STRINGSTRING
G1NXA5_MYOLU G1NXA5_MYOLU ARRB1 ARRB1 G1QFK7_MYOLU G1QFK7_MYOLU G1QGB2_MYOLU G1QGB2_MYOLU LRP2 LRP2 AGFG2 AGFG2 IL7R IL7R SYT11 SYT11 IGF2R IGF2R UBQLN4 UBQLN4 NETO1 NETO1 STON2 STON2 M6PR M6PR SH3GL1 SH3GL1 COPS5 COPS5 G1PIZ0_MYOLU G1PIZ0_MYOLU UBL7 UBL7 CFTR CFTR EPN2 EPN2 VAMP7 VAMP7 SH3KBP1 SH3KBP1 EPN1 EPN1 SLC2A8 SLC2A8 AP2M1 AP2M1 COPS2 COPS2 COPS7A COPS7A CD3D CD3D CD3G CD3G COPS6 COPS6 AVPR2 AVPR2 SYT2 SYT2 GRB2 GRB2 EREG EREG AREG AREG EGF EGF AP2A2 AP2A2 COPS3 COPS3 VAMP3 VAMP3 CLHC1 CLHC1 TGFA TGFA SYT4 SYT4 GPS1 GPS1 VAMP4 VAMP4 LOC102420450 LOC102420450 AP2A1 AP2A1 FCHO2 FCHO2 CHRM2 CHRM2 STAM STAM LOC102442363 LOC102442363 G1PYD9_MYOLU G1PYD9_MYOLU ITSN1 ITSN1 LOC102436839 LOC102436839 SCARB2 SCARB2 HGS HGS G1Q2S7_MYOLU G1Q2S7_MYOLU LOC102436219 LOC102436219 G1Q2Z6_MYOLU G1Q2Z6_MYOLU G1Q3G5_MYOLU G1Q3G5_MYOLU VAMP5 VAMP5 SLC18A3 SLC18A3 UBA52 UBA52 LOC102431899 LOC102431899 G1Q5C4_MYOLU G1Q5C4_MYOLU G1Q5M0_MYOLU G1Q5M0_MYOLU G1Q5Y7_MYOLU G1Q5Y7_MYOLU ZFYVE19 ZFYVE19 UBB UBB AGFG1 AGFG1 G1Q7W4_MYOLU G1Q7W4_MYOLU ENSMLUP00000019887 ENSMLUP00000019887 G1Q8D4_MYOLU G1Q8D4_MYOLU LOC102423130 LOC102423130 G1Q9S4_MYOLU G1Q9S4_MYOLU CD4 CD4 LOC102442670 LOC102442670 FZD4 FZD4 G1QC31_MYOLU G1QC31_MYOLU EPGN EPGN ENSMLUP00000021598 ENSMLUP00000021598 ENSMLUP00000021620 ENSMLUP00000021620 ENSMLUP00000021652 ENSMLUP00000021652 G1QDQ7_MYOLU G1QDQ7_MYOLU LOC102430695 LOC102430695 UBQLN2 UBQLN2 G1QF72_MYOLU G1QF72_MYOLU G1QFI9_MYOLU G1QFI9_MYOLU AAK1 AAK1 TACR1 TACR1 BMP2K BMP2K G1PBY2_MYOLU G1PBY2_MYOLU LOC102419138 LOC102419138 REPS2 REPS2 APOB APOB PPP1R42 PPP1R42 NECAP1 NECAP1 TOR1A TOR1A CLTA CLTA COPS8 COPS8 FCHO1 FCHO1 SNAP91 SNAP91 CBL CBL ADRB2 ADRB2 PICALM PICALM LOC102425940 LOC102425940 SYT1 SYT1 G1P5B5_MYOLU G1P5B5_MYOLU EPN3 EPN3 DAB2 DAB2 VAMP8 VAMP8 G1P4I2_MYOLU G1P4I2_MYOLU GRK2 GRK2 LDLRAP1 LDLRAP1 CLPB CLPB LDLR LDLR EPS15 EPS15 KIAA0319L KIAA0319L SYT9 SYT9 GPR21 GPR21 G1P0W6_MYOLU G1P0W6_MYOLU CLTC CLTC REPS1 REPS1 STAM2 STAM2 NETO2 NETO2 HBEGF HBEGF COPS4 COPS4 AP2B1 AP2B1 GPR52 GPR52 L7N137_MYOLU L7N137_MYOLU LMBRD2 LMBRD2 COPS7B COPS7B DVL2 DVL2 ARRB2 ARRB2 ITSN2 ITSN2 MCTP2 MCTP2 KXD1 KXD1 UBQLN1 UBQLN1 AGTR1 AGTR1 SH3GL2 SH3GL2 EPS15L1 EPS15L1 ENTHD1 ENTHD1 SGIP1 SGIP1 ZFYVE1 ZFYVE1 TFRC TFRC LOC102433960 LOC102433960
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G1NXA5_MYOLUUBA domain-containing protein. (552 aa)
ARRB1Arrestin beta 1. (414 aa)
G1QFK7_MYOLUUbiquitin-like domain-containing protein. (330 aa)
G1QGB2_MYOLUUbiquitin-like domain-containing protein. (117 aa)
LRP2LDL receptor related protein 2. (4655 aa)
AGFG2ArfGAP with FG repeats 2. (492 aa)
IL7RInterleukin 7 receptor. (457 aa)
SYT11Synaptotagmin 11. (432 aa)
IGF2RInsulin like growth factor 2 receptor. (2310 aa)
UBQLN4Uncharacterized protein. (564 aa)
NETO1Neuropilin and tolloid like 1. (533 aa)
STON2Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (899 aa)
M6PRMannose-6-phosphate receptor, cation dependent. (279 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (353 aa)
COPS5COP9 signalosome subunit 5. (334 aa)
G1PIZ0_MYOLUStonin-1; May be involved in the endocytic machinery. (1182 aa)
