STRINGSTRING
G1Q7H9_MYOLU G1Q7H9_MYOLU UBB UBB UBA52 UBA52 MDM4 MDM4 SSRP1 SSRP1 TPX2 TPX2 RPA3 RPA3 HIPK1 HIPK1 AURKC AURKC HIPK4 HIPK4 AURKA AURKA SUPT16H SUPT16H NOC2L NOC2L TAF13 TAF13 PIN1 PIN1 ANKRD12 ANKRD12 G1PC16_MYOLU G1PC16_MYOLU KAT5 KAT5 NBN NBN G1PCP6_MYOLU G1PCP6_MYOLU G1PD06_MYOLU G1PD06_MYOLU SLF1 SLF1 CSNK2B CSNK2B TAF2 TAF2 MDM2 MDM2 CSNK2A1 CSNK2A1 TAF4 TAF4 L7N1K2_MYOLU L7N1K2_MYOLU PRKAG1 PRKAG1 G1PHV0_MYOLU G1PHV0_MYOLU RECQL4 RECQL4 NUAK2 NUAK2 EXD2 EXD2 TP53RK TP53RK TAF12 TAF12 TP53INP1 TP53INP1 DYRK2 DYRK2 RFC3 RFC3 BARD1 BARD1 PRKAA1 PRKAA1 PRKAA2 PRKAA2 G1PQ28_MYOLU G1PQ28_MYOLU RBBP8 RBBP8 TAF9B TAF9B TBP TBP BLM BLM CDK5 CDK5 STK11 STK11 HIPK3 HIPK3 DNA2 DNA2 RAD1 RAD1 PRKAB1 PRKAB1 G1Q221_MYOLU G1Q221_MYOLU RAD9B RAD9B TBPL2 TBPL2 MAPKAPK5 MAPKAPK5 RFC4 RFC4 ANKRD11 ANKRD11 RAD50 RAD50 CHEK2 CHEK2 G1PVA9_MYOLU G1PVA9_MYOLU ATR ATR LOC102420450 LOC102420450 TAF7L TAF7L HIPK2 HIPK2 ATRIP ATRIP G1PYD9_MYOLU G1PYD9_MYOLU CDK5R1 CDK5R1 G1PZ51_MYOLU G1PZ51_MYOLU G1Q060_MYOLU G1Q060_MYOLU TAF10 TAF10 LY6G5B LY6G5B G1Q3D2_MYOLU G1Q3D2_MYOLU RMI1 RMI1 G1Q2X3_MYOLU G1Q2X3_MYOLU G1Q2W7_MYOLU G1Q2W7_MYOLU G1Q2S7_MYOLU G1Q2S7_MYOLU LOC102429896 LOC102429896 G1QGB2_MYOLU G1QGB2_MYOLU G1QG66_MYOLU G1QG66_MYOLU LOC102443195 LOC102443195 TAF5 TAF5 TP53INP2 TP53INP2 NUAK1 NUAK1 LOC102437265 LOC102437265 TP53 TP53 RPA1 RPA1 WRN WRN CHEK1 CHEK1 TOPBP1 TOPBP1 CCNA2 CCNA2 RAD9A RAD9A CDK2 CDK2 RFC2 RFC2 PRKAG2 PRKAG2 BRCA1 BRCA1 PRKAG3 PRKAG3 G1P107_MYOLU G1P107_MYOLU AURKB AURKB TAF15 TAF15 DYRK4 DYRK4 TAF3 TAF3 KXD1 KXD1 TBPL1 TBPL1 MRE11 MRE11 L7N119_MYOLU L7N119_MYOLU TAF7 TAF7 RAD17 RAD17 TAF11 TAF11 DYRK3 DYRK3 CDK3 CDK3 MEIOB MEIOB HUS1 HUS1 CCNA1 CCNA1 CSNK2A2 CSNK2A2 TOP3A TOP3A TDRD3 TDRD3 LOC102430695 LOC102430695 G1QDQ7_MYOLU G1QDQ7_MYOLU CDK5R2 CDK5R2 ENSMLUP00000021652 ENSMLUP00000021652 RHNO1 RHNO1 G1QC31_MYOLU G1QC31_MYOLU LOC102437556 LOC102437556 LOC102442670 LOC102442670 G1Q9J5_MYOLU G1Q9J5_MYOLU G1Q980_MYOLU G1Q980_MYOLU G1Q8Z6_MYOLU G1Q8Z6_MYOLU G1Q8T5_MYOLU G1Q8T5_MYOLU G1Q7W4_MYOLU G1Q7W4_MYOLU
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G1Q7H9_MYOLUTAF domain-containing protein. (439 aa)
UBBUncharacterized protein. (114 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (127 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (492 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (710 aa)
TPX2TPX2 microtubule nucleation factor. (737 aa)
RPA3Replication protein A3. (118 aa)
HIPK1Homeodomain interacting protein kinase 1. (1213 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (225 aa)
HIPK4Homeodomain interacting protein kinase 4. (611 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (408 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
NOC2LNOC2 like nucleolar associated transcriptional repressor. (701 aa)
TAF13Uncharacterized protein. (124 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
ANKRD12Ankyrin repeat domain 12. (2055 aa)
G1PC16_MYOLUTranscription initiation factor TFIID subunit. (1865 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (756 aa)
G1PCP6_MYOLUUncharacterized protein. (218 aa)
G1PD06_MYOLUTranscription initiation factor TFIID subunit. (1870 aa)
SLF1SMC5-SMC6 complex localization factor 1. (1057 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
TAF2TATA-box binding protein associated factor 2. (1198 aa)
MDM2MDM2 proto-oncogene. (499 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
TAF4TATA-box binding protein associated factor 4. (637 aa)
L7N1K2_MYOLUUncharacterized protein; Belongs to the cyclin family. (297 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (329 aa)
G1PHV0_MYOLUFAT domain-containing protein. (2192 aa)
RECQL4RecQ like helicase 4. (1228 aa)
NUAK2NUAK family kinase 2. (657 aa)
EXD2Exonuclease 3'-5' domain containing 2. (510 aa)
TP53RKTP53 regulating kinase. (258 aa)
TAF12TATA-box binding protein associated factor 12. (161 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (238 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (596 aa)
RFC3Replication factor C subunit 3. (356 aa)
BARD1BRCA1 associated RING domain 1. (729 aa)
PRKAA1Non-specific serine/threonine protein kinase. (517 aa)
PRKAA2Non-specific serine/threonine protein kinase. (528 aa)
G1PQ28_MYOLUAMPKBI domain-containing protein. (221 aa)
RBBP8RB binding protein 8, endonuclease. (895 aa)
TAF9BTATA-box binding protein associated factor 9b. (261 aa)
TBPTATA-box binding protein. (318 aa)
BLMBLM RecQ like helicase. (1410 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (294 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (441 aa)
