STRINGSTRING
BIRC2 BIRC2 BIRC3 BIRC3 YWHAG YWHAG CASP8 CASP8 FAS FAS CHMP4B CHMP4B RIPK3 RIPK3 APC APC NMT1 NMT1 KPNB1 KPNB1 MAP2 MAP2 CHMP2A CHMP2A H1-0 H1-0 LMNTD1 LMNTD1 IRF2 IRF2 ROCK1 ROCK1 OMA1 OMA1 DNM1L DNM1L LMNB2 LMNB2 UNC5B UNC5B STK24 STK24 DAPK1 DAPK1 SH3GLB1 SH3GLB1 DBNL DBNL MAPK3 MAPK3 SH3GLB2 SH3GLB2 G1PHJ2_MYOLU G1PHJ2_MYOLU GSDME GSDME TRADD TRADD PTK2 PTK2 HMGB3 HMGB3 TJP3 TJP3 ELANE ELANE STUB1 STUB1 LOC102439769 LOC102439769 DYNLL1 DYNLL1 BAX BAX SFN SFN IL1B IL1B LMNB1 LMNB1 CASP9 CASP9 DCC DCC SCIN SCIN G1PDJ5_MYOLU G1PDJ5_MYOLU CHMP2B CHMP2B DSP DSP CTNNB1 CTNNB1 OPA1 OPA1 G1PBK4_MYOLU G1PBK4_MYOLU APAF1 APAF1 OGT OGT BMF BMF OCLN OCLN PPP3CC PPP3CC G1P9W7_MYOLU G1P9W7_MYOLU G1P9V1_MYOLU G1P9V1_MYOLU SPTAN1 SPTAN1 BCL2L1 BCL2L1 APPL2 APPL2 STK25 STK25 PMAIP1 PMAIP1 BAD BAD CHMP7 CHMP7 SEPTIN1 SEPTIN1 PDCD6IP PDCD6IP FASLG FASLG CDH1 CDH1 YWHAB YWHAB DAPK3 DAPK3 G1P5Y1_MYOLU G1P5Y1_MYOLU CFLAR CFLAR YWHAQ YWHAQ ADD1 ADD1 LOC102417162 LOC102417162 MAPT MAPT BCL2L2 BCL2L2 G1P2R3_MYOLU G1P2R3_MYOLU TJP1 TJP1 BCAP31 BCAP31 G1P1I5_MYOLU G1P1I5_MYOLU CASP7 CASP7 APC2 APC2 PRKN PRKN DSG2 DSG2 DSG3 DSG3 DSG1 DSG1 GSDMB GSDMB CD14 CD14 PELI1 PELI1 FNTA FNTA TTC6 TTC6 DUS4L DUS4L SEPTIN5 SEPTIN5 CASP3 CASP3 KXD1 KXD1 SATB1 SATB1 XIAP XIAP YWHAE YWHAE STK26 STK26 YWHAH YWHAH G1NUV7_MYOLU G1NUV7_MYOLU CASP6 CASP6 KPNA1 KPNA1 PRKCD PRKCD BNIP5 BNIP5 APPL1 APPL1 HP1BP3 HP1BP3 DAPK2 DAPK2 IGDCC4 IGDCC4 IGDCC3 IGDCC3 G1NTF8_MYOLU G1NTF8_MYOLU DFFA DFFA IL1A IL1A GSN GSN LOC102423054 LOC102423054 CHMP4C CHMP4C HMGB4 HMGB4 RIPK1 RIPK1 IRF1 IRF1 PLEC PLEC LOC102420450 LOC102420450 CLSPN CLSPN DIABLO DIABLO YWHAZ YWHAZ CHMP3 CHMP3 BMX BMX G1PYD9_MYOLU G1PYD9_MYOLU BID BID G1PYM9_MYOLU G1PYM9_MYOLU APIP APIP G1Q051_MYOLU G1Q051_MYOLU BCAP29 BCAP29 G1Q0J5_MYOLU G1Q0J5_MYOLU MLKL MLKL ACIN1 ACIN1 LOC102429902 LOC102429902 SEPTIN4 SEPTIN4 G1Q265_MYOLU G1Q265_MYOLU HMGB1 HMGB1 G1Q2S7_MYOLU G1Q2S7_MYOLU G1Q313_MYOLU G1Q313_MYOLU DFFB DFFB H1-6 H1-6 UBA52 UBA52 G1Q520_MYOLU G1Q520_MYOLU LOC102420929 LOC102420929 G1Q587_MYOLU G1Q587_MYOLU LOC102419640 LOC102419640 G1Q5X6_MYOLU G1Q5X6_MYOLU UBB UBB TNFSF10 TNFSF10 G1Q6T7_MYOLU G1Q6T7_MYOLU G1Q6X4_MYOLU G1Q6X4_MYOLU G1Q7W4_MYOLU G1Q7W4_MYOLU LOC102423287 LOC102423287 G1Q8P3_MYOLU G1Q8P3_MYOLU MDP1 MDP1 DYNLL2 DYNLL2 LOC102421025 LOC102421025 G1QAC1_MYOLU G1QAC1_MYOLU G1QAL8_MYOLU G1QAL8_MYOLU ENSMLUP00000020832 ENSMLUP00000020832 LOC102442670 LOC102442670 LOC102443111 LOC102443111 G1QBI4_MYOLU G1QBI4_MYOLU LOC102428639 LOC102428639 G1QC31_MYOLU G1QC31_MYOLU LMNA LMNA HMGB2 HMGB2 ENSMLUP00000021529 ENSMLUP00000021529 G1QD33_MYOLU G1QD33_MYOLU ENSMLUP00000021652 ENSMLUP00000021652 TMEM198 TMEM198 G1QDQ7_MYOLU G1QDQ7_MYOLU LOC102430695 LOC102430695 G1QER2_MYOLU G1QER2_MYOLU BCL2L10 BCL2L10 BOK BOK G1QGB2_MYOLU G1QGB2_MYOLU G1QGB8_MYOLU G1QGB8_MYOLU VIM VIM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BIRC2Baculoviral IAP repeat containing 2. (621 aa)
BIRC3Baculoviral IAP repeat containing 3. (603 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (481 aa)
FASFas cell surface death receptor. (338 aa)
CHMP4BCharged multivesicular body protein 4B. (228 aa)
RIPK3Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily. (499 aa)
APCAPC regulator of WNT signaling pathway. (2851 aa)
NMT1Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (496 aa)
KPNB1Karyopherin subunit beta 1. (878 aa)
MAP2Microtubule-associated protein. (1842 aa)
CHMP2ACharged multivesicular body protein 2A. (224 aa)
H1-0H1 histone family member 0. (194 aa)
LMNTD1Lamin tail domain containing 1. (393 aa)
IRF2Interferon regulatory factor. (349 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1356 aa)
OMA1OMA1 zinc metallopeptidase. (508 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (764 aa)
LMNB2Lamin B2; Belongs to the intermediate filament family. (607 aa)
UNC5BUnc-5 netrin receptor B. (923 aa)
STK24Serine/threonine kinase 24. (421 aa)
DAPK1Death associated protein kinase 1. (1108 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (364 aa)
DBNLDrebrin like. (423 aa)
MAPK3Mitogen-activated protein kinase. (370 aa)