UBL7Ubiquitin like 7. (380 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1484 aa)
EPN2Epsin 2. (662 aa)
VAMP7Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (616 aa)
EPN1Epsin 1. (579 aa)
SLC2A8Solute carrier family 2 member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (481 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (441 aa)
COPS2COP9 signalosome subunit 2. (452 aa)
COPS7ACOP9 signalosome subunit 7A. (275 aa)
CD3DCD3d molecule. (171 aa)
CD3GCD3g molecule. (180 aa)
COPS6COP9 signalosome subunit 6. (328 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (367 aa)
SYT2Synaptotagmin 2. (268 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
EREGEpiregulin. (147 aa)
AREGAmphiregulin. (248 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1178 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (951 aa)
COPS3PCI domain-containing protein. (405 aa)
VAMP3Vesicle associated membrane protein 3. (103 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (586 aa)
TGFATransforming growth factor alpha. (128 aa)
SYT4Synaptotagmin 4. (427 aa)
GPS1G protein pathway suppressor 1. (479 aa)
VAMP4Vesicle associated membrane protein 4. (100 aa)
LOC102420450Ubiquitin-like domain-containing protein. (156 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (984 aa)
FCHO2FCH domain only 2. (814 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
STAMSignal transducing adaptor molecule. (523 aa)
LOC102442363Clat_adaptor_s domain-containing protein. (92 aa)
G1PYD9_MYOLUUbiquitin-like domain-containing protein. (123 aa)
ITSN1Intersectin 1. (1650 aa)
LOC102436839Torsin. (335 aa)
SCARB2Scavenger receptor class B member 2; Belongs to the CD36 family. (483 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (473 aa)
G1Q2S7_MYOLUUbiquitin-like domain-containing protein. (156 aa)
LOC102436219Torsin. (324 aa)
G1Q2Z6_MYOLUUncharacterized protein. (364 aa)
G1Q3G5_MYOLUG protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (618 aa)
VAMP5Vesicle associated membrane protein 5. (116 aa)
SLC18A3Solute carrier family 18 member A3. (496 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (127 aa)
LOC102431899Arrestin_C domain-containing protein. (91 aa)
G1Q5C4_MYOLUAP complex subunit beta. (648 aa)
G1Q5M0_MYOLUDUF1681 domain-containing protein. (248 aa)
G1Q5Y7_MYOLUC2 domain-containing protein. (185 aa)
ZFYVE19Zinc finger FYVE-type containing 19. (471 aa)
UBBUncharacterized protein. (114 aa)
AGFG1ArfGAP with FG repeats 1. (516 aa)
G1Q7W4_MYOLUUbiquitin-like domain-containing protein. (128 aa)
ENSMLUP00000019887annotation not available (153 aa)
G1Q8D4_MYOLUEGF-like domain-containing protein. (669 aa)
LOC102423130Ubiquitin-like domain-containing protein. (41 aa)
G1Q9S4_MYOLUUncharacterized protein. (306 aa)
CD4CD4 molecule. (447 aa)
LOC102442670Uncharacterized protein. (305 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (536 aa)
G1QC31_MYOLUUbiquitin-like domain-containing protein. (155 aa)
EPGNEpithelial mitogen. (153 aa)
ENSMLUP00000021598annotation not available (92 aa)
ENSMLUP00000021620annotation not available (48 aa)
ENSMLUP00000021652annotation not available (162 aa)