HIPK3Homeodomain interacting protein kinase 3. (1214 aa)
DNA2Uncharacterized protein. (1035 aa)
RAD1RAD1 checkpoint DNA exonuclease. (281 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
G1Q221_MYOLUTAF domain-containing protein. (426 aa)
RAD9BRAD9 checkpoint clamp component B. (328 aa)
TBPL2TATA-box binding protein like 2. (356 aa)
MAPKAPK5Protein kinase domain-containing protein. (463 aa)
RFC4Replication factor C subunit 4. (366 aa)
ANKRD11Ankyrin repeat domain 11. (2657 aa)
RAD50Zinc-hook domain-containing protein. (1316 aa)
CHEK2Checkpoint kinase 2. (543 aa)
G1PVA9_MYOLUTAFH domain-containing protein. (747 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2566 aa)
LOC102420450Ubiquitin-like domain-containing protein. (156 aa)
TAF7LTATA-box binding protein associated factor 7 like. (472 aa)
HIPK2Homeodomain interacting protein kinase 2. (1190 aa)
ATRIPATR interacting protein. (695 aa)
G1PYD9_MYOLUUbiquitin-like domain-containing protein. (123 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
G1PZ51_MYOLUCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (388 aa)
G1Q060_MYOLUUncharacterized protein. (121 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (144 aa)
LY6G5BLymphocyte antigen 6 family member G5B. (195 aa)
G1Q3D2_MYOLUHomeobox domain-containing protein. (309 aa)
RMI1RecQ mediated genome instability 1. (616 aa)
G1Q2X3_MYOLUAAA domain-containing protein. (332 aa)
G1Q2W7_MYOLUTAF6_C domain-containing protein. (482 aa)
G1Q2S7_MYOLUUbiquitin-like domain-containing protein. (156 aa)
LOC102429896XPGI domain-containing protein. (714 aa)
G1QGB2_MYOLUUbiquitin-like domain-containing protein. (117 aa)
G1QG66_MYOLUUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1083 aa)
LOC102443195Uncharacterized protein. (124 aa)
TAF5TATA-box binding protein associated factor 5. (615 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (221 aa)
NUAK1NUAK family kinase 1. (666 aa)
LOC102437265Dna2 domain-containing protein. (356 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (621 aa)
WRNWRN RecQ like helicase. (1386 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (478 aa)
TOPBP1DNA topoisomerase II binding protein 1. (1523 aa)
CCNA2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (427 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (390 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
RFC2AAA domain-containing protein. (352 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (320 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1852 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (496 aa)
G1P107_MYOLUUncharacterized protein. (246 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (339 aa)
TAF15TATA-box binding protein associated factor 15. (518 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (565 aa)
TAF3TATA-box binding protein associated factor 3. (796 aa)
KXD1KxDL motif containing 1. (176 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (714 aa)
L7N119_MYOLUUncharacterized protein. (790 aa)
TAF7TATA-box binding protein associated factor 7. (360 aa)
RAD17RAD17 checkpoint clamp loader component. (683 aa)
TAF11TATA-box binding protein associated factor 11. (208 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (586 aa)
CDK3Cyclin dependent kinase 3. (241 aa)
MEIOBMeiosis specific with OB-fold. (473 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (265 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (431 aa)
CSNK2A2Casein kinase 2 alpha 2. (281 aa)
TOP3ADNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1004 aa)
TDRD3Tudor domain containing 3. (685 aa)
LOC102430695Ubiquitin-like domain-containing protein. (128 aa)
G1QDQ7_MYOLUUbiquitin-like domain-containing protein. (155 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (369 aa)
ENSMLUP00000021652annotation not available (162 aa)
RHNO1RAD9-HUS1-RAD1 interacting nuclear orphan 1. (243 aa)
G1QC31_MYOLUUbiquitin-like domain-containing protein. (155 aa)
LOC102437556TAFH domain-containing protein. (494 aa)
LOC102442670Uncharacterized protein. (305 aa)
G1Q9J5_MYOLUAMPK1_CBM domain-containing protein. (183 aa)
G1Q980_MYOLUCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (283 aa)
G1Q8Z6_MYOLUTAFII28 domain-containing protein. (216 aa)
G1Q8T5_MYOLUUncharacterized protein. (80 aa)
G1Q7W4_MYOLUUbiquitin-like domain-containing protein. (128 aa)
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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