SH3GLB2SH3 domain containing GRB2 like, endophilin B2. (375 aa)
G1PHJ2_MYOLUUncharacterized protein; Belongs to the MAGUK family. (1230 aa)
GSDMEGasdermin E. (496 aa)
TRADDTNFRSF1A associated via death domain. (310 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1074 aa)
HMGB3Uncharacterized protein. (204 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (926 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (241 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
LOC102439769Dynein light chain. (85 aa)
DYNLL1Dynein light chain. (89 aa)
BAXBCL2 associated X, apoptosis regulator. (193 aa)
SFN14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (249 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (586 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (416 aa)
DCCUncharacterized protein. (1124 aa)
SCINScinderin. (715 aa)
G1PDJ5_MYOLUBclx_interact domain-containing protein. (70 aa)
CHMP2BCharged multivesicular body protein 2B. (213 aa)
DSPDesmoplakin. (2865 aa)
CTNNB1Catenin beta 1. (782 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (941 aa)
G1PBK4_MYOLUUncharacterized protein. (427 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1252 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1036 aa)
BMFBcl2 modifying factor. (184 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (521 aa)
PPP3CCSerine/threonine-protein phosphatase. (500 aa)
G1P9W7_MYOLUUncharacterized protein; Belongs to the peptidase C14A family. (404 aa)
G1P9V1_MYOLUUncharacterized protein; Belongs to the peptidase C14A family. (376 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2511 aa)
BCL2L1BCL2 like 1. (233 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (662 aa)
STK25Serine/threonine kinase 25. (426 aa)
PMAIP1Uncharacterized protein. (54 aa)
BADBCL2 associated agonist of cell death. (174 aa)
CHMP7Charged multivesicular body protein 7. (453 aa)
SEPTIN1Septin 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (367 aa)
PDCD6IPBRO1 domain-containing protein. (908 aa)
FASLGTumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (280 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (843 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
DAPK3Death associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa)
G1P5Y1_MYOLUMitogen-activated protein kinase. (321 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (487 aa)
YWHAQTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (245 aa)
ADD1Adducin 1. (733 aa)
LOC102417162H15 domain-containing protein. (213 aa)
MAPTMicrotubule-associated protein. (764 aa)
BCL2L2BH4_2 domain-containing protein. (219 aa)
G1P2R3_MYOLUUncharacterized protein. (222 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1757 aa)
BCAP31B cell receptor associated protein 31. (272 aa)
G1P1I5_MYOLUProtein kinase C. (615 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (269 aa)
APC2APC regulator of WNT signaling pathway 2. (2288 aa)
PRKNParkin RBR E3 ubiquitin protein ligase. (365 aa)
DSG2Desmoglein 2. (1119 aa)
DSG3Desmoglein 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (986 aa)
DSG1Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1052 aa)
GSDMBGasdermin B. (398 aa)
CD14CD14 molecule. (365 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (419 aa)
FNTAFarnesyltransferase, CAAX box, alpha. (329 aa)
TTC6Tetratricopeptide repeat domain 6. (617 aa)
DUS4LDihydrouridine synthase 4 like. (237 aa)
SEPTIN5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (394 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
KXD1KxDL motif containing 1. (176 aa)
SATB1DNA-binding protein SATB. (766 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (233 aa)
STK26Serine/threonine kinase 26. (419 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (217 aa)
G1NUV7_MYOLUUncharacterized protein. (314 aa)
CASP6Caspase 6; Belongs to the peptidase C14A family. (278 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (543 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
BNIP5BCL2 interacting protein 5. (618 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
HP1BP3Heterochromatin protein 1 binding protein 3. (557 aa)
