STRINGSTRING
YWHAE YWHAE PLEC PLEC RIPK1 RIPK1 HMGB4 HMGB4 VIM VIM YWHAG YWHAG CASP8 CASP8 FAS FAS APC APC NMT1 NMT1 KPNB1 KPNB1 MAP2 MAP2 BOK BOK BCL2L10 BCL2L10 G1QER2_MYOLU G1QER2_MYOLU TMEM198 TMEM198 G1QD33_MYOLU G1QD33_MYOLU ENSMLUP00000021529 ENSMLUP00000021529 HMGB2 HMGB2 LMNA LMNA LOC102428639 LOC102428639 LOC102443111 LOC102443111 ENSMLUP00000020832 ENSMLUP00000020832 G1QAC1_MYOLU G1QAC1_MYOLU LOC102423054 LOC102423054 GSN GSN DFFA DFFA IGDCC3 IGDCC3 IGDCC4 IGDCC4 DAPK2 DAPK2 HP1BP3 HP1BP3 APPL1 APPL1 BNIP5 BNIP5 PRKCD PRKCD KPNA1 KPNA1 CASP6 CASP6 G1NUV7_MYOLU G1NUV7_MYOLU YWHAH YWHAH STK26 STK26 XIAP XIAP SATB1 SATB1 CASP3 CASP3 SEPTIN5 SEPTIN5 DUS4L DUS4L FNTA FNTA CD14 CD14 GSDMB GSDMB DSG1 DSG1 DSG3 DSG3 DSG2 DSG2 APC2 APC2 CASP7 CASP7 G1P1I5_MYOLU G1P1I5_MYOLU BCAP31 BCAP31 G1P2R3_MYOLU G1P2R3_MYOLU TJP1 TJP1 BCL2L2 BCL2L2 MAPT MAPT LOC102417162 LOC102417162 ADD1 ADD1 YWHAQ YWHAQ CFLAR CFLAR G1P5Y1_MYOLU G1P5Y1_MYOLU DAPK3 DAPK3 YWHAB YWHAB CDH1 CDH1 FASLG FASLG SEPTIN1 SEPTIN1 BAD BAD PMAIP1 PMAIP1 STK25 STK25 APPL2 APPL2 BCL2L1 BCL2L1 SPTAN1 SPTAN1 PPP3CC PPP3CC OCLN OCLN BMF BMF APAF1 APAF1 G1PBK4_MYOLU G1PBK4_MYOLU OPA1 OPA1 CTNNB1 CTNNB1 DSP DSP G1PDJ5_MYOLU G1PDJ5_MYOLU SCIN SCIN DCC DCC CASP9 CASP9 LMNB1 LMNB1 SFN SFN BAX BAX DYNLL1 DYNLL1 LOC102439769 LOC102439769 TJP3 TJP3 HMGB3 HMGB3 PTK2 PTK2 TRADD TRADD GSDME GSDME G1PHJ2_MYOLU G1PHJ2_MYOLU SH3GLB2 SH3GLB2 MAPK3 MAPK3 DBNL DBNL SH3GLB1 SH3GLB1 DAPK1 DAPK1 STK24 STK24 UNC5B UNC5B LMNB2 LMNB2 DNM1L DNM1L OMA1 OMA1 ROCK1 ROCK1 LMNTD1 LMNTD1 H1-0 H1-0 LOC102421025 LOC102421025 DYNLL2 DYNLL2 G1Q8P3_MYOLU G1Q8P3_MYOLU TNFSF10 TNFSF10 G1Q5X6_MYOLU G1Q5X6_MYOLU LOC102419640 LOC102419640 LOC102420929 LOC102420929 H1-6 H1-6 DFFB DFFB G1Q313_MYOLU G1Q313_MYOLU HMGB1 HMGB1 SEPTIN4 SEPTIN4 LOC102429902 LOC102429902 ACIN1 ACIN1 G1Q0J5_MYOLU G1Q0J5_MYOLU BCAP29 BCAP29 G1Q051_MYOLU G1Q051_MYOLU APIP APIP G1PYM9_MYOLU G1PYM9_MYOLU BID BID BMX BMX YWHAZ YWHAZ DIABLO DIABLO CLSPN CLSPN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (233 aa)
PLECPlectin. (3473 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (668 aa)
HMGB4High mobility group box 4. (186 aa)
VIMVimentin; Belongs to the intermediate filament family. (482 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (481 aa)
FASFas cell surface death receptor. (338 aa)
APCAPC regulator of WNT signaling pathway. (2851 aa)
NMT1Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (496 aa)
KPNB1Karyopherin subunit beta 1. (878 aa)
MAP2Microtubule-associated protein. (1842 aa)
BOKBCL2 family apoptosis regulator BOK. (162 aa)
BCL2L10Uncharacterized protein. (179 aa)
G1QER2_MYOLUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (360 aa)
TMEM198Transmembrane protein 198. (360 aa)
G1QD33_MYOLUUncharacterized protein. (188 aa)
ENSMLUP00000021529annotation not available (72 aa)
HMGB2High mobility group box 2. (207 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (665 aa)
LOC102428639Dynein light chain. (88 aa)
LOC102443111DUF4203 domain-containing protein. (355 aa)
ENSMLUP00000020832annotation not available (105 aa)
G1QAC1_MYOLU14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (244 aa)
LOC102423054H15 domain-containing protein. (221 aa)
GSNGelsolin. (782 aa)
DFFADNA fragmentation factor subunit alpha. (331 aa)
IGDCC3Immunoglobulin superfamily DCC subclass member 3. (819 aa)
IGDCC4Immunoglobulin superfamily DCC subclass member 4. (972 aa)
DAPK2Death associated protein kinase 2. (340 aa)
HP1BP3Heterochromatin protein 1 binding protein 3. (557 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
BNIP5BCL2 interacting protein 5. (618 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (543 aa)
CASP6Caspase 6; Belongs to the peptidase C14A family. (278 aa)
G1NUV7_MYOLUUncharacterized protein. (314 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (217 aa)
STK26Serine/threonine kinase 26. (419 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
SATB1DNA-binding protein SATB. (766 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
SEPTIN5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (394 aa)
DUS4LDihydrouridine synthase 4 like. (237 aa)
FNTAFarnesyltransferase, CAAX box, alpha. (329 aa)
CD14CD14 molecule. (365 aa)
GSDMBGasdermin B. (398 aa)
DSG1Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1052 aa)
