-specific serine/threonine protein kinase. | 0.428 |
BRCA1 | BRD7 | ENSMLUP00000003770 | ENSMLUP00000012097 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Bromo domain-containing protein. | 0.679 |
BRCA1 | G1PZL5_MYOLU | ENSMLUP00000003770 | ENSMLUP00000016897 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Uncharacterized protein. | 0.877 |
BRCA1 | G1QC70_MYOLU | ENSMLUP00000003770 | ENSMLUP00000021303 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Bromo domain-containing protein. | 0.679 |
BRCA1 | GATA3 | ENSMLUP00000003770 | ENSMLUP00000013490 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | GATA binding protein 3. | 0.411 |
BRCA1 | KAT7 | ENSMLUP00000003770 | ENSMLUP00000010098 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | 0.641 |
BRCA1 | LOC102422576 | ENSMLUP00000003770 | ENSMLUP00000013116 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Uncharacterized protein. | 0.877 |
BRCA1 | MUC1 | ENSMLUP00000003770 | ENSMLUP00000003862 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | SEA domain-containing protein. | 0.475 |
BRCA1 | PML | ENSMLUP00000003770 | ENSMLUP00000010693 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Promyelocytic leukemia. | 0.441 |
BRCA1 | SMAD4 | ENSMLUP00000003770 | ENSMLUP00000012691 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Mothers against decapentaplegic homolog. | 0.480 |
BRCA1 | SMARCB1 | ENSMLUP00000003770 | ENSMLUP00000004537 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. | 0.501 |
BRD7 | BRCA1 | ENSMLUP00000012097 | ENSMLUP00000003770 | Bromo domain-containing protein. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.679 |
BRD7 | KAT7 | ENSMLUP00000012097 | ENSMLUP00000010098 | Bromo domain-containing protein. | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | 0.577 |
BRD7 | SMARCB1 | ENSMLUP00000012097 | ENSMLUP00000004537 | Bromo domain-containing protein. | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. | 0.996 |
DIP2B | MAPK3 | ENSMLUP00000004908 | ENSMLUP00000010279 | Disco interacting protein 2 homolog B. | Mitogen-activated protein kinase. | 0.450 |
DIP2C | MAPK3 | ENSMLUP00000013377 | ENSMLUP00000010279 | Disco interacting protein 2 homolog C. | Mitogen-activated protein kinase. | 0.450 |
FOXP3 | GATA3 | ENSMLUP00000005222 | ENSMLUP00000013490 | Forkhead box P3. | GATA binding protein 3. | 0.869 |