G1QDQ7_MYOLUUbiquitin-like domain-containing protein. (155 aa)
LOC102430695Ubiquitin-like domain-containing protein. (128 aa)
UBQLN2Ubiquilin 2. (625 aa)
G1QF72_MYOLUEGF-like domain-containing protein. (88 aa)
G1QFI9_MYOLUUncharacterized protein; Belongs to the transferrin family. (713 aa)
AAK1AP2 associated kinase 1. (916 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
BMP2KBMP2 inducible kinase. (1105 aa)
G1PBY2_MYOLUPCI domain-containing protein. (385 aa)
LOC102419138G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (635 aa)
REPS2RALBP1 associated Eps domain containing 2. (570 aa)
APOBApolipoprotein B. (4557 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (361 aa)
NECAP1NECAP endocytosis associated 1. (279 aa)
TOR1ATorsin family 1 member A. (370 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (246 aa)
COPS8COP9 signalosome subunit 8. (211 aa)
FCHO1FCH domain only 1. (884 aa)
SNAP91Synaptosome associated protein 91. (879 aa)
CBLCbl proto-oncogene. (842 aa)
ADRB2Adrenoceptor beta 2. (416 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (678 aa)
LOC102425940BAR domain-containing protein. (288 aa)
SYT1Synaptotagmin 1. (369 aa)
G1P5B5_MYOLUUncharacterized protein. (635 aa)
EPN3Epsin 3. (575 aa)
DAB2DAB adaptor protein 2. (768 aa)
VAMP8Vesicle associated membrane protein 8. (99 aa)
G1P4I2_MYOLUUncharacterized protein. (998 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (652 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (280 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (707 aa)
LDLRLow density lipoprotein receptor. (856 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (902 aa)
KIAA0319LKIAA0319 like. (1025 aa)
SYT9Synaptotagmin 9. (462 aa)
GPR21G protein-coupled receptor 21; Belongs to the G-protein coupled receptor 1 family. (349 aa)
G1P0W6_MYOLUC2 domain-containing protein. (357 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1661 aa)
REPS1RALBP1 associated Eps domain containing 1. (751 aa)
STAM2Signal transducing adaptor molecule 2. (533 aa)
NETO2Neuropilin and tolloid like 2. (524 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
COPS4COP9 signalosome subunit 4. (406 aa)
AP2B1AP complex subunit beta. (951 aa)
GPR52G protein-coupled receptor 52; Belongs to the G-protein coupled receptor 1 family. (361 aa)
L7N137_MYOLUEGF-like domain-containing protein. (152 aa)
LMBRD2LMBR1 domain containing 2. (717 aa)
COPS7BCOP9 signalosome subunit 7B. (264 aa)
DVL2Dishevelled segment polarity protein 2. (671 aa)
ARRB2Arrestin_C domain-containing protein. (306 aa)
ITSN2Intersectin 2. (1696 aa)
MCTP2Multiple C2 and transmembrane domain containing 2. (879 aa)
KXD1KxDL motif containing 1. (176 aa)
UBQLN1Ubiquilin 1. (588 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (369 aa)
EPS15L1Epidermal growth factor receptor pathway substrate 15 like 1. (909 aa)
ENTHD1ENTH domain containing 1. (617 aa)
SGIP1SH3 domain GRB2 like endophilin interacting protein 1. (859 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (791 aa)
TFRCTransferrin receptor. (765 aa)
LOC102433960DUF1681 domain-containing protein. (236 aa)
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
Server load: low (12%) [HD]