DSG3Desmoglein 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (986 aa)
DSG2Desmoglein 2. (1119 aa)
APC2APC regulator of WNT signaling pathway 2. (2288 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (269 aa)
G1P1I5_MYOLUProtein kinase C. (615 aa)
BCAP31B cell receptor associated protein 31. (272 aa)
G1P2R3_MYOLUUncharacterized protein. (222 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1757 aa)
BCL2L2BH4_2 domain-containing protein. (219 aa)
MAPTMicrotubule-associated protein. (764 aa)
LOC102417162H15 domain-containing protein. (213 aa)
ADD1Adducin 1. (733 aa)
YWHAQTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (245 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (487 aa)
G1P5Y1_MYOLUMitogen-activated protein kinase. (321 aa)
DAPK3Death associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (843 aa)
FASLGTumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (280 aa)
SEPTIN1Septin 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (367 aa)
BADBCL2 associated agonist of cell death. (174 aa)
PMAIP1Uncharacterized protein. (54 aa)
STK25Serine/threonine kinase 25. (426 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (662 aa)
BCL2L1BCL2 like 1. (233 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2511 aa)
PPP3CCSerine/threonine-protein phosphatase. (500 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (521 aa)
BMFBcl2 modifying factor. (184 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1252 aa)
G1PBK4_MYOLUUncharacterized protein. (427 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (941 aa)
CTNNB1Catenin beta 1. (782 aa)
DSPDesmoplakin. (2865 aa)
G1PDJ5_MYOLUBclx_interact domain-containing protein. (70 aa)
SCINScinderin. (715 aa)
DCCUncharacterized protein. (1124 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (416 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (586 aa)
SFN14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (249 aa)
BAXBCL2 associated X, apoptosis regulator. (193 aa)
DYNLL1Dynein light chain. (89 aa)
LOC102439769Dynein light chain. (85 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (926 aa)
HMGB3Uncharacterized protein. (204 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1074 aa)
TRADDTNFRSF1A associated via death domain. (310 aa)
GSDMEGasdermin E. (496 aa)
G1PHJ2_MYOLUUncharacterized protein; Belongs to the MAGUK family. (1230 aa)
SH3GLB2SH3 domain containing GRB2 like, endophilin B2. (375 aa)
MAPK3Mitogen-activated protein kinase. (370 aa)
DBNLDrebrin like. (423 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (364 aa)
DAPK1Death associated protein kinase 1. (1108 aa)
STK24Serine/threonine kinase 24. (421 aa)
UNC5BUnc-5 netrin receptor B. (923 aa)
LMNB2Lamin B2; Belongs to the intermediate filament family. (607 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (764 aa)
OMA1OMA1 zinc metallopeptidase. (508 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1356 aa)
LMNTD1Lamin tail domain containing 1. (393 aa)
H1-0H1 histone family member 0. (194 aa)
LOC102421025Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
DYNLL2Dynein light chain. (89 aa)
G1Q8P3_MYOLUUncharacterized protein. (143 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (281 aa)
G1Q5X6_MYOLUUncharacterized protein. (145 aa)
LOC102419640Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC102420929Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa)
H1-6Histone cluster 1 H1 family member t. (210 aa)
DFFBDFF40 domain-containing protein. (189 aa)
G1Q313_MYOLUUncharacterized protein. (191 aa)
HMGB1Uncharacterized protein. (215 aa)
SEPTIN4Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (586 aa)
LOC102429902Uncharacterized protein. (162 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (703 aa)
G1Q0J5_MYOLUUncharacterized protein. (145 aa)
BCAP29B cell receptor associated protein 29. (237 aa)
G1Q051_MYOLUBH4_2 domain-containing protein. (206 aa)
APIPMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (257 aa)
G1PYM9_MYOLUH15 domain-containing protein. (318 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (191 aa)
BMXTyrosine-protein kinase. (650 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (247 aa)
DIABLOUncharacterized protein. (238 aa)
CLSPNClaspin. (1331 aa)
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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