DAPK2Death associated protein kinase 2. (340 aa)
IGDCC4Immunoglobulin superfamily DCC subclass member 4. (972 aa)
IGDCC3Immunoglobulin superfamily DCC subclass member 3. (819 aa)
G1NTF8_MYOLUUncharacterized protein; Belongs to the peptidase C14A family. (413 aa)
DFFADNA fragmentation factor subunit alpha. (331 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (269 aa)
GSNGelsolin. (782 aa)
LOC102423054H15 domain-containing protein. (221 aa)
CHMP4CCharged multivesicular body protein 4C. (231 aa)
HMGB4High mobility group box 4. (186 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (668 aa)
IRF1Interferon regulatory factor. (328 aa)
PLECPlectin. (3473 aa)
LOC102420450Ubiquitin-like domain-containing protein. (156 aa)
CLSPNClaspin. (1331 aa)
DIABLOUncharacterized protein. (238 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (247 aa)
CHMP3Uncharacterized protein. (210 aa)
BMXTyrosine-protein kinase. (650 aa)
G1PYD9_MYOLUUbiquitin-like domain-containing protein. (123 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (191 aa)
G1PYM9_MYOLUH15 domain-containing protein. (318 aa)
APIPMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (257 aa)
G1Q051_MYOLUBH4_2 domain-containing protein. (206 aa)
BCAP29B cell receptor associated protein 29. (237 aa)
G1Q0J5_MYOLUUncharacterized protein. (145 aa)
MLKLMixed lineage kinase domain like pseudokinase. (476 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (703 aa)
LOC102429902Uncharacterized protein. (162 aa)
SEPTIN4Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (586 aa)
G1Q265_MYOLUNACHT domain-containing protein. (1443 aa)
HMGB1Uncharacterized protein. (215 aa)
G1Q2S7_MYOLUUbiquitin-like domain-containing protein. (156 aa)
G1Q313_MYOLUUncharacterized protein. (191 aa)
DFFBDFF40 domain-containing protein. (189 aa)
H1-6Histone cluster 1 H1 family member t. (210 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (127 aa)
G1Q520_MYOLUUncharacterized protein; Belongs to the peptidase C14A family. (369 aa)
LOC102420929Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa)
G1Q587_MYOLUUBIQUITIN_CONJUGAT_2 domain-containing protein. (152 aa)
LOC102419640Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
G1Q5X6_MYOLUUncharacterized protein. (145 aa)
UBBUncharacterized protein. (114 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (281 aa)
G1Q6T7_MYOLUUncharacterized protein; Belongs to the peptidase C14A family. (285 aa)
G1Q6X4_MYOLUUncharacterized protein. (84 aa)
G1Q7W4_MYOLUUbiquitin-like domain-containing protein. (128 aa)
LOC102423287Uncharacterized protein; Belongs to the peptidase C14A family. (259 aa)
G1Q8P3_MYOLUUncharacterized protein. (143 aa)
MDP1Uncharacterized protein. (163 aa)
DYNLL2Dynein light chain. (89 aa)
LOC102421025Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
G1QAC1_MYOLU14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (244 aa)
G1QAL8_MYOLUUncharacterized protein. (201 aa)
ENSMLUP00000020832annotation not available (105 aa)
LOC102442670Uncharacterized protein. (305 aa)
LOC102443111DUF4203 domain-containing protein. (355 aa)
G1QBI4_MYOLUUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
LOC102428639Dynein light chain. (88 aa)
G1QC31_MYOLUUbiquitin-like domain-containing protein. (155 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (665 aa)
HMGB2High mobility group box 2. (207 aa)
ENSMLUP00000021529annotation not available (72 aa)
G1QD33_MYOLUUncharacterized protein. (188 aa)
ENSMLUP00000021652annotation not available (162 aa)
TMEM198Transmembrane protein 198. (360 aa)
G1QDQ7_MYOLUUbiquitin-like domain-containing protein. (155 aa)
LOC102430695Ubiquitin-like domain-containing protein. (128 aa)
G1QER2_MYOLUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (360 aa)
BCL2L10Uncharacterized protein. (179 aa)
BOKBCL2 family apoptosis regulator BOK. (162 aa)
G1QGB2_MYOLUUbiquitin-like domain-containing protein. (117 aa)
G1QGB8_MYOLUUncharacterized protein; Belongs to the peptidase C14A family. (281 aa)
VIMVimentin; Belongs to the intermediate filament family. (482 aa)
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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