30 items (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G1Q773_MYOLU	Uncharacterized protein. (71 aa)
	ARID5A	AT-rich interaction domain 5A. (594 aa)
	G1PZL5_MYOLU	Uncharacterized protein. (693 aa)
	GATA3	GATA binding protein 3. (443 aa)
	TADA2A	Transcriptional adapter. (445 aa)
	DIP2C	Disco interacting protein 2 homolog C. (1530 aa)
	LOC102422576	Uncharacterized protein. (434 aa)
	PRKAA2	Non-specific serine/threonine protein kinase. (528 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (517 aa)
	SMAD4	Mothers against decapentaplegic homolog. (554 aa)
	BRD7	Bromo domain-containing protein. (595 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
	GLYR1	Glyoxylate reductase 1 homolog. (553 aa)
	LIF	Uncharacterized protein. (85 aa)
	PML	Promyelocytic leukemia. (875 aa)
	MAPK3	Mitogen-activated protein kinase. (370 aa)
	KAT7	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
	RUVBL2	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (264 aa)
	TADA2B	Transcriptional adaptor 2B. (328 aa)
	SPHK2	DAGKc domain-containing protein. (758 aa)
	FOXP3	Forkhead box P3. (348 aa)
	DIP2B	Disco interacting protein 2 homolog B. (1518 aa)
	SMARCB1	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
	RPS6KA5	Ribosomal protein S6 kinase. (770 aa)
	PIWIL2	Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (969 aa)
	BRCA1	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1852 aa)
	MUC1	SEA domain-containing protein. (274 aa)
	AUTS2	Activator of transcription and developmental regulator AUTS2. (1011 aa)
	PIH1D1	PIH1 domain containing 1. (290 aa)
	G1QC70_MYOLU	Bromo domain-containing protein. (239 aa)

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID5A	SMARCB1	ENSMLUP00000018721	ENSMLUP00000004537	AT-rich interaction domain 5A.	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family.	0.709
AUTS2	MAPK3	ENSMLUP00000004199	ENSMLUP00000010279	Activator of transcription and developmental regulator AUTS2.	Mitogen-activated protein kinase.	0.518
AUTS2	PRKAA1	ENSMLUP00000004199	ENSMLUP00000012958	Activator of transcription and developmental regulator AUTS2.	Non-specific serine/threonine protein kinase.	0.428
AUTS2	PRKAA2	ENSMLUP00000004199	ENSMLUP00000012975	Activator of transcription and developmental regulator AUTS2.	Non-specific serine/threonine protein kinase.	0.428
BRCA1	BRD7	ENSMLUP00000003770	ENSMLUP00000012097	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Bromo domain-containing protein.	0.679
BRCA1	G1PZL5_MYOLU	ENSMLUP00000003770	ENSMLUP00000016897	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Uncharacterized protein.	0.877
BRCA1	G1QC70_MYOLU	ENSMLUP00000003770	ENSMLUP00000021303	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Bromo domain-containing protein.	0.679
BRCA1	GATA3	ENSMLUP00000003770	ENSMLUP00000013490	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	GATA binding protein 3.	0.411
BRCA1	KAT7	ENSMLUP00000003770	ENSMLUP00000010098	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.641
BRCA1	LOC102422576	ENSMLUP00000003770	ENSMLUP00000013116	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Uncharacterized protein.	0.877
BRCA1	MUC1	ENSMLUP00000003770	ENSMLUP00000003862	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	SEA domain-containing protein.	0.475
BRCA1	PML	ENSMLUP00000003770	ENSMLUP00000010693	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Promyelocytic leukemia.	0.441
BRCA1	SMAD4	ENSMLUP00000003770	ENSMLUP00000012691	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Mothers against decapentaplegic homolog.	0.480
BRCA1	SMARCB1	ENSMLUP00000003770	ENSMLUP00000004537	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family.	0.501
BRD7	BRCA1	ENSMLUP00000012097	ENSMLUP00000003770	Bromo domain-containing protein.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.679
BRD7	KAT7	ENSMLUP00000012097	ENSMLUP00000010098	Bromo domain-containing protein.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.577
BRD7	SMARCB1	ENSMLUP00000012097	ENSMLUP00000004537	Bromo domain-containing protein.	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family.	0.996
DIP2B	MAPK3	ENSMLUP00000004908	ENSMLUP00000010279	Disco interacting protein 2 homolog B.	Mitogen-activated protein kinase.	0.450
DIP2C	MAPK3	ENSMLUP00000013377	ENSMLUP00000010279	Disco interacting protein 2 homolog C.	Mitogen-activated protein kinase.	0.450
FOXP3	GATA3	ENSMLUP00000005222	ENSMLUP00000013490	Forkhead box P3.	GATA binding protein 3.	0.869